Megumi Hori

ORCID: 0009-0007-9167-6039
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About
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Research Areas
  • Health, Environment, Cognitive Aging
  • Global Cancer Incidence and Screening
  • Health Systems, Economic Evaluations, Quality of Life
  • Multiple and Secondary Primary Cancers
  • Cancer Risks and Factors
  • Air Quality and Health Impacts
  • Colorectal Cancer Screening and Detection
  • Nutritional Studies and Diet
  • Gastric Cancer Management and Outcomes
  • Advanced Causal Inference Techniques
  • Urban Transport and Accessibility
  • Human Mobility and Location-Based Analysis
  • Smoking Behavior and Cessation
  • Esophageal Cancer Research and Treatment
  • COVID-19 epidemiological studies
  • Lung Cancer Treatments and Mutations
  • Thermal Regulation in Medicine
  • Colorectal Cancer Treatments and Studies
  • Cutaneous Melanoma Detection and Management
  • Bladder and Urothelial Cancer Treatments
  • Transportation Planning and Optimization
  • Climate Change and Health Impacts
  • Data-Driven Disease Surveillance
  • Cervical Cancer and HPV Research
  • Childhood Cancer Survivors' Quality of Life

University of Shizuoka
2022-2025

Shizuoka University
2022

Azabu University
2021

RIKEN Center for Biosystems Dynamics Research
2021

Ghent University
2021

Kyoto University Institute for Chemical Research
2019

Kyoto University
2019

Nagoya Institute of Technology
2017

Nagoya University
2007-2016

National Cancer Center
2016

The Japan Cancer Surveillance Research Group aimed to estimate the cancer incidence in 2009 based on data collected from 32 of 37 population-based registries, as part Monitoring Incidence (MCIJ) project. only primary invasive for was estimated be 775 601. Stomach and breast were leading types males females, respectively.

10.1093/jjco/hyv088 article EN Japanese Journal of Clinical Oncology 2015-07-03

The analysis of cancer trends in Japan requires periodic updating. Herein, we present a comprehensive report on the incidence and mortality using recent population-based data. National data between 1958 2013 were obtained from published vital statistics. Cancer 1985 2010 high-quality registries three prefectures (Yamagata, Fukui Nagasaki). Joinpoint regression was performed to examine age-standardized rates mortality. All-cancer decreased mid-1990s, with an annual percent change −1.3% (95%...

10.1093/jjco/hyv002 article EN Japanese Journal of Clinical Oncology 2015-01-30

Background: Unlike many North American and European countries, Japan has observed a continuous increase in cancer incidence over the last few decades. We examined most recent trends population-based mortality Japan.

10.2188/jea.je20200416 article EN cc-by Journal of Epidemiology 2021-02-05

Little is known about cancer incidence among children and youths in Japan. We aimed to describe Japan focusing on childhood, adolescence young adulthood (AYA). Cancer data were obtained from the Monitoring of Incidence project. For 2009–2011 incidence, collected 40 prefectures, which 27 prefectures meeting quality standards analyzed (population coverage: 38.6%). Cancers diagnosed 0–39 years age classified according International Classification Childhood (version 3). Crude rates (including...

10.1093/jjco/hyx070 article EN cc-by-nc Japanese Journal of Clinical Oncology 2017-05-08

Most patients suffering from cancer die of metastatic disease. Surgical removal solid tumors is performed as an initial attempt to cure patients; however, surgery often accompanied with trauma, which can promote early recurrence by provoking detachment tumor cells into the blood stream or inducing systemic inflammation both. We have previously reported that administration atrial natriuretic peptide (ANP) during perioperative period reduces inflammatory response and has a prophylactic effect...

10.1073/pnas.1417273112 article EN Proceedings of the National Academy of Sciences 2015-03-16

In this retrospective study, we aimed to clarify the risk of developing a second primary cancer and determine periods high cancers. Subjects were all patients who had been diagnosed with first registered Nagasaki Prefecture Cancer Registry between 1985 2007. We calculated standardized incidence ratio (SIR) according site years after diagnosis cancer. A developed in 14 167 174 477 subjects (8.1%) during median follow-up 1.8 years. The SIR was 1.10 (95% confidence interval, 1.08-1.11). Some...

