A5100614945- MRI in cancer diagnosis
- Glioma Diagnosis and Treatment
- Advanced Neuroimaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Colorectal Cancer Surgical Treatments
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Liver Disease Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Bone and Joint Diseases
- Wound Healing and Treatments
- Medical Imaging and Pathology Studies
- Hepatitis B Virus Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Periodontal Regeneration and Treatments
- Fetal and Pediatric Neurological Disorders
- Anatomy and Medical Technology
- Cytokine Signaling Pathways and Interactions
- Osteoarthritis Treatment and Mechanisms
- Intracranial Aneurysms: Treatment and Complications
- Mesenchymal stem cell research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sepsis Diagnosis and Treatment
- Nerve injury and regeneration
- Radiation Dose and Imaging
Second Xiangya Hospital of Central South University
2012-2024
Central South University
2012-2024
First Affiliated Hospital of Xi'an Jiaotong University
2011-2024
Baoji City Central Hospital
2011-2024
Cardiovascular Institute Hospital
2024
Shanxi Medical University
2010-2023
First Hospital of Shanxi Medical University
2023
ORCID
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2021
Fourth Affiliated Hospital of China Medical University
2021
Abstract The purpose of this study was to permit bone marrow mesenchymal stem cells (BMSCs) reach their full potential in the treatment chronic wounds. A biocompatible multifunctional crosslinker based temperature sensitive hydrogel developed deliver BMSCs, which improve inflammation microenvironments detailed vitro investigation found that is suitable for BMSC encapsulation and can promote secretion TGF-β1 bFGF. In vivo , full-thickness skin defects were made on backs db/db mice mimic...
Nestin has been shown to be expressed in the hair follicle, both bulge area (BA) as well dermal papilla (DP). Nestin-expressing stem cells of BA and DP have previously pluripotent able form neurons other non-follicle cell types. The nestin-expressing from termed skin precursor or SKP cells. objective present study was determine major source follicle compare ability repair spinal cord injury. Transgenic mice which nestin promoter drives GFP (ND-GFP) were used order observe expression DP....
This study investigated the effects of multi-frequency mode ultrasound and vacuum technology on water loss (WL) garlic slices during osmotic dehydration (OD), their microstructure garlic. A new method OD for was proposed - Vacuum pretreatment coupled to assisted (VUOD). The results indicated that WL treated with VUOD (21.12%) significantly (p < 0.05) higher than normally (NOD) (10.67%), (VOD) (14.18%), (UOD) (11.20-13.56%). mass transfer mechanism proposed. Low-field nuclear magnetic...
Angiogenesis and re-epithelialization are critical factors in skin wound healing. Growth stem cells have demonstrated their active roles promoting these two processes. Peptides show similar effects with growth lower cost controllable properties. Here we report a biomimetic fragment of the laminin -Ser-Ile-Lys-Val-Ala-Val (SIKVAV)-conjugated chitosan hydrogel that can promote regeneration. In vitro found this peptide-conjugated significantly promoted BMSC adhesion proliferation. vivo,...
Skin wound healing is a complicated process that involves variety of cells and cytokines. Fibroblasts play an important role in this participate transformation into myofibroblasts, the synthesis extracellular matrix (ECM) fibers, secretion growth factors. This study assessed effects peptide Ser-Ile-Lys-Val-Ala-Val (SIKVAV)--modified chitosan hydrogels on skin healing. We investigated capability SIKVAV to promote cell proliferation migration, collagen, factors using fibroblasts vitro. also...
This study is to investigate the frequencies of T-helper (Th)22, Th17 and Th1 cells levels related cytokines in subchondral bone marrow patients with rheumatoid arthritis (RA). Bone peripheral blood samples were collected from RA, osteoarthritis (OA) healthy controls. The Th22, Th17, examined by flow cytometry. Levels interleukin (IL)-22, IL-17 IFN-γ ELISA. Disease Activity Score 28 joints (DAS28) RA analyzed. markedly increased comparing OA or Each T cell subset was elevated that patients....
The objective of the present study was to compare differentiation between breast cancer and benign lesions regional distribution characteristics in various subtypes using intravoxel incoherent motion (IVIM) parameters. This retrospective involved 119 patients with 22 lesions, who underwent 3.0T magnetic resonance imaging examinations. apparent diffusion coefficient (ADC) IVIM parameters (slow ADC, fast ADC fraction ADC) were obtained from diffusion-weighted (DWI) b-values 0, 50, 100, 150,...
To assess the value of combining susceptibility-weighted imaging (SWI) and dynamic susceptibility weighted contrast-enhanced (DSC) perfusion-weighted MRI (PWI) in assessing World Health Organization (WHO)grade for brain astrocytoma .A total 94 patients with pathologically confirmed astrocytomas underwent SWI DSC scans. The evaluation included intratumoral signal intensity (ITSS) relative cerebral blood volume (rCBV) max. receiver operating characteristic curve (ROC) was used to efficacy two...
Numerous attempts for detection of circulating tumor cells (CTC) have been made to develop reliable assays early diagnosis cancers. In this study, we validated the application folate receptor α (FRα) as marker detect CTC through tumor-specific ligand PCR (LT-PCR) and assessed its utility bladder transitional cell carcinoma (TCC). Immunohistochemistry FRα was performed on ten TCC tissues. Enzyme-linked immunosorbent assay (ELISA) both urine serum specimens from patients (n = 64 n 20,...
Patients with asthma COPD overlap syndrome (ACOS) are an important but poorly characterized group. This study sought to explore the distinct characteristics of ACOS on CT densitometry. The population was randomly selected from communities via questionnaires. All participants underwent low-dose volumetric chest both before and after bronchodilator administration. Each scan performed at full-inspiration full-expiration for Emphysema index (EI), air trapping (AT), mean lung density (MLD) total...
Ulcerative colitis is an inflammatory bowel disease with multiple pathogeneses. Here, we aimed to study the therapeutic role of ulinastatin (UTI), anti-inflammatory bioagent, and its associated mechanisms in treating colitis. Dextran sulfate sodium was administrated induce mice, a subgroup mice treated UTI. The gut barrier defect manifestations were determined via histological molecular experiments. In addition, transcriptomics, metagenomics, metabolomics employed explore possible underlying...
micro RNA s (mi s) function as oncogenes or tumor suppressors in human cancers by targeting mRNA for degradation and/or translational repression. miR‐497 has been proposed a suppressive mi and its deregulation is observed cancers. However, the prognostic value of underlying molecular pathways involved initiation development hepatocellular carcinoma ( HCC ) are poorly investigated. In present study, we found that mean level tissues was lower than adjacent nontumor tissues. Clinical data...
MicroRNAs (also referred to as miRNAs or miRs) play a crucial role in post-transcriptional gene regulation and serve negative regulators by controlling variety of target genes regulating diverse biological processes, such cell proliferation, invasion, migration apoptosis. Aberrant expression is associated with the development progression cancer. Recent studies have reported that may repress promote cancer-related via several different signaling pathways gallbladder cancer (GBC) patients...
BACKGROUND:We analyzed the factors related to AAD inform rational use of antibiotics in critically ill patients and reduce incidence by providing a reference for antibiotic clinical setting. MATERIAL AND METHODS:This study was retrospective analysis data who were hospitalized ICU First Teaching Hospital Xi'an Jiaotong University from January 1, 2015 December 31, 2016. Patients with assigned case group, all others control group. Basic collected selected patients. All relevant univariate or...