A5112128277- Organ Transplantation Techniques and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Transplantation: Methods and Outcomes
- Gallbladder and Bile Duct Disorders
- Intracerebral and Subarachnoid Hemorrhage Research
- Neonatal and fetal brain pathology
- Ocular Surface and Contact Lens
- Stroke Rehabilitation and Recovery
- Liver Disease and Transplantation
- Nasolacrimal Duct Obstruction Treatments
- Sinusitis and nasal conditions
- melanin and skin pigmentation
- Acute Ischemic Stroke Management
- Liver Disease Diagnosis and Treatment
- Congenital Diaphragmatic Hernia Studies
- PI3K/AKT/mTOR signaling in cancer
- Hepatocellular Carcinoma Treatment and Prognosis
- Neonatal and Maternal Infections
- Forensic Entomology and Diptera Studies
- Skin Protection and Aging
- Monoclonal and Polyclonal Antibodies Research
- Pregnancy-related medical research
- Peroxisome Proliferator-Activated Receptors
- Extracellular vesicles in disease
- Neurological and metabolic disorders
Sichuan Mianyang 404 Hospital
2025
Zhejiang University
2013-2025
Beijing Chao-Yang Hospital
2021
Capital Medical University
2021
International Peace Maternity & Child Health Hospital
2021
Shanghai Jiao Tong University
2021
Children’s Hospital of Fudan University Xiamen Branch
2020
Children's Hospital of Philadelphia
2020
University of Pennsylvania
2020
Philadelphia University
2020
The present study was designed to explore the cross talk between fatty acid synthase (FASN) and HER2 (ErbB2) in ovarian cancer. A total of 60 cancer patients 15 normal tissues were enrolled. Tissue array conducted by using a tissue microarray instrument. Immunohistochemistry performed quantify expressions FASN. FASN detected be distributed cell cytoplasm significantly correlated with grade (p = 0.000) FIGO staging 0.000). Patients overexpression tend have worse overall survival rate also...
This study attempts to develop a novel apoptosis-related predictive model for cervical cancer. Differentially expressed genes were identified using TCGA, GEO, and MSigDB databases. A 13-gene prognostic was constructed multiple regression analyses. The low-risk group exhibited low tumor purity high ESTIMATE immune scores. Most of the checkpoints in at higher levels than those high-risk group. also had relatively more infiltrating cells. An independent pertaining cell apoptosis has been built...
With the increasing popularity of dogs as pets, cases hydrocephalus have risen significantly. Due to ongoing challenges in diagnosis and treatment hydrocephalus, advancements magnetic resonance imaging (MRI) technology greatly enhanced diagnostic capabilities small animal clinical practice. Assessing ventricular size is crucial for management other neurological disorders. However, methods quantifying evaluating severity requires further optimization. This study involved 137 17 normal dogs....
Purposes. In this study, we aimed to verify plasma fibroblast growth factor 21 (FGF21) elevation in newly diagnosed overweight patients with type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease (NAFLD) evaluate the effectiveness of liraglutide on reducing fat content serum levels those patients. Methods. A 12-week, single-center, prospective study was conducted. Twenty T2DM NAFLD were recruited. healthy age, sex, body mass index (BMI) matched subjects enrolled as control...
The authors declare that they have no competing interests.
Low-level laser is being evaluated for treating rheumatoid arthritis (RA). Recently, the linear polarized infrared light (Super Lizer, SL) irradiation may also be useful RA treatment. However, molecular mechanism underlying effectiveness of SL on unclear. It has been IL-20 involved in disease progression.To understand how action, we constructed experimental model vitro using human fibroblast-like synoviocyte (MH7A) and collagen induced (CIA) rat vivo. We examined effect gene expression MH7A...
Objective: The management of liver receivers requires intense immunosuppression to prevent graft rejection. Mycophenolate mofetil (MMF) is a common immunosuppressant but frequently suffer dose reduction for gastrointestinal adverse reactions (GI). Hence, the enteric-coated mycophenolate sodium (EC-MPS) introduced as substitute MMF reduce GI. study was designed investigate efficacy, safety and exposure equation EC-MPS in transplant patients China.Methods: Ninety-two who administered or...
ABSTRACT Background Cervical cancer is one of the most common malignancies among women. Vesicle‐mediated transport mechanisms significantly influence tumor cell behavior through intercellular material exchange. However, prognostic significance in CC patients remains underexplored. Research Design and Methods We identified differentially expressed vesicle‐mediated transport‐related genes from TCGA GeneCards datasets differential expression analysis. constructed a model using Cox regression...
FDG PET/CT was performed for staging in a 15-year-old adolescent girl with cholangiocarcinoma, which showed only mild activity the tumor but more impressive right femoral fibrous cortical defect without any other hypermetabolic lesions elsewhere. Pathological examination of resected cholangiocarcinoma revealed significant neuroendocrine differentiation, lead to subsequent Ga-DOTATATE study. Unexpectedly, same also had increased activity.
To investigate the risk factors associated with persistent thrombocytopenia after liver transplantation (LT), and to explore effective measures for prevention.One hundred twenty-eight adult patients, who received in our hospital between January 2009 June 2012 met inclusive criteria, were enrolled study. The clinical data retrospectively analyzed, including pre-LT spleen volume, main portal vein size, coronary platelet white blood cell levels, total bilirubin level model of end stage disease...
Abstract Background Periodontal diseases and poor oral hygiene are potentially associated with decreased female fecundability. Fecundability refers to the probability of conception during a given period measured in months or menstrual cycles. This study aims examine whether halitosis is fecundability large sample Chinese women who planned be pregnant. Methods In 2012, total 6319 couples came for preconception care eight districts Shanghai, China were followed by telephone contact. Three...
Objective To explore the effects of personal follow-up guidance based on case management functional outcome and treatment compliance elderly stroke patients, lay foundation (CM) work. Methods Totally 169 patients were randomly divided into experimental group(n=83)and control group (n=86). Patients in given routine guidance, while management. The activities daily living two groups evaluated by modified Barthel index (MBI) Rankin scale(MRS) at time joining group, 1 month, 3 months, 6...
Objective To evaluate the efficacy of combined hemodialysis-hemoperfusion therapy compared with conventional dialysis in preventing uremic encephalopathy. Methods 45 enrolled patients on maintenance hemodialysis were randomized to receive hemadialysis(control group,21 cases)or monthly sequential hemoperfusion (study group,24 cases). The duration was 2-3 hours and 4.5 for use hemodialysis. Blood flow rates maintained at 200-250 ml/min dialysate rate 500 ml/min. Anticoagulation performed...
Objective To analyze the clinical efficacy and its influencing factors of combined liver kidney transplantation (CLKTx).Method From February 1999 to April 2013,CLKTx was performed on 26 cases (CLKTx group),liver at same time 35 (liver group).The long-term survival,rejection complications were retrospectively analyzed.Result Fifteen recipients in CLKTx group survived with normal graft function,and 1-,2-and 5-year survival rate 88.9％,81.3％ 69.0％ respectively.The-,2-and 86.7％,82.1 ％ 65.2％...
Abstract Tumor microenvironment (TME) is often implicated in regulating the growth of tumors, but whether it can directly alter genetics tumors not known. Myeloma a plasma cell malignancy characterized by tumor cells bone marrow. Prior studies have shown that genomic instability and dendritic (DC) infiltration are common features human myeloma (MM). Mechanisms underlying MM largely unknown. Here we show interaction between DCs monocytes, leads to rapid induction mutator AID AID-dependent DNA...