10.1111/cas.12433 article EN cc-by-nc-nd Cancer Science 2014-05-11

Colorectal cancer (CRC) is globally one of the most common cancers. Although studies have found a significant prognostic impact location for right-sided colon cancers compared with those left-side, evidence lacking in Japanese population. Therefore, we investigated 5-year net survival by tumor site population.Diagnoses obtained between 2006 and 2008 21 population-based registries from Monitoring Cancer Incidence Japan (MCIJ) project were used. Colon patients categorized as having...

10.1186/s12885-019-5644-y article EN cc-by BMC Cancer 2019-05-09

ABSTRACT Despite the importance of genetic testing for risk assessment and treatment in breast cancer, prognostic impact germline pathogenic variants (PVs), especially Asian populations, is unclear. We assessed PVs patients with early‐stage cancer. This study included 7278 Japanese multihospital registry patients. ATM , BRCA1 BRCA2 CDH1 CHEK2 NBN NF1 PALB2 PTEN STK11 TP53 were evaluated. PV non‐PV carriers matched by age, histology, stage. Associations between survival assessed. The primary...

10.1111/cas.70002 article EN cc-by-nc Cancer Science 2025-02-10

ABSTRACT While male breast cancer (MBC) remains a rare and understudied disease, comparatively little is known about its prognosis in contrast to female (FBC). There paucity of large population‐based studies comparing the MBC patients FBC Japan. This study analyzed 181,540 cases, 1058 (0.6%) males 180,482 (99.4%) females, from 12 prefectures Japan diagnosed between 1993 2011. Five‐ ten‐year net survival (NS) were estimated stratified by sex, period, age, stage, histological groups. Excess...

10.1111/cas.70068 article EN cc-by-nc Cancer Science 2025-03-31

The This study estimated the cancer burden attributable to modifiable factors in Japan 2015 using best available epidemiological evidence and a standard methodology. We selected following for inclusion estimates, namely tobacco smoking (active secondhand smoking), alcohol drinking, excess bodyweight, physical inactivity, infectious agents (

10.35772/ghm.2021.01037 article EN Global Health & Medicine 2021-12-29

Cancer in children, adolescents, and young adults (AYAs) although rare, is the leading disease-specific cause of death Japan. This study aims to investigate cancer incidence type treatment hospital among children AYAs data (2016-2018) for those aged 0-39 years were obtained from Japanese population-based National Registry. types classified according 2017 update International Classification Childhood (Third Edition), AYA Site Recode 2020 Revision. Cases also categorized into three groups:...

10.1111/cas.15892 article EN cc-by-nc Cancer Science 2023-07-06

Continued decrease in smoking prevalence and increasing use of sensitive diagnostic procedures necessitate updated monitoring trends lung cancer incidence Japan. We analyzed histology- stage-specific 1993 to 2015 using data from 62 870 diagnosed cases the Monitoring Cancer Incidence Japan project. After applying a multiple imputation approach impute missing/unknown values stage histology, we estimated age-standardized rates applied joinpoint regression analyses. observed long-term growth...

10.1002/ijc.33962 article EN cc-by International Journal of Cancer 2022-02-09

To estimate cumulative incidence and mortality risk for gastric cancer by category.Risk was classified into four types according to the presence/absence of Helicobacter pylori infection chronic atrophic gastritis: in order lowest highest risk, Group A: H. pylori(-) gastritis(-); B: pylori(+) C:H. gastritis(+); and, D: gastritis(+). We used vital statistics crude all-cause rates 2011 data from population-based registries (the Monitoring Cancer Incidence Japan) 2011. For relative prevalence,...

10.1093/jjco/hyx128 article EN cc-by-nc Japanese Journal of Clinical Oncology 2017-08-23

Abstract Background: We provide comprehensive sex-stratified projections of cancer prevalence for 22 sites in Japan from 2020 to 2050. Methods: Using a scenario-based approach, we projected by combining incidence cases and survival probabilities. Age-specific incidences were forecasted using age–period–cohort models, while rates estimated period-analysis approach multiple parametric models. To understand changes prevalence, decomposition analysis was conducted, assessing the contributions...

