Jun Fan

ORCID: 0009-0009-0713-5411
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About
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Research Areas
  • Ferroptosis and cancer prognosis
  • Pituitary Gland Disorders and Treatments
  • Cancer Immunotherapy and Biomarkers
  • Oral and Maxillofacial Pathology
  • Acute Myocardial Infarction Research
  • Meningioma and schwannoma management
  • Vascular Tumors and Angiosarcomas
  • Periodontal Regeneration and Treatments
  • Ear and Head Tumors
  • Cancer-related molecular mechanisms research
  • Diabetic Foot Ulcer Assessment and Management
  • RNA modifications and cancer
  • Testicular diseases and treatments
  • Signaling Pathways in Disease
  • Bone Tumor Diagnosis and Treatments
  • Intracranial Aneurysms: Treatment and Complications
  • Orthopedic Surgery and Rehabilitation
  • Adipose Tissue and Metabolism
  • Glioma Diagnosis and Treatment
  • Reconstructive Surgery and Microvascular Techniques
  • Cancer Genomics and Diagnostics
  • Foot and Ankle Surgery
  • Immune cells in cancer

Nanjing Medical University
2024-2025

Jiangsu Province Hospital
2024-2025

First People's Hospital of Chongqing
2017

Air Force Medical University
2013

Xijing Hospital
2013

Abstract We employed single‐cell analysis techniques, specifically the inferCNV method, to dissect complex progression of lung adenocarcinoma (LUAD) from in situ (AIS) through minimally invasive (MIA) (IAC). This approach enabled identification Cluster 6, which was significantly associated with LUAD progression. Our comprehensive included intercellular interaction, transcription factor regulatory networks, trajectory analysis, and gene set variation (GSVA), leading development signature...

10.1111/jcmm.18408 article EN cc-by Journal of Cellular and Molecular Medicine 2024-06-01

Autologous platelet-rich plasma (PRP) has been extensively investigated for large bone defect treatment, but its clinical application is harassed by controversial outcome, due to highly variable PRP quality among patients. Alternatively, allogeneic from well-characterized donors cannot only generate more consistent and reliable therapeutic effect also avoid harvesting quantities of blood, an additional health burdens However, the use treatment generally less investigated, especially...

10.3727/096368912x653183 article EN Cell Transplantation 2013-01-01

ABSTRACT Immune checkpoint inhibitors (ICIs) represent a groundbreaking advancement in cancer therapy, substantially improving patient survival rates. Our comprehensive research reveals significant positive correlation between coagulation scores and immune‐related gene expression across 30 diverse types. Notably, tumours exhibiting high demonstrated enhanced infiltration of cytotoxic immune cells, including CD8 + T natural killer (NK) macrophages. Leveraging the TCGA pan‐cancer database, we...

10.1111/jcmm.70525 article EN cc-by Journal of Cellular and Molecular Medicine 2025-03-30

Epithelioid angiomyolipoma (EAML) is a tumor with malignant potential, as evidenced by its pathological features. Further investigation into additional characteristics, particularly in imaging, of great significance for non-invasive detection methods to understand potential. In this context, we present case study 47-year-old male patient right renal EAML. The underwent nephrectomy but subsequently developed liver metastasis. Next-generation sequencing confirmed mutations tuberous sclerosis 2...

10.3389/fonc.2025.1555092 article EN cc-by Frontiers in Oncology 2025-04-16

Lung adenocarcinoma (LUAD) is a tumour characterized by high heterogeneity. Although there are numerous prognostic and immunotherapeutic options available for LUAD, dearth of precise, individualized treatment plans. We integrated mRNA, lncRNA, microRNA, methylation mutation data from the TCGA database LUAD. Utilizing ten clustering algorithms, we identified stable multi-omics consensus clusters (MOCs). These were then amalgamated with machine learning approaches to develop robust model...

10.1111/jcmm.18520 article EN cc-by Journal of Cellular and Molecular Medicine 2024-07-01

Acute Coronary Syndrome (ACS) continues to be a leading cause of death and illness worldwide. Differentiating stable from unstable coronary plaques is essential for enhancing patient outcomes. This research investigates the role CD147 as biomarker plaque stability among artery disease patients.

10.3389/fcvm.2024.1425817 article EN cc-by Frontiers in Cardiovascular Medicine 2024-09-13

患者女,35岁.发现右额部包块3年就诊,于2009年2月14日入院.无头痛、头昏,无恶心、呕吐,无发热及四肢抽搐,神志清楚,一般情况尚可.体检:右额部隆起肿块直径约3.0 cm,CT检查提示右侧额骨膨胀性缺损,其内见菊花放射状骨小梁,内板不连续,考虑肉芽肿或血管瘤。

10.3760/cma.j.issn.0529-5807.2010.02.013 article ZH-CN 2010-02-01

Objective To investigate the effects of open reduction and internal fixation plus calcium sulfate artificial bone graft for treatment Sanders type III IV calcaneal fractures. Methods The clinical data patients with fractures treated from January 2012 to December 2015 were retrospectively reviewed by case-control study. The divided into two groups as group (open combined graft) control fixation). was composed 17 cases, among which there 12 males five females age range 19-62 years...

10.3760/cma.j.issn.1001-8050.2017.11.013 article EN 2017-11-15

Objective To explore the relationship between craniopharyngioma based on QST classification with invovlement of third ventricle floor and meninges its clinical significance. Methods The data 17 primary patients involvement (6 cases Q type, 3 S type 8 T type) undergoing total tumor resection under neuroendoscopy from January 2018 to October 2019 at Neurosurgery Department Nanfang Hospital, Southern Medical University were retrospectively analyzed. Tumor tissue samples taken all during...

10.3760/cma.j.cn112050-20191125-00497 article EN Zhonghua shenjing waike zazhi 2020-03-28
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