A5050884288- Machine Fault Diagnosis Techniques
- Engineering Diagnostics and Reliability
- Peripheral Neuropathies and Disorders
- Tissue Engineering and Regenerative Medicine
- Myasthenia Gravis and Thymoma
- Autoimmune Neurological Disorders and Treatments
- Industrial Technology and Control Systems
- Genetic Neurodegenerative Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Systemic Lupus Erythematosus Research
- Multilevel Inverters and Converters
- Complement system in diseases
- Sensorless Control of Electric Motors
- Diabetes Treatment and Management
- Hereditary Neurological Disorders
- Advanced X-ray Imaging Techniques
- Mesenchymal stem cell research
- Ion channel regulation and function
- Blood Pressure and Hypertension Studies
- Molecular Sensors and Ion Detection
- Calpain Protease Function and Regulation
- Physiological and biochemical adaptations
- Electrospun Nanofibers in Biomedical Applications
- Sulfur Compounds in Biology
- Brain Metastases and Treatment
Southeast University
2024-2025
Zhongda Hospital Southeast University
2022-2023
Chinese PLA General Hospital
2010-2022
Ningbo University
2015
Harbin Medical University
2014
Second Affiliated Hospital of Harbin Medical University
2014
Background Although hemoglobin A1c (HbA1c) is closely related to diabetes, its relationship with the incidence of hypertension still unknown, so we aimed evaluate between HbA1c and in general population. Method In this large prospective cohort study a median follow-up 2 years, included 4,074 participants from China Health Nutrition Survey (CHNS). Multivariate COX regression, subgroup analysis, receiver operator characteristic (ROC) curve restricted cubic spline (RCS) were used incidental...
Abstract Stem cell transplantation is a promising therapeutic strategy for myocardial infarction. However, transplanted cells face low survival rates due to oxidative stress and the inflammatory microenvironment in ischemic heart tissue. Melatonin has been used as powerful endogenous antioxidant protect from injury. melatonin cannot play long-lasting effect against hostile microenvironment. Nano drug delivery carriers have ability loaded degradation physiological environments controlled...
Myocardial infarction (MI), one type of ischemic heart disease, is a major cause disability and mortality worldwide. Currently, extracellular vesicles (EVs) derived from adipose-derived stem cells (ADSC) have been proven to be potentially promising therapeutic treatment for MI. However, the inconvenience isolation, low productivity, high cost EVs greatly limits their application in clinic. In this study, we constructed novel biomimetic ADSC-derived nanovesicles (ADSC NVs) achieve cell-free...
The clinical characteristics of POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes) syndrome in China are largely unknown. This work thus studied the manifestations China.We retrospectively reviewed medical records 82 patients with our hospital made a comparison those reported outside China.There were patients. Forty (49%) 45 years old or younger. Sensorimotor deficits common initial symptoms. as follows: (i) peripheral neuropathy abnormal electromyogram seen all...
The proliferation of vascular smooth muscle cells (VSMCs) is one the key events during progress atherosclerosis. activated liver X receptor (LXR) signalling pathway demonstrated to inhibit platelet-derived growth factor BB (PDGF-BB)-induced VSMC proliferation. Notably, following PDGF-BB stimulation, expression intercellular adhesion molecule-1 (ICAM-1) by VSMCs increases significantly. In this study, anti-ICAM-1 antibody-conjugated liposomes were fabricated for targeted delivery a...
Atherosclerosis is the leading cause of vascular pathologies and acute cardiovascular events worldwide. Early theranostics atherosclerotic plaque formation critical for prevention associated complications. Osteopontin (OPN) expression in smooth muscle cells (VSMCs) has been reported as a promising molecular target diagnosis treatment plaques. The PPARδ agonist GW1516 shown to inhibit VSMC migration apoptosis. However, low aqueous solubility poor oral bioavailability, which are major...
An ac-fed PMSM drive system with reduced dc-link capacitance easily suffers from fluctuations of voltage which may aggravate modulation error and severe current ripple at low frequency. The occurrence impact the are discussed firstly. Then, a suppression method is proposed by adoption improved strategy where digital delay compensated enhanced observer (EVO). EVO predicts two-switching-period ahead to eliminate in measured voltage. accuracy design analyzed. index updated based on predicted...
Hashimoto's encephalopathy (HE) is an acute associated with thyroiditis. The majority of reported cases have been hypothyroidism, while hyperthyroidism are rare. current study on a 56-year old female patient HE, who was found to progressively aggregated dysarthria, gait disturbance, somniloquy and delirium. Thyroid function tests revealed that the had hyperthyroidism, high levels anti-thyroid antibodies. Following treatment corticosteroids, neurological/psychiatric symptoms were relieved...
To select optimal cut-off values of tumor markers in cerebrospinal fluid for the diagnosis meningeal carcinomatosis, concentrations CEA, CA125, CA153, CA199, CA724, CYFRA21-1, AFP and NSE were determined by means double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) 21 MC patients, 25 cancer patients without leptomeningeal disease (group one) 45 meningitis two) using Roche E170 modular immunoassay analyzer. Optimal selected based on a receiver-operating characteristic curve. The...
A 27-year-old woman presented with a 1-year history of progressive weakness and grip myotonia in both hands. There was no family any similar condition personal cataracts. Physical examination revealed the muscles face, neck, shoulder girdle, Myotonia elicited percussion tongue (see video), finger extensors, thenar eminence. Sensation, coordination, cognition were normal. Electromyography showed myotonic discharges low-amplitude motor-unit potentials short duration, indicating myopathy. Serum...
Objectives. Studies have shown that fasting blood glucose (FBG) is closely associated with poor prognosis in patients coronary heart disease (CHD) after percutaneous intervention (PCI), but its association in-stent restenosis (ISR) still unclear. Therefore, this study was to explore the between FBG ISR CHD PCI. Design. In cohort study, we included 531 who underwent Logistic regression, receiver operating characteristic (ROC), subgroup analysis and restricted cubic spline (RCS) were used...
In order to study the influence of freezing and thawing on dynamic behavior ceramsite concrete, specimens with four kinds volume fraction including 0%, 15%, 30% 45% which subjected 0, 10, 20, 30 40 cycles respectively, are tested by means Spilt Hopkinson Pressure Bar technique. The experimental results showed that under loading ceramisite concrete was weakened increasing number freeze-thaw cycles. Changes compressive strength damage evolution affected cycling discussed in paper.
Cardiovascular diseases are closely related to structural blood capillaries lesions.Herein, microscopic investigations of mouse were performed at multiple spatial resolution by using synchrotron X-ray in-line phase contrast tomography and scanning transmission microscopy (STXM).The chemically fixed without any agents selected.For the first time, a periodic bamboo-shaped structure was observed nanoscale STXM, three-dimensional tomographic slices sub-micrometer further confirmed wave profile...