Kazutoshi Sugiyama
A5076373769- Diabetes Management and Research
- Pancreatic function and diabetes
- Diabetes and associated disorders
- Cardiac Arrhythmias and Treatments
- Lipoproteins and Cardiovascular Health
- Diabetes Treatment and Management
- Atrial Fibrillation Management and Outcomes
- Animal Genetics and Reproduction
- Heart Rate Variability and Autonomic Control
- Computational Drug Discovery Methods
- Meningioma and schwannoma management
- Cardiovascular Health and Disease Prevention
- Spinal Fractures and Fixation Techniques
- Neurological and metabolic disorders
- Cardiac electrophysiology and arrhythmias
- Birth, Development, and Health
- Non-Invasive Vital Sign Monitoring
- Thyroid Disorders and Treatments
- Acute Myocardial Infarction Research
- Neuroendocrine Tumor Research Advances
- Cardiovascular Syncope and Autonomic Disorders
- Neurofibromatosis and Schwannoma Cases
- Cancer, Lipids, and Metabolism
- Gestational Diabetes Research and Management
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Keio University
2018-2023
University of Toyama
2016-2020
Ashikaga Red Cross Hospital
2013-2015
To clarify the influence of hypertension and blood pressure (BP) control on thromboembolism major hemorrhage in patients with nonvalvular atrial fibrillation, a post hoc analysis J-RHYTHM Registry was performed.A consecutive series outpatients fibrillation enrolled from 158 institutions. Of 7937 patients, 7406 (70.8% men, 69.8±10.0 years) were followed for 2 years or until an event occurred. Hypertension defined as systolic BP ≥140 mm Hg, diastolic ≥90 history hypertension, and/or...
Coronary artery ectasia (CAE) is defined as a coronary dilatation with diameter ≥1.5 times greater than that of normal adjacent artery. All 3 vessels can be affected by CAE, but the incidence multivessel CAE among patients undergoing angiography quite low. We herein report an extremely rare case acute myocardial infarction due to massive thrombi in giant right CAE. Thrombus aspiration during percutaneous intervention may limited cases, and systemic thrombolysis effective
Amiodarone is an effective antiarrhythmic drug. However, it associated with changes in thyroid function euthyroid patients due to its high iodine content and intrinsic drug effects. Studies have been conducted iodine-deficient iodine-sufficient countries; however, data from countries excessive intake are lacking. Thus, this study aimed evaluate the effect of long-term amiodarone treatment on Japanese patients. adults aged ≥18 years who were treated for at least 90 consecutive days included...
A 61-year-old woman had an intracranial tumour that was located on the falx. Meningioma suspected and rapidly grew over 1 year. It showed nearly equal density with spinal fluid showing almost no enhancement radiographic images, like microcystic meningioma. Successful removal of achieved. Histopathologically, diagnosed as low-grade The meningioma variable sized microcysts appearance solid area meningothelial This is a rare image for
During the coronavirus disease 2019 pandemic, Japanese Society of Diabetes and Pregnancy proposed use random plasma glucose glycated hemoglobin measured 1 month after delivery combined with pre-pregnancy body mass index to detect postpartum intolerance instead carrying out oral tolerance test in women gestational diabetes. We retrospectively evaluated clinical utility this strategy by delivery. A total 275 diabetes were included present study. The specificity 1-month predict was 98.0%, a...
A 41-year-old woman was admitted to the obstetrics department because of epigastric pain, nausea, and fatigue at 31 weeks gestation. She suspected subclinical Cushing's syndrome based on high plasma cortisol low ACTH levels along with an incidentally discovered tumor in left adrenal gland 4 years prior conception. 3 months before admission, 75 g oral glucose tolerance test yielded one point positive (81–169–174 mg/dL) diagnosis gestational diabetes mellitus made. Diet exercise therapy...
AimsTo evaluate the efficacy and safety of switching to insulin glargine 300 U/mL (Gla-300) from 100 (Gla-100) in Japanese patients with type 2 diabetes (T2DM).MethodsThis was a 12-month retrospective study comprising 109 patients. Primary endpoint glycated hemoglobin (HbA1c) level at month 12. Secondary endpoints were hypoglycemia for overall period as well body weight dose 12.ResultsSimilar glycemic control achieved mean (standard deviation) HbA1c 7.7 (1.1)% (61 [12] mmol/mol) baseline...
ニワトリの人為的な性転換の方法を検討するために,発生初期胚への精巣の移植が雌胚の生殖器官に及ぼす影響を調べた。孵卵13日目の白色レグホーン種の雄胚から得た精巣を,孵卵3日目の名古屋種雄と横斑プリマスロック種雌とのF1の受精卵の胚体外体腔に移植した。移植した精巣に対する血管の新生は,移植後2日目に観察した。移植10日目または13日目に胚の生殖器官を観察したところ,血管の新生が認められた雌胚のうち約2/3ではミューラー管が左右ともに消失しており,また左右性腺の萎縮の程度はさまざまであった。強度の萎縮が認められた性腺には精巣様の管状組織が観察された。萎縮した性腺のテストステロンおよびエストラジオール-17β産生能をin vitroで測定した結果,萎縮が軽度の場合は正常な同時期の卵巣と比較して有意な差はなかった。しかし,萎縮が強度の場合には,卵巣の産生量より有意に少なくなっており,同時期の正常な精巣の産生量とほぼ同等であった。これらの結果から,13日齢の精巣はミューラー管の萎縮を促す物質を分泌することを示すとともに,未分化の性腺に作用してこれを精巣様に分化させるような物質を分泌することが示唆された。