10.1158/1055-9965.epi-23-0754 article EN cc-by-nc-nd Cancer Epidemiology Biomarkers & Prevention 2023-09-27

Two p-type semiconducting donor-acceptor polymers were designed and synthesized for use in organic solar cells. The combine a benzodithiophene (BDT) donor thiazole-fused benzothiadiazole (TzBT) acceptor. TzBT acceptor units are compared, one with an alkylthio group (P1) the other more strongly electron-withdrawing alkylsulfonyl (P2) at fused thiazole ring. electron-accepting nature of unit lowers lowest unoccupied molecular orbital (LUMO) energy P1 P2 relative to that BT analog (PBDT-BT),...

10.1039/c9ra00229d article EN cc-by-nc RSC Advances 2019-01-01

Abstract Background: This study aimed to assess long-term trends in the incidence of prostate cancer by stage at diagnosis before and after introduction population-based PSA screening. Methods: We used data from three registries Japan. A total 29,458 malignant cases diagnosed between 1993 2014 were for analysis. Multiple imputation with chained equations was impute a specific “unknown” missing status. estimated age-standardized rates 2014, joinpoint linear regression models changes trend....

10.1158/1055-9965.epi-19-1228 article EN Cancer Epidemiology Biomarkers & Prevention 2020-03-13

Advances in diagnostic techniques and treatment modalities have impacted head neck cancer (HNC) prognosis, but their effects on subsite-specific prognosis remain unclear. This study aimed to assess trends mid- long-term survival for HNC patients diagnosed from 1993 2011 using data population-based registries Japan. We estimated the net (NS) by subsite 13 prefectural Changes over time were assessed multivariate excess hazard model of mortality. In total, 68,312 included this analysis....

10.1111/cas.16028 article EN cc-by-nc Cancer Science 2023-11-23

Abstract Recent advances in treating colorectal cancer (CRC) have increased the importance of multidisciplinary treatment. This study aimed to clarify trends treatment and survival CRC using population‐based registry data Japan. We analyzed cases diagnosed from 1995 through 2015 a six prefectures. The year diagnosis was classified into five periods, detailed categorization treatments were identified. calculated net excess hazard death on 256,590 patients. use laparoscopic surgery has been...

10.1111/cas.16210 article EN cc-by-nc Cancer Science 2024-05-07

Three kinds of survival rates are generally used depending on the purpose investigation: overall, cause-specific, and relative. The differences among these 3 derived from their respective formulas; however, reports based actual cancer registry data few because incomplete information short follow-up duration recorded registration. aim this study was to numerically visually compare basis Nagasaki Prefecture Cancer Registry. Subjects were patients diagnosed with registered in between 1999 2003....

10.7314/apjcp.2012.13.11.5681 article EN cc-by Asian Pacific Journal of Cancer Prevention 2012-11-30

We compared resistive heating (RH) and upper-body convective warming (CW) in 70 patients (RH 33, CW 31, 6 excluded) undergoing major abdominal surgery. The effect of RH was not inferior to that for the time-weighted average core temperature, lower limit 95% greater than −0.5°C. Resistive showed no inferiority maintaining temperature with warming.

10.1177/175045891302300404 article EN Journal of Perioperative Practice 2013-04-01

Tobacco is the greatest single cause of many non-communicable diseases, including cancer. We calculated proportion cancer incidence and mortality in 2015 attributable to tobacco smoking exposure secondhand smoke (SHS). Data on prevalence active were derived from 2005 Japanese National Health Nutrition Survey by age group gender. For SHS prevalence, data a nationwide cross-sectional survey 2004-2005 used. Based standard formulas, population fractions (PAFs) for each causally associated with...

10.35772/ghmo.2021.01013 article EN GHM Open 2021-12-10

While esophageal squamous cell carcinoma (ESCC) is the predominant histological type in Japan, concern has been expressed over an increase proportion of adenocarcinoma (EAC), especially middle-aged populations. This study aimed to assess long-term trends cancer incidence by type.We used data from three population-based registries Japan with 10,642 cases diagnosed between 1993 and 2014. The multiple imputation approach was impute a specific (ESCC, EAC, others) for "Unknown" or missing status....

10.1002/cam4.4528 article EN Cancer Medicine 2022-01-25
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