A5081126599- Molecular Sensors and Ion Detection
- Sulfur Compounds in Biology
- Photochemistry and Electron Transfer Studies
- Luminescence and Fluorescent Materials
- Organoselenium and organotellurium chemistry
- Electrocatalysts for Energy Conversion
- Advanced Nanomaterials in Catalysis
- Advanced Photocatalysis Techniques
- Photoreceptor and optogenetics research
- Nitric Oxide and Endothelin Effects
- Spectroscopy and Quantum Chemical Studies
- Analytical Chemistry and Sensors
- Catalytic Processes in Materials Science
- Porphyrin and Phthalocyanine Chemistry
- Redox biology and oxidative stress
- Advanced Memory and Neural Computing
- Photochromic and Fluorescence Chemistry
- Selenium in Biological Systems
- Fuel Cells and Related Materials
- Eicosanoids and Hypertension Pharmacology
- Animal Virus Infections Studies
- Lanthanide and Transition Metal Complexes
- Perovskite Materials and Applications
- Nanoplatforms for cancer theranostics
- Copper-based nanomaterials and applications
Dalian University of Technology
2014-2025
Shandong University
2020-2023
Dalian Institute of Chemical Physics
2012-2017
Chinese Academy of Sciences
2013-2017
Dalian University
2014-2017
University of Chinese Academy of Sciences
2013
We have developed a new reversible fluorescence probe MPhSe–BOD for the redox cycle process between hypochlorous acid and hydrogen sulfide in solution living cells. Confocal microscopy imaging using RAW264.7 cell lines shows that has good membrane permeability, can monitor intracellular HClO/H2S cycles continuously.
Based on a novel strategy for modulating the fluorescence of selenide and selenoxide, we have designed developed reversible fluorescent probe hypochloric acid. And synthesis, characterization, properties, as well biological applications in living cells animals, all been described.
Modulating electronic structures of single-atom metal cocatalysts is vital for highly active photoreduction CO2, and it's especially challenging to develop a facile method modify the dispersion atomical photocatalytic sites. We herein report an ion-loading pyrolysis route in-situ anchor Pd single atoms as well twinned nanoparticles on ultra-thin graphitic carbon nitride nanosheets (PdTP/PdSA-CN) high-efficiency CO2. The anchored donate electrons adjacent Pd–N4 sites through networks,...
A diselenide containing fluorescent probe based on a fluorescein scaffold for thiols was developed. The exhibited rapid response, high selectivity and reversibility. Confocal fluorescence microscopy used to visualize the redox changes mediated by reactive oxygen species in living HeLa cells.
A series of ratiometric probes based on heptamethine cyanine dyes for detecting hypochlorous acid have been developed. Here we present the synthesis, characterization and fluorescence properties these probes. And it turns out that are highly sensitive selective toward acid. More importantly, application in living cells imaging has achieved successfully.
It is well-known that the fluorescence of a chromophore can be efficiently quenched by free rotor effect, sometimes called intramolecular rotation (IMR), i.e. large-amplitude torsional motion. Using this aggregation induced enhanced emission (AIE) and fluorescent molecular probes for viscosity measurements have been devised. However, effect on triplet excited states was rarely studied. Herein, with rotors Bodipy diiodoBodipy, using steady state time-resolved transient absorption/emission...
This study examines the roles of Cyclin B1 (CCNB1), Polo-Like Kinase 1 (PLK1), and Heparanase (HPSE) in breast cancer progression using a multi-omics approach. These genes are known for their involvement various cancer-related processes, but precise contributions to remain unclear. We employed an integrative analysis combining transcriptomics, proteomics, DNA methylation profiling, immune infiltration analysis, single-cell RNA sequencing investigate expression patterns, regulatory...
In this article, the sensing mechanism of a fluorescence probe for hypochloric acid, NI-Se, has been investigated using experimental and theoretical methods. Based on results steady-state time-resolved emission spectra NI-Se its oxidized form NI-SeO, we suggested that there was twist internal charge transfer (TICT) state with faint in NI-Se. Subsequently, ground excited minimum geometries NI-SeO were optimized DFT/TD-DFT The demonstrated twisting process induced by nonbonding interaction...
The biological roles of reactive oxygen species (ROS) depend highly on their dynamics. However, it has been challenging for measuring the dynamics ROS in cells. In this study, we address a core challenge developing fluorescence probes monitoring by designing redox couple that can respond rapidly to both oxidation and reduction events. We show such molecules be designed taking advantage steric effects electron-donating groups at ortho position relative selenium center. demonstrate design new...
The twisted intramolecular charge transfer has been proposed for a number of years and widely accepted to explain the excited-state dynamics organic molecules. Recently, new state termed as "twisted rehybridized transfer" an aniline–triazine electron donor–acceptor dyad with alkyne spacer based on ultrafast time-resolved spectroscopy. However, change geometries along decay pathway remains unknown. In this study, by optimization geometry potential energy surface scan twisting angle, we...
Rhodamine-bromonaphthaleneimide (RB-NI) and rhodamine-bromonaphthalenediimide (RB-NDI) dyads were prepared for switching of the triplet excited states. Bromo-NI or bromo-NDI parts in are spin converters, i.e., state producing modules, whereas RB unit is acid-activatable electron donor/energy acceptor. NI NDI absorb at 359 541 nm, T1 energy levels 2.25 1.64 eV, respectively. undertakes reversible spirolactam (RB-c) ↔ opened amide (RB-o) transformation. RB-c shows no visible light absorption,...
Acid-switching of the triplet excited state in rhodamine-C60 dyads was achieved. The rhodamine moiety acts as an acid-activated visible light-harvesting antenna and C60 singlet energy acceptor spin converter, production enhanced presence acid.
Objective In past decades, the role of high-risk HPV (HR-HPV) infection in cancer pathogenesis has been extensively studied. The viral E7 protein expressed pre-malignant cells identified as an ideal target for immunological intervention. However, cultivation vitro remains a significant challenge, well lack methods expressing and generating replication-competent recombinant particles, which posed major obstacle to further exploration function carcinogenic mechanisms oncoprotein. Therefore, it...