A5034197167- Cerebrovascular and Carotid Artery Diseases
- Dementia and Cognitive Impairment Research
- Cardiovascular Health and Disease Prevention
- Advanced Neuroimaging Techniques and Applications
- Neurological Disease Mechanisms and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Acute Ischemic Stroke Management
- Advanced MRI Techniques and Applications
- Microbial Community Ecology and Physiology
- Motor Control and Adaptation
- Functional Brain Connectivity Studies
- Stroke Rehabilitation and Recovery
- Optical Imaging and Spectroscopy Techniques
- Facility Location and Emergency Management
- Autism Spectrum Disorder Research
- Mental Health via Writing
- Lung Cancer Diagnosis and Treatment
- Atomic and Subatomic Physics Research
- Visual perception and processing mechanisms
- Spatial Neglect and Hemispheric Dysfunction
- Digital Mental Health Interventions
- Cerebrovascular and genetic disorders
- Algal biology and biofuel production
- Urban Transport and Accessibility
- Thermodynamic properties of mixtures
Renji Hospital
2010-2022
Shanghai Jiao Tong University
2010-2022
Sabre (United States)
2015
Neurology, Inc
2010
University of Science and Technology Beijing
2009
In this cross-sectional study, we aimed to explore the mechanisms of early cognitive impairment in a post stroke non-dementia cerebral small vessel disease (SVD) cohort by comparing SVD score with structural brain network measures. 127 patients were recruited consecutively from clinic, comprising 76 individuals mild (MCI) and 51 no (NCI). Detailed neuropsychological assessments multimodal MRI performed. scores calculated on standard scale, measures analyzed diffusion tensor imaging (DTI)....
Background Social media listening is a new approach for gathering insights from social platforms about users’ experiences. This has not been applied to analyse discussions Alzheimer’s disease (AD) in China. Aims We aimed leverage multisource Chinese data gain deeper into the current state of daily management patients with AD and burdens faced by their caregivers. Methods searched nine mainstream public online China September 2010 March 2024. Natural language processing tools were used...
Abnormal reductions in cortical cerebral blood flow (CBF) have been identified subcortical vascular cognitive impairment (SVCI). However, little is known about the pattern of CBF reduction relation with degree impairment. measured 3D Arterial Spin Labeling (ASL) perfusion MRI helps detect functional changes subjects SVCI. We aimed to compare maps ischemic disease (SIVD) and without relationship regions brain according z-score. A total 53 SVCI 23 matched SIVD (controls) underwent a...
<i>Background/Aims:</i> To investigate whether diffusion tensor imaging (DTI) is more sensitive than conventional MRI at detecting cognitive deterioration in patients with subcortical ischemic vascular disease (SIVD). <i>Methods:</i> Forty-two SIVD had a diagnosis of no impairment (NCI), impairment/no dementia or (VaD). Whole-brain DTI histography and routine were performed on these participants. <i>Results:</i> There significant differences between...
<b><i>Background and Purpose:</i></b> To assess the validity of Montreal Cognitive Assessment (MoCA) Mini-Mental State Examination (MMSE) in detection vascular mild cognitive impairment (VaMCI) patients with subcortical ischemic disease (SIVD). <b><i>Methods:</i></b> Among 102 SIVD patients, both cutoff scores MMSE MoCA for differentiating VaMCI from no (NCI) or dementia (VaD) were determined by receiver operator characteristic (ROC) analysis....
The presence and pattern of iron accumulation in subcortical vascular mild cognitive impairment (svMCI) their effects on cognition have rarely been investigated. We aimed to examine brain deposition svMCI subjects using quantitative susceptibility mapping (QSM). Moreover, we investigate the correlation between severity as indicated by z-scores. recruited 20 ischemic disease (SIVD) patients who fulfilled criteria for svMCI. control group comprised 19 SIVD without impairment. groups were...
