A5085335313- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- RNA Research and Splicing
- Cancer-related gene regulation
- Respiratory viral infections research
- Epigenetics and DNA Methylation
- Tracheal and airway disorders
- Wnt/β-catenin signaling in development and cancer
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Ischemia and Reperfusion
- Viral-associated cancers and disorders
- Aquaculture Nutrition and Growth
- Kruppel-like factors research
- RNA and protein synthesis mechanisms
- Immune Cell Function and Interaction
- Aquaculture disease management and microbiota
- Polyomavirus and related diseases
- Lymphoma Diagnosis and Treatment
- Molecular Biology Techniques and Applications
- Trauma and Emergency Care Studies
- MicroRNA in disease regulation
- COVID-19 diagnosis using AI
- Cardiovascular Function and Risk Factors
- Traumatic Brain Injury Research
- Antenna Design and Analysis
First Affiliated Hospital of Fujian Medical University
2018-2024
Fujian Medical University
2018-2024
Fujian Provincial Hospital
2023
Israel National Institute for Health Policy Research
2018
City Of Hope National Medical Center
2013
City of Hope
2013
Beckman Research Institute
2013
Temasek Life Sciences Laboratory
2013
National University of Singapore
2013
Shantou University
2010
Identification of differentially expressed genes (DEGs) and regulated pathways in response to stressors using a whole-genome approach is critical understanding the mechanisms underlying stress responses. We challenged Asian seabass with lipopolysaccharide (LPS), Vibrio harveyi, high salinity fasting, sequenced six cDNA libraries intestine samples Roche 454 RNA-seq. Over 1 million reads (average size: 516 bp) were obtained. The de novo assembly obtained 83 911 unisequences an average length...
Head and Neck Squamous Cell Carcinoma (HNSCC) is a malignancy characterized by high incidence recurrence rate. 5-methylcytosine (m
Alternative splicing (AS) is an important mechanism responsible for the production of protein diversity. Increasing evidence has suggested that out-of-control alternative closely related to genesis and development cancer. Genome-wide analysis on head neck squamous cell carcinoma (HNSCC) not been systemically studied, so remains at preliminary stage requires further studies by researchers. In this study, systemic bioinformatic was carried out genome-wide events 498 clinical HNSCC samples from...
Programmed cell death 4 (PDCD4) is decreased in many different kinds of malignant tumors. EMT endows tumor cells invasive and metastatic properties. However, few studies have determined the role PDCD4 regulation context laryngeal carcinoma. We examined relationship between EMT-associated proteins E-cadherin N-cadherin using carcinoma tissues. Gene manipulation was used to define regulatory capacity PDCD4. report that E-cadherin/N-cadherin expression were significantly changed tissues, their...
Abstract Background Airway bleeding events are a rare incident in SARS-CoV-2 -infected patients after tracheostomies. We aimed to explore the correlation between airway and infection evaluate consistency of RNA test results upper lower samples from Methods Forty-four temporary or permanent tracheostomy were divided into positive group (29 patients) negative (15 based on their oropharyngeal swabs. The tracheal swabs re-collected for detection. Demographic clinical characteristics recorded all...
Laryngeal cancer (LC), a highly fatal tumor in the head and neck region, has been focus of research recent years. The study LC primarily focused on role long non-coding RNAs (lncRNAs) regulating gene expression, as they have emerged pivotal factors this biological process. Additionally, reversible RNA modification called N6-methyladenosine (m6A) observed to significant impact expression well. purpose is investigate m6A-related lncRNAs prognosis laryngeal squamous cell carcinoma (LSCC)....
Background: In 2007, Gaynor et al. discovered a previously unidentified human polyomavirus in respiratory secretions obtained from patients with symptoms of acute tract infection. T his new virus was designated WU polyomavirus.To investigate the frequency it infections GuangDong, China, We sought to describe detection and clinical characterization Polyomavirus infection Children. Methods: From July 2008 through June 2009, nasopharyngeal aspirates were collected 771 child ren who hospitalized...
头颈部鳞癌包括口腔颌面部肿瘤、喉癌、甲状腺癌、鼻咽癌等，是世界上常见恶性肿瘤之一。迄今确切的病因尚不清楚，可能是吸烟、饮酒、病毒感染等多种因素综合所致。尽管目前诊断手段、手术治疗及化疗水平比过去几十年都有提高，但头颈肿瘤5年的生存率仍然在50%左右。有文献报道，MicroRNA（miRNA）在多种人类肿瘤细胞中异常表达，并且参与调节肿瘤细胞的增殖、分化及凋亡等多个生物学过程，其突变、缺失或表达水平的异常与人类肿瘤的发生、发展密切相关。