A5101905527- Animal Nutrition and Physiology
- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Rabbits: Nutrition, Reproduction, Health
- Advancements in Transdermal Drug Delivery
- Pharmaceutical studies and practices
- Insect and Pesticide Research
- Livestock and Poultry Management
- Coccidia and coccidiosis research
- Microscopic Colitis
- Pharmacological Effects of Natural Compounds
- Dermatology and Skin Diseases
- Polysaccharides Composition and Applications
- Crystallization and Solubility Studies
- Health Systems, Economic Evaluations, Quality of Life
- Respiratory viral infections research
- Congenital Diaphragmatic Hernia Studies
- Analytical Methods in Pharmaceuticals
- Clostridium difficile and Clostridium perfringens research
- Biosimilars and Bioanalytical Methods
- Medicinal Plant Research
- Fluid Dynamics and Mixing
- Ultrasound and Cavitation Phenomena
- Listeria monocytogenes in Food Safety
- Acne and Rosacea Treatments and Effects
Parul University
2023-2025
Odisha University of Agriculture and Technology
2024
Stempeutics (India)
2023
Valley Medical Center
2022
Sunshine Hospitals
2021
Gujarat Technological University
2021
Global University
2021
Indian Institute of Information Technology Vadodara
2016-2017
American Pharmacists Association
2017
University of Leicester
2015
Importance A safe and effective treatment for recurrent Clostridioides difficile infection (CDI) is urgently needed. Antibiotics kill toxin-producing bacteria but do not repair the disrupted microbiome, which promotes spore germination recurrence. Objectives To evaluate safety rate of CDI recurrence after administration investigational microbiome therapeutic SER-109 through 24 weeks. Design, Setting, Participants This phase 3, single-arm, open-label trial (ECOSPOR IV) was conducted at 72 US...
The objective of the present work was to develop and optimize an intranasal in situ gel Pramipexole dihydrochloride for enhanced drug delivery, better patient acceptability, possible proper treatment Parkinson’s disease. Preliminary studies were performed select formulation components identify key variables affecting formulation. optimization gelling system achieved by applying 32 full factorial design using Design-Expert® software (Stat-Ease 9.0.6 version) taking concentrations Poloxamer...
Four experiments with broilers and one laying hens were conducted to study the effects of processing hemicellulase supplementation guar meal (37.0% protein) on growth, feed efficiency, egg production. Guar at 0, 10, 15%, either in raw form or autoclaved 100, 102, 132 C for 3, 15, 30 min, was fed alone presence 0 250 ppm hemicellulase. In an experiment utilizing full-term broilers, 10 15% lincomycin (3.3 ppm) combination (25 ppm). The hen 36-week-old 8 weeks. They (102 C, 15 min) depressed...
The effects of gamma irradiation rye, corn, pectin, and guar gum supplementation procaine penicillin and/or pectic enzyme (Irgazyme-100) were studied. Addition 62.5% 4% or 2% in place corn significantly reduced chick growth (P < .05). Exposure to irradiation, penicillin, improved the chicks fed rye. Growth response on rye diet one more combinations was greater than that alone. Gamma supplementatin pectin almost eliminated their depressing properties. A combination failed give a further...
A two phase experiment was conducted with Leghorn pullets to study the effect of graded levels (0 18 μg/kg feed) vitamin D3, 25-OH-D3, l,25-(OH)2 -D3, and 1α-OH-D3 on production parameters hatchability eggs. Phase 1 21-week-old for a period 13 weeks. There were 10 treatments four replicates hens in each cage. Eggs incubated weekly 8 weeks beginning when 26 age. Another started first terminated all different fed same basal diet continuing 1100 ICU D3/kg feed 12 days daily changes recovery egg...
Donation after circulatory death (DCD) kidney transplants inevitably sustain a degree of warm ischaemic injury, which is manifested clinically as delayed graft function. The aim this study was to define the effects prolonged periods injury on renal function in normothermic haemoperfused model.Porcine kidneys were subjected 15, 60, 90 (n = 6 per group) and 120 min 4) situ ischaemia (WI) then retrieved, flushed with cold preservation fluid stored ice for 2 h. Kidneys underwent 3 h reperfusion...