Recent neuroimaging studies have shown that people with subcortical vascular cognitive impairment (sVCI) structural and functional abnormalities in the frontal lobe brain sites. In this study, we used seed-based resting-state connectivity (rsFC) analysis voxel-mirrored homotopic (VMHC) techniques to investigate alteration of rsFC patients sVCI. magnetic resonance images were acquired for 51 cerebrovascular disease. All subdivided based on status into 29 sVCI 22 controls; patient...
We conducted a cross-sectional study to characterize the relationship between total and modified small vessel disease (SVD) score with vascular cognitive impairment (VCI). Patients (n = 157) ages of 50 85 years old who had suffered their first lacunar infarction were analyzed prospectively. Brain magnetic resonance imaging was performed identify SVD manifestations, which used calculate or scores. Neuropsychological assessments measured function. Spearman correlation analysis demonstrated...
Objectives: We aim to investigate whether multi-dimensional diffusion tensor imaging (DTI) measures can sensitively identify different cognitive status of cerebral small vessel disease (CSVD) and explore the underlying pattern white matter disruption in CSVD. Methods: Two hundred two participants were recruited, composed 99 CSVD patients with mild impairment (VaMCI) 60 no (NCI) 43 healthy subjects as normal controls (NC). Full domain neuropsychological tests diffusion-weighted performed on...
Densities and viscosities have been measured as a function of composition for the binary liquid mixture diethylene glycol monobutyl ether CH3(CH2)3O(CH2)2O(CH2)2OH + water in temperature range from (293.15 to 333.15) K at atmospheric pressure. were determined using capillary pycnometer. Viscosities with Ubbelohde viscometer. From experimental data, excess molar volumes VE viscosity deviations δη calculated. This system shows negative ideal behavior. Excess correlated by Redlich−Kister type...
ABSTRACT Background: Cerebral small vessel disease (SVD) is the common cause of cognitive decline in old population. MRI can be used to clarify its mechanisms. However, surrogate markers for early impairment SVD remain uncertain date. We investigated impacts cerebral microbleeds (CMBs), diffusion tensor imaging (DTI), and brain volumetric measurements a cohort post-stroke non-dementia patients. Methods: Fifty five patients were consecutively recruited categorized into two groups as no (NCI)...
To investigate the disruption of white matter (WM) integrity in patients with subcortical vascular cognitive impairment (SVCI) multimodal structural magnetic resonance imaging (MRI), and to explore relationships between WM damage, network disruptions, general function decline.Twenty-eight SVCI twenty control subjects underwent MRI scans neuropsychological assessment. volume (WMV), hyperintensities (WMH), lacunar infarcts (LI), diffusion tensor parameters characteristics were compared two...
Mild cognitive impairment is an early stage of Alzheimer's disease. Increasing evidence has indicated that training could improve abilities MCI patients in multiple domains, making it a promising therapeutic approach for MCI. However, the effect long-time not been widely explored. It also necessary to evaluate extent how reduce convertion rate from AD. The SIMPLE study multicenter, randomized, single-blind prospective clinical trial assessing effects computerized on different domains...
As a common cause of vascular cognitive impairment (VCI), subcortical ischemic disease (SIVD) is defined primarily by lacunes and white matter lesions (WMLs) detected conventional neuroimaging techniques. Diffusion tensor imaging (DTI), which made possible the in vivo assessment (WM) integrity, offers powerful tool to study WMLs diseased brains. The objectives determine whether DTI more sensitive on detecting deterioration SIVD patients than MRI neuropsychological correlations these indices...
A new disposable percutaneous positioning device was developed which permits adjustment of the fixing puncture angle while performing a core needle lung biopsy (CNLB). The aim study to explore accuracy and clinical safety during CT-guided CNLB.A prospective, open randomized controlled with two parallel groups conducted on 150 patients pulmonary nodules between July 1, 2018 June 30, 2019 including 101 males 49 females who were divided (allocation ratio: 1:1) into standard CNLB group without...