A5034997391- Colorectal and Anal Carcinomas
- MRI in cancer diagnosis
- Colorectal Cancer Surgical Treatments
- Prostate Cancer Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Prostate Cancer Treatment and Research
- Sarcoma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Nonmelanoma Skin Cancer Studies
- Spine and Intervertebral Disc Pathology
- Elbow and Forearm Trauma Treatment
- Colorectal Cancer Screening and Detection
- Lymphoma Diagnosis and Treatment
- Cancer and Skin Lesions
- Lanthanide and Transition Metal Complexes
- Shoulder Injury and Treatment
- Testicular diseases and treatments
- Aortic Disease and Treatment Approaches
- Neuroblastoma Research and Treatments
- Management of metastatic bone disease
- Fungal Infections and Studies
- Cardiac tumors and thrombi
- Urologic and reproductive health conditions
- Vascular Tumors and Angiosarcomas
- Cardiovascular and Diving-Related Complications
Krankenhaus Dresden-Friedrichstadt
2009-2024
Städtisches Klinikum Dresden
2008-2024
TU Dresden
2003-2021
University Hospital Regensburg
2011
Klinik und Poliklinik für Psychotherapie und Psychosomatik
1995-2008
University Hospital Carl Gustav Carus
1996-2007
Total neoadjuvant therapy has been increasingly adopted for multimodal rectal cancer treatment. The optimal sequence of chemoradiotherapy (CRT) and chemotherapy needs to be established. To report the long-term results secondary end points prespecified in Randomized Phase 2 Trial Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Neoadjuvant Therapy (CAO/ARO/AIO-12 trial) Locally Advanced Rectal Cancer. This analysis a randomized clinical trial included 311 patients who were...
The prognostic value of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in the assessment post-treatment residual masses patients with Hodgkin's disease (HD) or non-Hodgkin's lymphomas (NHL) was evaluated. We prospectively studied 58 HD (n = 43) NHL 15) who had post-therapeutic complete remission (CRu) indicated by computerized tomography. Analysis 62 locations FDG-PET performed separately for and NHL. Patients a PET-positive mass [standardized uptake (SUV) > 3] recurrence...
Abstract Purpose: To compare enhancement of liver parenchyma in MR imaging after injection hepatocyte‐specific contrast media. Materials and Methods: Patients (n = 295) with known/suspected focal lesions randomly received 0.025 mmol gadoxetic acid/kg body weight or 0.05 gadobenate dimeglumine/kg by means bolus injection. was performed before immediately injection, the delayed phase at approved time points (20 min acid 40 dimeglumine). The relative for overall population a cirrhotic subgroup...
Synchronous metastases are considered a negative prognostic factor in patients with metastatic colorectal cancer (CRC). We investigated the outcomes of stage IV CRC undergoing complete gross resection (R0/1) both primary tumor and under guidance multidisciplinary team (MDT).All synchronous were retrieved from prospective database. Patients treated 2006 to 2017 who underwent analyzed. Various factors, including multiple sites complex procedures, investigated. Univariate multivariate overall...
The purpose of this phase III clinical trial was to compare two different extracellular contrast agents, 1.0 M gadobutrol and 0.5 gadopentate dimeglumine, for magnetic resonance imaging (MRI) in patients with known or suspected focal renal lesions. Using a multicenter, single-blind, interindividual, randomized study design, both agents were compared total 471 regarding their diagnostic accuracy, sensitivity, specificity correctly classify lesions the kidney. To test noninferiority accuracy...
Abstract Background Mesenchymal neoplasms (sarcomas) of skin are rare. Patients with sarcomas were analyzed over the last decade. Methods Over a 10‐year period, we conducted retrospective analysis patients diagnosed and treated in an urban academic teaching hospital Saxony, Germany. Clinical pathologic files used. Results We identified 65 adult 67 primary cutaneous sarcomas. The mean age was 73.1 (±15.5) years male predominance (78.5%). None detected by cancer screening program. diagnosis...
