A5017591364- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Congenital Heart Disease Studies
- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Cardiac Arrest and Resuscitation
- Cardiovascular Conditions and Treatments
- Clinical Nutrition and Gastroenterology
- Pregnancy and preeclampsia studies
- Epilepsy research and treatment
- Maternal and Perinatal Health Interventions
- Global Maternal and Child Health
- Neuroscience of respiration and sleep
- Tracheal and airway disorders
- Esophageal and GI Pathology
- Child and Adolescent Health
- Traumatic Brain Injury and Neurovascular Disturbances
- Prenatal Screening and Diagnostics
- Hemodynamic Monitoring and Therapy
- Non-Invasive Vital Sign Monitoring
- Preterm Birth and Chorioamnionitis
- Mechanical Circulatory Support Devices
- Birth, Development, and Health
The University of Melbourne
2010-2024
Mercy Hospital for Women
2007-2024
King Edward Memorial Hospital
2023
Heidelberg University
2016
Royal Women's Hospital
2007
Murdoch Children's Research Institute
2001
Studies in animals and humans have suggested that docosahexaenoic acid (DHA), an n-3 long-chain polyunsaturated fatty acid, might reduce the risk of bronchopulmonary dysplasia, but appropriately designed trials are lacking.We randomly assigned 1273 infants born before 29 weeks gestation (stratified according to sex, gestational age [<27 or 27 <29 weeks], center) within 3 days after their first enteral feeding receive either emulsion providing DHA at a dose 60 mg per kilogram body weight day...
Abstract Objective To study the epilepsy syndromes among severe epilepsies of infancy and assess their incidence, etiologies, outcomes. Methods A population‐based cohort was undertaken with onset before age 18 months in Victoria, Australia. Two epileptologists reviewed clinical features, seizure videos, electroencephalograms to diagnose International League Against Epilepsy syndromes. Incidence, outcomes at 2 years were determined. Results Seventy‐three 114 (64%) infants fulfilled diagnostic...
Safe and effective functioning of nasogastric orogastric tubes in the neonatal intensive care unit (NICU) is achieved by ensuring their correct placement within stomach. Insertion length has traditionally been estimated using morphological measures, but studies have indicated that these are frequently inaccurate. This study aimed to evaluate frequency tube determine a weight-based formula for estimation insertion length.A prospective was performed over 6-month period tertiary NICU. Infants...
Aims This study aims to determine if there is a difference in the pharyngeal pressure, measured as surrogate for continuous positive distending airway delivered premature infants between two commonly used heated, humidified high‐flow nasal cannulae ( HHHFNC ) devices: F isher & P aykel H ealthcare and V apotherm 2000i. Methods Pharyngeal pressure measurements were taken from stable receiving respiratory support. Flow rates of 2–8 L/min studied. Results Nine had recorded with both devices...
To determine the range of cerebral blood flow velocities (CBFVs) and Doppler indices cerebrovascular resistance in normal-term neonates as a baseline for study hypoxic-ischaemic encephalopathy.The CBFVs, resistive index (RI) pulsatility (PI) were measured anterior middle arteries (ACA MCA) 38 normal neonates.The mean peak systolic, end diastolic time-averaged (PSV, EDV TAV) 36.3 ± 6.6, 12.4 3.9 22.0 4.0 cm/s (ACA) 41.4 13.2, 13.0 5.5 25.8 7.9 (MCA), respectively. All CBFVs ACA correlated...
Background: Gastric tubes are used in nurseries on a daily basis. Various methods of estimating gastric tube length for insertion using anatomical landmarks to assist correct placement. Sometimes, however, they can be up 55% inaccurate. In 2012, we published weight-based formula estimate insertion. Purpose: This study reviews the rates placement, as confirmed by radiography, after incorporation this into bedside practice. Methods: A 6-month prospective was performed tertiary neonatal...
To determine the impact of a multidisciplinary fetal surveillance education program (FSEP) on term neonatal outcomes.A retrospective cohort study outcomes before (1998-2004) and after (2005-2010) introduction FSEP. Clinical data was collected for all infants admitted to intensive care unit (NICU) in Australia between 1998 2010. Infants with congenital abnormalities were excluded. Neonatal mortality severe morbidity (admission NICU, respiratory support, hypoxic encephalopathy) compared FSEP...
Background Care for infants born at 22–24 weeks’ gestation varies globally, with an increasing willingness to provide survival-focused (‘active’) care 22 in recent years. This study aims report changes weeks before and after the introduction of a statewide guideline extreme prematurity (EP). Methods A retrospective cohort was conducted, including all live births tertiary perinatal centres from 1 January 2015 31 December 2022 Victoria, Australia. Medical records were reviewed obtain antenatal...
Background Fetal growth restriction (FGR) is an important reason for premature delivery and a leading cause of perinatal morbidity mortality. We aimed to evaluate whether classification as small gestational age (SGA; <10th centile) at birth or antenatal suspicion FGR was more strongly associated with neonatal mortality in preterm infants.
Background: Caesarean birth, without prior labour, is associated with an increased risk of neonatal respiratory morbidity among term infants. The concentration lamellar bodies in amniotic fluid reflects pulmonary surfactant production and release, thus used preterm populations as a marker fetal lung maturity. Whether body (AFLBC) may correlate factors for distress has not previously been evaluated. Aims: To determine the relationship between AFLBC following caesarean birth. Methods: 249...
<h3>Background</h3> NCPAP facilitates successful extubation. It is unclear whether HFNC are as effective in preventing extubation failure. In addition to an alternative modality of respiratory support may result less nasal trauma than NCPAP. <h3>Methods</h3> 132 preterm ventilated infants were randomised and stratified by gestation(< 28 vs 28–32 weeks). Primary outcome was failure defined a composite 3 pre-specified criteria the 7 days post-extubation. Individual not mutually exclusive...
Background Echocardiography is an important technique in neonatal care. The heart of a premature baby known to be different from that term baby, and there paucity literature regarding reference cardiac measurements for this population, especially the very low birth weight (VLBW) infants. Objective We aimed present values echocardiography VLBW preterm Study Design This was retrospective observational study taking place over 11-year period. collected data reports echocardiographic examinations...
High-flow nasal cannulae (HFNC) wird zunehmend als Alternative zur CPAP-Atemhilfe bei Frühgeborenen eingesetzt. Zahlreiche Studien wurden in den vergangenen Jahren dazu publiziert. Flows von 1–8l/min gewärmter und angefeuchteter Luft finden derzeit Verwendung. Häufige Indikationen sind Apnoe-Bradykardie-Syndrom Atemnotsyndrom. Wir berichten über unsere Erfahrungen mit HFNC Frühgeborenen. Resultate einer abgeschlossenen Studie (Wilkinson DJ et al, J Perinatol 2008; 28:42–47) zu pharyngealen...