A5091298025- Sepsis Diagnosis and Treatment
- Heparin-Induced Thrombocytopenia and Thrombosis
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Platelet Disorders and Treatments
- Blood transfusion and management
- Blood Coagulation and Thrombosis Mechanisms
- Hemodynamic Monitoring and Therapy
- Tracheal and airway disorders
- Renal function and acid-base balance
- Neonatal and Maternal Infections
- Cardiac Arrest and Resuscitation
- Venous Thromboembolism Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Voice and Speech Disorders
- COVID-19 and healthcare impacts
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Acute Kidney Injury Research
- Acute Myocardial Infarction Research
- Airway Management and Intubation Techniques
- Health, Medicine and Society
- Autoimmune Bullous Skin Diseases
- Chronic Kidney Disease and Diabetes
Helsinki University Hospital
2004-2024
University of Helsinki
2020-2024
Pain and Rehabilitation Medicine
2020
GTx (United States)
2009
Jorvi Hospital
2009
Severe sepsis induces coagulopathy, which may lead to disseminated intravascular coagulation (DIC). Thromboelastometry is a point-of-care whole blood monitor, has been validated in human endotoxemia model. We assessed thromboelastometry severe and overt DIC investigated its applicability differentiating sepsis-related disturbances. (EXTEM FIBTEM tests) traditional assays were analyzed 28 patients with sepsis, 12 of who fulfilled the criteria on admission. Ten healthy persons served as...
Background Matrix metalloproteinase‐8 ( MMP ‐8) and tissue inhibitor of metalloproteinases‐1 TIMP ‐1) have recently been suggested to be involved in coagulation process. Our objectives were observe systemic ‐8 ‐1 levels patients with severe sepsis or without disseminated intravascular DIC ) study their relationship markers over time. Methods prospective pilot included 22 sepsis, nine (41%) whom had overt . We analysed serum concentrations by time‐resolved immunofluorometric enzyme‐linked...
Platelet transfusions are frequently used in the intensive care unit (ICU), but current practices including product types, volumes, doses and effects unknown.
Standard subcutaneous low-molecular-weight heparin (LMWH) thromboprophylaxis yields low anti-factor Xa activity in patients the intensive care unit (ICU). The aim of study was to assess coagulation status ICU randomized receive enoxaparin either as a standard bolus (SCB) or continuous intravenous infusion (CII) for 3 consecutive days after initiation LMWH thromboprophylaxis.Thirty-eight were studied by conventional variables: prothrombin fragment F 1+2 (F 1+2) representing FXa inhibition and...
Abstract Introduction Platelet transfusions are frequently used in intensive care unit (ICU) patients, but contemporary epidemiological data sparse. We aim to present international on the use of platelet adult ICU patients with thrombocytopenia. Methods This is a protocol and statistical analysis plan for post hoc sub‐study 504 thrombocytopenic from ‘Thrombocytopenia patients: an inception cohort study (PLOT‐ICU)’. The primary outcome will be number receiving transfusion reported according...
SOCIETY OF CRITICAL CARE MEDICINE 34TH CONGRESS PHOENIX, ARIZONA, USA JANUARY 15-19, 2005: Poster Presentation: Epidemiology/Outcomes Research (Adult) IV