Objective: Magnetic resonance imaging–based subdivision of the pelvis into 7 compartments has been proposed for pelvic exenteration. The aim present anatomical study was to describe topographic anatomy these and define relevant landmarks surgical dissection planes. Background: Pelvic as it relates exenterative surgery is complex. Demonstration peculiarities based on operative situs hindered by inaccessibility small tumor bulk itself. Materials Methods: Thirteen formalin-fixed specimens were...
Dystrophic calcification (DC) is a risk factor for conservative treatment failure in chronic leg ulcers of various pathologies.We performed retrospective noncontrolled trial 212 patients with 362 who underwent ulcer shave excision subsequent skin grafting. The existed at least 3 months, and no healing was achieved good care. Tissue subjected to histopathology (hematoxylin-eosin van Kossa stains).DC evident 39 (18%). Metaplastic subcutaneous bone formation observed 15 (7%). Clinical symptoms...
Abstract Purpose: To evaluate the efficacy and safety of 0.1 mmol/kg gadodiamide administration for contrast‐enhanced magnetic resonance angiography (MRA) in detecting hemodynamically relevant renal artery stenosis (RAS) when compared with intraarterial digital subtraction (IA‐DSA) as gold standard. Materials Methods: In a multicenter, controlled study, 395 patients suspected or known RAS were included. Three independent readers evaluated MRA images. Two IA‐DSA images subsequently achieved...
Rectal cancer invading adjacent organs (T4) and locally recurrent rectal (LRRC) pose a special challenge for surgical resection. We investigate the diagnostic performance of MRI results that can be achieved with MRI-guided surgery. All consecutive patients who underwent MRI-based multivisceral resection T4 adenocarcinoma or LRRC between 2005 2019 were included. Pelvic findings reviewed according to seven-compartment staging system correlated histopathology. Outcomes investigated by comparing...
Abstract Purpose Sidedness has emerged as a prognostic factor for metastatic colorectal cancer treated with modern systemic therapies. This study investigates whether it is also relevant an unselected patient cohort including all stages. Methods All consecutive patients admitted colon between 1995 and 2018 were retrieved from institution-held database. Patients divided into two cohorts. The first included without distant metastases who able to undergo curative resection. second presented...
Transesophageal echocardiography (TEE) revealed a 3‐mm‐large patent foramen ovale (PFO). No other reason for these neurological events could be found and the patient underwent percutaneous closure of PFO with CARDIA ® Star 03/30 device without periprocedural complications. Four weeks later, routine control any adverse clinical symptoms. Surprisingly, perforation aortic root by an umbrella strut small shunt from to right atrium. Magnetic resonance imaging (MRI) confirmed diagnosis...
High-risk basal cell carcinoma (BCC) is an aggressive malignant tumor of the skin, with a potential perineural, lymphatic and vascular spreading. This review presents most common types anatomical sites high-risk BCC, evaluates diagnosis, clinical presentation treatment options available. Based on current data, micrographically controlled (Mohs) surgery or frozen section excision choice. In cases impossible complete resection, radiotherapy alternative. patients high risk recurrence, adjuvant...
Resection of the internal jugular vein can be necessary in cases radical neck dissection or even involving benign neoplasms such as glomus tumors. According to triad described by Virchow (ie, stasis blood flow, damage endothelium, and changes hemostasis), development a thrombosis venous vessels superior resected seems possible. The aim this study was determine extension possible intracranial after wound healing.A total 17 patients requiring resection were evaluated prospectively using...
In several mammals, a direct connection between the nasal cavity and oral is common finding. The structure named nasopalatine duct (NPD). It has been hypothesized to be functional in terms of transportation odorants from cavity. humans, NPD exists during embryological development. infundibulum incisive fossa typically closed at time birth. We present case 24-year-old man who presented with persistent NPD. By means thin, soft tube, it was possible probe Magnetic resonance imaging revealed...
A 52-year-old woman with pulmonary sarcoidosis on immunosuppressive therapy developed infiltrates and cutaneous granulomatous abscesses after a trip to the USA in April 2005. hyphomycete was identified, further characterized by gene probe as Coccidioides spp. then definitively identified posadasii polymerase chain reaction sequencing. Antibodies towards were detected. The infection successfully treated posaconazole (Noxafil), 2 x 400 mg/d.