A5023215047- Atrial Fibrillation Management and Outcomes
- Peripheral Artery Disease Management
- Coronary Interventions and Diagnostics
- Acute Ischemic Stroke Management
- Cardiac Imaging and Diagnostics
- Inflammasome and immune disorders
- Cardiovascular Disease and Adiposity
- Intracerebral and Subarachnoid Hemorrhage Research
- Blood Pressure and Hypertension Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Organ Transplantation Techniques and Outcomes
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Function and Risk Factors
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Cerebrovascular and Carotid Artery Diseases
- Heart Failure Treatment and Management
- Radiation Dose and Imaging
- Vitamin C and Antioxidants Research
- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Lipoproteins and Cardiovascular Health
- Heme Oxygenase-1 and Carbon Monoxide
- Bariatric Surgery and Outcomes
- Vasculitis and related conditions
Ark Medical Center
2023-2025
West Virginia University Hospitals
2025
University of Louisville
2021-2024
West Virginia University
2024
The Wright Center for Graduate Medical Education
2024
Wayne State University
2024
Detroit Medical Center
2024
Dow University of Health Sciences
2024
SUNY Cortland
2024
Carle Foundation Hospital
2024
In exploring therapeutic options for ischemic heart disease (IHD) and failure, cell-based cardiac repair has gained prominence. This systematic review delves into the current state of knowledge surrounding therapies repair. Employing a comprehensive search across relevant databases, study identifies 35 included studies with diverse cell types methodologies. Encouragingly, these findings reveal promise in repair, demonstrating significant enhancements left ventricular ejection fraction (LVEF)...
Heme oxygenase-1 (HO-1) is one of the most powerful cytoprotective proteins known. The goal this study was to explore effects HO-1 in c-kit-positive cardiac cells (CPCs). LinNEG/c-kitPOS CPCs were isolated and expanded from wild-type (WT), transgenic (TG), or knockout (KO) mouse hearts. Compared with WT CPCs, cell proliferation significantly increased HO-1TG decreased HO-1KO CPCs. also exhibited a marked increase new DNA synthesis during S-phase division, not only under normoxia (21% O2) but...
Madam, Domperidone is used in the treatment of nausea and vomiting as an antiemetic prokinetic drug. Its pro-kinetic effects mainly manifest upper gastrointestinal tract by acting a dopamine receptor antagonist [1]. However, drug has been banned FDA USA due to its association with cardiac arrhythmias arrest. A recent meta-analysis shown statistically significant between sudden death [2] use domperidone which raises question usage Pakistan over-the-counter medication. The considers six...
Background: Cardiovascular outcomes in patients with giant cell arteritis (GCA) compared to non-GCA remain a significant concern due the inflammatory nature of GCA and its potential impact on cardiovascular health. We conducted first meta-analysis kind compare events versus populations. Methods: A was studies comparing between cohorts. The analysis focused three outcomes: major (MACE), cerebrovascular accidents, including stroke or hemorrhage (CVA), myocardial infarction (MI). provided odds...
Background: Midodrine, an FDA-approved peripheral alpha1-adrenergic agonist for treating orthostatic hypotension, is also used off-label to manage hypotension in patients with advanced heart failure (HF). Hypotension, whether due HF itself or as a side effect of its treatment, often restricts the optimization medical therapy these patients. By increasing baseline blood pressure, midodrine can enhance tolerance medications, potentially improving patient outcomes. The use limited risk supine...
e24003 Background: Cancer patients undergoing chemotherapy suffer from a variable degree of cancer therapy–related cardiac dysfunction and heart failure (HF). It is known that sodium glucose co-transporter 2 (SGLT2) inhibitors improve outcomes in with HF independent diabetes mellitus left ventricular ejection fraction; our study aims to investigate the potential benefits SGLT2 inhibitory therapy specifically chemotherapy. Methods: We performed an electronic search on PubMed, Embase,...
12022 Background: Cancer screenings, particularly mammography, are crucial in early detection and management of breast cancer, the most common cancer among women worldwide. Despite advances, disparities persist outcomes cardiovascular health, highlighting need for an integrative approach to care. Methods: We conducted a retrospective cohort analysis 22,118 female patients over 40 years age diagnosed with arterial calcification (BAC) on mammography using TriNetX database. Each patient BAC was...