A5078836107- Renal cell carcinoma treatment
- Bladder and Urothelial Cancer Treatments
- Renal and related cancers
- Prostate Cancer Treatment and Research
- Urinary and Genital Oncology Studies
- Prostate Cancer Diagnosis and Treatment
- Urological Disorders and Treatments
- Cancer Immunotherapy and Biomarkers
- Urologic and reproductive health conditions
- Multiple and Secondary Primary Cancers
- Gene expression and cancer classification
- Fungal and yeast genetics research
- Hormonal and reproductive studies
- Sexual Differentiation and Disorders
- Acute Myeloid Leukemia Research
- Renal and Vascular Pathologies
- Ureteral procedures and complications
- Retinoids in leukemia and cellular processes
- Genomics and Phylogenetic Studies
- Microbial Natural Products and Biosynthesis
- Protein Kinase Regulation and GTPase Signaling
- Testicular diseases and treatments
- Cardiac tumors and thrombi
- Fire dynamics and safety research
- Combustion and flame dynamics
Nagoya University
2004-2024
Joint Genome Institute
2024
Lawrence Berkeley National Laboratory
2024
Nara City Hospital
2015
National Maritime Research Institute
2014
Kobe City Medical Center General Hospital
1999-2007
Tohoku University
2007
Graduate School USA
2005
RIKEN Center for Computational Science
2005
The University of Tokyo
2005
A murine transcription factor, PEBP2, is composed of two subunits, alpha and beta. There are genes in the mouse genome, PEBP2 B, which encode subunit. Two types B cDNA clones, B1 B2, were isolated from fibroblasts characterized. They found to represent 3.8- 7.9-kb transcripts, respectively. The 3.8-kb RNA encodes previously described protein referred as B1, while a 387-amino-acid protein, termed identical except that it has an internal deletion 64 amino acid residues. Both B2 associate with...
The androgen receptor (AR) gene has a polymorphic CAG microsatellite encoding variable-length glutamine repeats in the AR protein. purpose of this study was to evaluate association between growth benign prostatic hyperplasia (BPH) and repeat length.We determined lengths 176 BPH patients who underwent simple prostatectomy 41 control subjects without enlargement (non-BPE group).A statistically significant (P < 0.02) trend for large adenoma size with short length found among quartiles. fourth...
DNA-binding transcription factors are broadly characterized as proteins that bind to specific sequences within genomic DNA and modulate the expression of downstream genes. This study focused on KojR, a factor involved in metabolism kojic acid, which is an organic acid synthesized
A murine transcription factor, PEBP2, is composed of two subunits, alpha and beta. There are genes in the mouse genome, PEBP2 B, which encode subunit. Two types B cDNA clones, B1 B2, were isolated from fibroblasts characterized. They found to represent 3.8- 7.9-kb transcripts, respectively. The 3.8-kb RNA encodes previously described protein referred as B1, while a 387-amino-acid protein, termed identical except that it has an internal deletion 64 amino acid residues. Both B2 associate with...
DNA-binding transcription factors are broadly characterized as proteins that bind to specific sequences within genomic DNA and modulate the expression of downstream genes. This study focused on KojR—a factor involved in metabolism kojic acid, which is an organic acid synthesized Aspergillus oryzae known for its tyrosinase-inhibitory properties. However, regulatory mechanism underlying KojR-mediated synthesis remains unclear. Hence, we aimed obtain a comprehensive identification...
No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Dec 1999SERUM C-REACTIVE PROTEIN LEVEL AND THE IMPACT OF CYTOREDUCTIVE SURGERY IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA KEITA FUJIKAWA, YOSHIYUKI MATSUI, HIROYA OKA, SHIGEKI FUKUZAWA, and HIDEO TAKEUCHI FUJIKAWAKEITA FUJIKAWA More articles by this author , MATSUIYOSHIYUKI MATSUI OKAHIROYA OKA FUKUZAWASHIGEKI FUKUZAWA TAKEUCHIHIDEO View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)68072-XAboutFull TextPDF...
Abstract Primary soft tissue sarcoma of the adrenal gland is very rare and aggressive. In right tumors, because direct venous drainage into inferior vena cava, tumor may invade caval wall toward atrium. We present a case leiomyosarcoma extending
No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Sep 2000SERUM IMMUNOSUPPRESSIVE ACIDIC PROTEIN AND NATURAL KILLER CELL ACTIVITY IN PATIENTS WITH METASTATIC RENAL CARCINOMA BEFORE AFTER NEPHRECTOMY KEITA FUJIKAWA, YOSHIYUKI MATSUI, KATSUKI MIURA, TAKASHI KOBAYASHI, HIROYA OKA, SHIGEKI FUKUZAWA, and HIDEO TAKEUCHI FUJIKAWAKEITA FUJIKAWA , MATSUIYOSHIYUKI MATSUI MIURAKATSUKI MIURA KOBAYASHITAKASHI KOBAYASHI OKAHIROYA OKA FUKUZAWASHIGEKI FUKUZAWA TAKEUCHIHIDEO View All Author...
