A5104262977- Energetic Materials and Combustion
- Oral Health Pathology and Treatment
- Intraocular Surgery and Lenses
- Rocket and propulsion systems research
- Plasma Diagnostics and Applications
- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Combustion and Detonation Processes
- Catalytic Processes in Materials Science
- Laser-induced spectroscopy and plasma
- Plasma Applications and Diagnostics
- Advanced Surface Polishing Techniques
- Head and Neck Cancer Studies
- Connexins and lens biology
- Genetic factors in colorectal cancer
- Head and Neck Surgical Oncology
- Advanced Machining and Optimization Techniques
- Radiopharmaceutical Chemistry and Applications
- Ocular Surface and Contact Lens
- Ferroptosis and cancer prognosis
- Yersinia bacterium, plague, ectoparasites research
- Salivary Gland Tumors Diagnosis and Treatment
- Autoimmune Bullous Skin Diseases
- Spectroscopy and Laser Applications
- Laser Design and Applications
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
2020-2024
Changsha Hospital for Maternal and Child Health Care
2024
Hunan University of Traditional Chinese Medicine
2024
Iowa State University
2016-2023
Guangdong Pharmaceutical University
2022-2023
State Key Laboratory of Gas Disaster Detecting, Preventing and Emergency Controlling
2022
Nanyang Medical College
2022
University of Chinese Academy of Sciences
2020
Sichuan Agricultural University
2020
Rice Research Institute
2020
Abstract Background While observational studies and experimental data suggest a link between oral lichen planus (OLP) cavity cancer (OCC), the causal relationship role of inflammatory cytokines remain unclear. Methods This study employed univariable multivariable Mendelian Randomization (MR) analysis to investigate OLP risk OCC. Additionally, potential in modulating this association was explored. Instrumental variables were derived from genetic variants associated with ( n = 377,277)...
Background Oral lichen planus (OLP) is a relatively common chronic T cell-mediated disease characterized by pain and inflammation. Clobetasol propionate (CLO) the first-line drug in treatment of OLP. The meta-analysis aimed to evaluate efficacy safety CLO for treating patients with Methods PubMed, Embase Web Science were systematically searched from database inception date up August 2023. There no restrictions on language or publication. outcomes our interest as follows: improvement clinical...
Objectives The objectives of this study are threefold: First is to perform a preliminary microarray analysis miRNA expression profile filter out differentially expressed in oral submucous fibrosis, second bioinformatics identify miRNA‐specific predicted genes, and third retrieve those miRNAs from literature account for the findings our investigations. Methods Buccal mucosa samples three clinically evident OSF patients normal volunteers were collected. Agilent Human experiments carried...
We studied the regulatory association of Porphyromonas gingivalis (PG) and cataracts. PCR FISH assays were used for detecting PG 16s ribosomal RNA genome, Immunofluorescence was expression RpgA in anterior capsular epithelium fibrosis markers subcapsular cataract (ASC) model. Flow cytometry reactive oxygen species apoptosis. deep sequencing is differential gene analysis. PG's positively 43.3% (101/233 cases) aqueous humor (AH) samples patients with cataracts, which differs from 4.7% (6/127)...
The dysregulation of CD5L has been reported in hepatocellular carcinoma (HCC). However, its functions HCC were controversial. In this study, we aimed to identify CD5L-associated pathways and markers explore their values diagnosis, prognosis treatment.HCC datasets with gene expression profiles clinical data TCGA ICGC downloaded. immune/stroma cell infiltrations estimated xCell. genes (CD5L-AGs) identified comparisons set enrichment analysis (GSEA). Cox regression, Kaplan-Meier survival...
This effort explores the microwave-supported plasma enhancement of a composite solid propellant flame through novel alkali metal doping technique. The technique enables formation high temperature within in order to perturb burning rate propellant. aim this is investigate use combined with an earth produce unsteady features combustion aluminized employs targeted energy deposition from subcritical microwave field flame-induced ionization atom (i.e. sodium, form sodium nitrate, NaNO3) and free...
