- Antibiotic Resistance in Bacteria
- 2D Materials and Applications
- Bacteriophages and microbial interactions
- Frailty in Older Adults
- Nanowire Synthesis and Applications
- Microgrid Control and Optimization
- Graphene research and applications
- Islanding Detection in Power Systems
- Perovskite Materials and Applications
- Cancer-related molecular mechanisms research
- Chronic Disease Management Strategies
- Genomics and Phylogenetic Studies
- Microbial infections and disease research
- Power System Optimization and Stability
- SARS-CoV-2 and COVID-19 Research
- Advanced Sensor and Energy Harvesting Materials
- Effects and risks of endocrine disrupting chemicals
- COVID-19 diagnosis using AI
- Balance, Gait, and Falls Prevention
- Ferroelectric and Negative Capacitance Devices
- HVDC Systems and Fault Protection
- Cancer Mechanisms and Therapy
- Cell death mechanisms and regulation
- Mechanical and Optical Resonators
- Circular RNAs in diseases
Central South University
2018-2025
Yichang Central People's Hospital
2020-2024
China Three Gorges University
2014-2024
Third Xiangya Hospital
2018-2024
Hunan University
2020-2023
Xiangya Hospital Central South University
2022
Changsha University
2020
2D Semiconductors are promising in the development of next-generation photodetectors. However, performances photodetectors largely limited by their poor light absorption (due to ultrathin thickness) and small detection range large bandgap). To overcome limitations, a strain-plasmonic coupled photodetector is designed mechanically integrating monolayer MoS2 on top prefabricated Au nanoparticle arrays. Within this structure, biaxial tensile strain can greatly reduce bandgap for broadband...
Abstract Van der Waals heterostructures (vdWHs) have attracted tremendous interest owing to the ability assemble diverse building blocks without constraints of lattice matching and processing compatibility. However, once assembled, fabricated vdWHs can hardly be separated into individual for further manipulation, mainly due technical difficulties in disassembling process. Here, we show a method disassemble as-fabricated blocks, which reassembled new with different device functionalities....
Two-dimensional (2D) semiconductors have attracted considerable attention in recent years. However, to date, there is still no effective approach produce large-scale monolayers while retaining their intrinsic properties. Here, we report a simple mechanical exfoliation method and high-quality 2D semiconductors, by designing an atomically flat Au-mesh film as the peeling tape. Using our prefabricated mesh tape, limited contact region (between crystal Au) could provide enough adhesion...
Abstract Memristors have attracted tremendous interest in the fields of high-density memory and neuromorphic computing. However, despite efforts that been devoted over recent years, high operating voltage, poor stability, large device variability remain key limitations for its practical application can be partially attributed to un-optimized interfaces between electrodes channel material. We demonstrate, first time, a van der Waals (vdW) memristor by physically sandwiching pre-fabricated...
Phage-antibiotic combination (PAC) therapy is a potential new alternative to treat infections caused by pathogenic bacteria, particularly those antibiotic-resistant bacteria. In the present study, phage YC#06 against highly multidrug-resistant Acinetobacter baumannii 4015 was isolated, identified, and characterized. Compared with antibiotics alone, time-kill experiments in vitro showed that antibiotic mixtures include chloramphenicol, imipenem, cefotaxime could produce phage-antibiotic...
Similar to the traditional synchronous generator (SG), a drawback of virtual (VSG) is active power oscillation, especially in system with parallel VSGs. In this paper, decentralized transient damping (DTD) control strategy proposed suppress oscillation during load fluctuations VSGs system, which based on embedding electromagnetic compensation and (TDPCP) into original VSG controller, providing two new degrees freedom for flexible regulation ratio without frequency measurement. way, can be...
Schottky diode is the fundamental building blocks for modern electronics and optoelectronics. Reducing semiconductor layer thickness could shrink vertical size of a diode, improving its speed integration density. Here, we demonstrate new approach to fabricate with ultrashort physical length approaching atomic limit. By mechanically laminating prefabricated metal electrodes on both-sides two-dimensional MoS2, intrinsic metal-semiconductor interfaces can be well retained. As result, thinnest...