Abstract Background: Patients with non‐invasive (Ta/T1) transitional cell carcinoma (TCC) of the urinary bladder are often observed without progression in long‐term follow‐up period, although many them experience recurrence disease. It is difficult to accurately predict disease outcome each patient Ta/T1 TCC using conventional prognostic criteria. In this study, we examined usefulness artificial neural networks (ANNs) patients bladder. Methods: A retrospective, study 90 bladder, diagnosed by...
DNA-binding transcription factors (TFs) play a central role in transcriptional regulation mechanisms, mainly through their specific binding to target sites on the genome and of expression downstream genes. Therefore, comprehensive analysis function these TFs will lead understanding various biological mechanisms. However, functions
To clarify the aspects affected by PEBP2β/MYH11 fusion gene involved in inv(16), we analysed immunophenotypes myelomonoblastic leukaemias. We found high expressions of CD34 and c‐KIT antigens cells from all patients carrying this gene, including two with M4 one CML blastic phase, contrast to those without gene. These findings indicate that immunophenotyping is useful for detecting a leukaemia leukaemias immature expressing antigens.
Transcription factors (TFs) specifically bind to DNA sequences and control the expression of target genes. AoXlnR is a key TF involved in xylanolytic cellulolytic enzymes filamentous fungi, Aspergillus oryzae. Genomic SELEX-Seq (gSELEX-Seq) can reveal vitro binding sites genome. To date, gene network controlled by A. oryzae not fully explored. In this study, data from gSELEX-Seq analysis mining were applied toward comprehensive investigation AoXlnR-regulated transcriptional Around 2000...
No AccessJournal of UrologyCLINICAL UROLOGY: Case Reports1 May 2000A CASE OF RENAL CELL CARCINOMA DURING PREGNANCY: SIMULTANEOUS CESAREAN SECTION AND RADICAL NEPHRECTOMY TAKASHI KOBAYASHI, SHIGEKI FUKUZAWA, KATSUKI MIURA, YOSHIYUKI MATSUI, KEITA FUJIKAWA, HIROYA OKA, and HIDEO TAKEUCHI KOBAYASHITAKASHI KOBAYASHI More articles by this author , FUKUZAWASHIGEKI FUKUZAWA MIURAKATSUKI MIURA MATSUIYOSHIYUKI MATSUI FUJIKAWAKEITA FUJIKAWA OKAHIROYA OKA TAKEUCHIHIDEO View All Author...
Abstract Post‐operative chyloretroperitoneum is a rare complication in urological surgery. We experienced two cases of post‐operative following retroperitoneoscopic left nephroureterectomy. Both were treated successfully with drainage, low fat diet, total parenteral nutrition (case 1 only), sclerotherapy and somatostatin analog. Laparoscopic procedures are supposed to have higher risk chylous complications, as CO 2 pressure appears make the operator overlook suppressing lymphatic leakage...
Abstract Aim: The 41‐ and 43‐kDa mitogen‐activated protein kinases (MAPK; ERK2 ERK1, respectively) play pivotal roles in the mitogenic signal transduction pathway. We previously demonstrated that constitutive activation of MAPK cascade was related to carcinogenesis human tumors. In this study, we examined whether progression androgen independence prostate cancer. Methods: by appearance phosphorylated forms an vitro kinase assay four (androgen‐dependent independent) cancer cell lines rat line...
Abstract A rare case is reported of a fistula between the left internal iliac artery and ureter in patient whose kidney was only functioning kidney. Internal embolization initially successful stopping bleeding, but recurred when ureteral stent removed. Even after embolization, tissue surrounding remains very fragile, so may easily recur as result slight injury or inflammation.
The indications of partial nephrectomy have expanded after the introduction new techniques for preventing excessive blood loss and avoiding deterioration renal function clamping pedicle. We present our clinical experience tumors using a microwave tissue coagulator.Between April 1996 January 2000, 34 patients underwent open nephrectomies in Kobe City General Hospital. coagulator was used resection parenchyma, but deeper lesions sharp dissection performed. Twenty-two (groups 1 2) without...
Epigenetic alterations such as genomic imprinting might play an important role in human tumorigenesis, addition to specific genetic alterations. To clarify the of and/or epigenetic tumorigenesis testicular germ cell tumors (GCTs), we analyzed 40 primary and 3 metastatic GCTs with regard chromosomal losses their parental origin. A high incidence loss heterozygosity (LOH) was demonstrated on chromosomes 1p, 3p, 11p, 17p: 9/19 (47%), 18/39 (46%), 13/40 (33%) 20/36 (56%), respectively. However,...