Two experiments were conducted in litter floor pens with broiler-type chicks to determine the effect of amprolium-ethopabate, lasalocid, monensin, and lincomycin on growth, feed efficiency, feathering responses graded levels methionine. In Experiment 1, a pea-corn diet was supplemented 5 methionine (0 .3%) combination amprolium-ethopabate (125 140 ppm), lasalocid or monensin (121 ppm). second experiment, two different types diets (corn-soy pea-corn) used which differed primarily source...
The effects of feeding different levels protein and vitamin B12 on egg production hatchability eggs Single Comb White Leghorn hens were studied. Diets containing 16 32% corn-soybean meal with without 10 μg. per kg. diet employed. Egg fertility not significantly affected by level or supplement. However, increasing in the hen diets resulted a significant decrease hatchability. Vitamin supplementation both improved eggs. supplementary was adequate to support desirable when contained protein....
Two experiments were conducted with White Leghorn laying hens to study the effects of different cereal grains on production criteria and liver fat content. The results Experiment 1, in which pullets 21 weeks age used for a period 22 indicated that Gaines wheat or triticale (Trailblazer) equal corn supporting egg production, weight body weight, comparable feed consumption. Henry (a hard red winter class) was slightly, yet significantly (P < 0.05) inferior above criteria. No significant...
Application of Simplex Lattice Design in Formulation and Development Buoyant Matrices DipyridamoleMandlik Satish K, Adhikari Saugat, Deshpande Ameya A.
Abstract: Introduction: Microsponges provides a proficient drug delivery system for specific in the upper gastrointestinal tract with high loading capability. But formulation is affected by numerous process and design related factors. The intention of current research work was to formulate optimize floating gastroretentive microsponges glipizide, an antidiabetic drug, minimum number experiments, applying appropriate experimental design. Methods: decisive factors affecting were screened...
Recurrent Clostridioides difficile infection (rCDI) often occurs after standard-of-care antibiotics. VOWST oral spores (VOS, previously SER-109), an FDA-approved orally administered microbiome therapeutic, is indicated to prevent rCDI following antibiotics for rCDI.
One laying hen and three chick experiments were conducted to study the effect of cereal grains, citrus pectin, guar gum on liver fat chicks hens serum cholesterol chicks. Feeding wheat, rye, or 2% pectin in place corn reduced content. The decrease fed wheat rye was larger than that those (P less .05). smallest amount found livers diet. Wheat did not affect egg production weight, but caused a significant decline comparison with other treatments. Addition 4% control diet lowered fat, .05),...
The aim of the present study was to prepare floating matrix tablet glipizide by applying Simplex lattice design using kappa carrageenan, Hydroxypropylmethylcellulose K15M and sodium bicarbonate as independent variable. similarity factor (f2), time release 50 % drug 90 were taken dependent factors. A total 14 batches prepared given Design-Expert® Software (version- 9.0.6, Stat-Ease) response obtained for variables statistically evaluated. Radiological performed on healthy albino rabbits...
Lercanidipine Hydrochloride (LER) is widely used antihypertensive drug belonging to BCS Class II and showing pH dependent solubility. The bioavailability of LER limited because its poor water Inclusion complexes were prepared with β-Cyclodextrin (βCD) using kneading freeze drying techniques in different molar ratios enhance solubility improve dissolution characteristic the same. phase study was performed interaction between βCD solution. Phase graph showed a linear diagram classified as AL...
Objective: It is always challenging to prepare the floating gastro retentive formulation of high dose drug. The present research was aimed controlled release, matrix tablets metformin, using combination different ionic, anionic and polyanionic polymers with HPMC.Methods: Formulations were prepared sodium alginate, pullulan, kappa carrageenan, xanthan gum, poloxamer 68 in HPMC K15M. All by direct compression method evaluated for swelling, adhesive period drug release.Results: showed...