ABSTRACT Phage-antibiotic combination treatment is a novel noteworthy drug delivery method in anti-infection. In the current study, we have isolated new phage, pB23, against carbapenem-resistant Acinetobacter baumannii 2023. Synergistic antibacterial effect between phage pB23 and meropenem could be more stable, using moderate doses of (multiplicity infection ranging from 0.1 to 1,000) based on results vitro activity. Phage effectively clear mature biofilms prevent biofilm formation . also...
Physical frailty is reversible, but little known about the sustainability of remission and its impact on dementia.
<title>Abstract</title> <bold>Background:</bold> Osteoporosis (OP) is a global health issue. Essential for the metabolism of bone, thyroid function plays crucial role. The connection between hypothyroidism and OP in individuals without cancer remains ambiguous. aim this study was to investigate impact on onset patients who did not have cancer. <bold>Methods:</bold> exposures with non-cancer were obtained from publicly accessible MRC-IEU consortium UK Biobank, while outcomes derived GWAS...
ObjectiveTo investigate the dynamic characteristics of serological antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is much current significance.MethodsThe changes and prevalence immunoglobulin M (IgM) G (IgG) SARS-CoV-2 were assessed from time symptom onset up to 210 days. Antibodies detected using a chemiluminescence immunoassay.ResultsThe average titers IgG/IgM positivity rates reached peak within 30 days then began decline continuously. Between 180...
Synergistic effects of phages in combination with antibiotics have received increasing attention. In this present study, we isolated a new phage pB3074 against clinically multidrug-resistant Acinetobacter baumannii. Phage combined cell wall-targeting could produce synergistic antibacterial effect vitro bactericidal activities. Further research indicates that the bacteriophage dose is critical to antimicrobial and antibiotic combination. Cefotaxime meropenem were selected as representative...
A microfluidic template method of fabricating nanowires with solution-processable semiconductors is demonstrated, which can be utilized for constructing nanowire-based devices.
Resistance to Adriamycin (ADR) is an increasing problem in the treatment of leukemia and development novel therapeutic strategies becoming increasingly important. Olaparib a poly (adenosine diphosphate‑ribose) polymerase (PARP) 1 inhibitor, which has promising antitumor activity patients with metastatic breast cancer germline BRCA mutations. Previously published studies have indicated that able overcome drug resistance cancer; however, its underlying mechanism action yet be elucidated. The...
Transient angle instability and fault overcurrent are two serious problems affecting the safe operation of virtual synchronous generator during grid faults. However, aspects mostly treated as independent in existing studies. In this article, taking both transient into consideration, a two-stage control collaboratively utilizing impedance (VI) switching PI is put forward. stage one, VI switched to boundary value determined by iteration algorithm avoid overcurrent. two, proportional loop or...
Abstract Background Rapid phage enumeration/quantitation and viable bacteria determination is critical for application treatment of infectious patients caused by the pathogenic bacteria. Methods In current study, a direct DNA detection-based Taqman qPCR methodology quantification P53 rapid ultrasensitive identification Acinetobacter baumannii ( A. ) was evaluated. Results The assay capable quantifying without extraction detection limit 550 PFU/mL. agreement bias between quantitative results...
Primary liver cancer is still the most common lethal malignancy. The N-myc downstream-regulated gene family (NDRG1-4) a group of multifunctional proteins associated with carcinogenesis. However, systematic evaluation diagnostic and prognostic values NDRG1 or NDRG2 expression in poorly investigated. matrix hepatocellular carcinoma (LIHC) was comprehensively analyzed by "limma" "Dseq2" R packages. Gene Ontology (GO) Set Enrichment Analysis (GSEA) were used to identify biological functional...
Objective: This study aims to determine the clinical significance of advanced lung cancer inflammation index (ALI) in predicting prognosis, chemotherapy response, and infection risk newly diagnosed multiple myeloma (MM) patients receiving induction therapy. Methods: A retrospective analysis characteristics laboratory data 111 MM from Haematology Department Third Xiangya Hospital Central South University January 2014 March 2020 was performed. We first determined relationship between ALI...