Purpose: Arecoline is one of the main toxic components arecoline to cause oral mucosal lesions or canceration, which seriously affects survival and life quality patients. This study analyzed mechanism Jiawei Danxuan Koukang (JDK) in alleviating induced lesions, provide new insights for treatment submucosal fibrosis (OSF) cancerosis. Methods: Metabolomics was applied analyze composition JDK serum metabolites. The active ingredients were by combined ultra-high performance liquid chromatography...
Background and Objective. Oral submucous fibrosis (OSF) is a progressive irreversible disorder of collagen metabolism, resulting in mucosal fibrosis, oral functional changes, even malignant transformation. This study investigated the relationship between human leukocyte antigen (HLA)-DQB1 alleles susceptibility to OSF Hunan Han population, providing new basis for clinical prevention treatment OSF. Methods. 44 patients healthy volunteers were included this study. To detect expression...
To investigate the effect of 131I-labeled high-affinity peptides Caerin 1.1 and 1.9 for treatment A549 human NSCLC cells.① 3-[4,5-Dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) plate clone formation assays were performed to confirm in vitro anti-tumor activity 1.9. ② Chloramine-T was used label with 131I, Cell Counting Kit 8 assay analyze inhibitory unlabeled 1.1, 1.9, on proliferation cells. An nude mouse model established vivo 1.9.① inhibited cells a concentration-dependent...
The aim of this study was to analyze and compare the therapeutic effects 131I-caerin 1.1 131I-c(RGD)2 on TE-1 esophageal cancer cell xenografts.(1) in vitro antitumor polypeptides caerin c(RGD)2 were verified by MTT clonogenic assays. prepared chloramine-T (Ch-T) direct labeling, their basic properties measured. binding elution 1.1, 131I-c(RGD)2, Na131I (control group) cells studied through (2) antiproliferative effect cytotoxicity Na131I, detected Cell Counting Kit-8 (CCK-8) assay. (3) A...
Mutations in GJA8 are associated with hereditary autosomal dominant and recessive cataract formation. In this study, a novel insert mutation was identified Chinese congenital family cosegregated the disease pedigree. This introduces five additional amino acid residues YAVHY after histidine at 95 site (p.H95_A96insYAVHY) within second transmembrane (TM2) domain of Cx50 protein (Cx50-insert). Ectopic expression Cx50-insert impairs hemichannel functions gap junction activity compared to...
Natural diamond can be cut and grinded for manufacturing the super-hard tool in field of ultraprecision machining.But natural cutting technology with high precision quality is still a challenge.The idea that laser method combined other technologies provides new try cutting.In this paper, water jet-guided (WJL) used to along crystal plane (111) manufacture, surfaces are observed by using optical microscope, profiler Xray diffractometer analyze difference between two methods WJL.From analyzed...
To investigate the genetic mutations that are associated hereditary autosomal dominant cataract in a Chinese family.A family consisting of 20 patients (including 9 male and 11 female) 2 unaffected individuals from 5 generations were diagnosed to be typical pedigree. Genomic DNA samples extracted peripheral blood cells participants this Exon sequence was used for mutation screening. In silico analysis study structure characteristics connexin 46 (CX46) mutant. Immunoblotting conduceted testing...
Alkali metals are prevalent in coal combustion, biomass thermal conversion to fuels, and energetic material have applications as dopants for combustion diagnostics plasma-based control. Recently, the dynamic control of propellant burning rate pyrotechnic luminosity been demonstrated through combined microwave field radiation incorporation alkali dopants. Understanding distribution within flame is essential predicting field–flame interaction. However, multiphase environment exhibits...
To study the performance of pure aluminium (Al) oxide film produced by high-speed wire electrical discharge machining (WEDM-HS), some characterisation indices including phase composition, surface morphology characteristics, roughness, friction coefficient, content and thickness 1060 Al are researched, respectively, through X-ray diffraction, energy dispersive spectroscopy, scanning electron microscope, confocal contourgraph nanoindentation. The results show that is mainly composed Al2O3...