Naotaka Okamoto
A5015963776- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Peripheral Artery Disease Management
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Venous Thromboembolism Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Aortic aneurysm repair treatments
- Optical Coherence Tomography Applications
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Vascular Procedures and Complications
- Lipoproteins and Cardiovascular Health
- Cardiac Arrest and Resuscitation
- Protease and Inhibitor Mechanisms
- Cardiovascular Disease and Adiposity
- Fatty Acid Research and Health
- Electrolyte and hormonal disorders
Osaka Rosai Hospital
2015-2025
Icahn School of Medicine at Mount Sinai
2017-2025
Mount Sinai Hospital
2017-2022
Mount Sinai Medical Center
2019-2020
Mount Sinai Hospital
2019-2020
Nagasaki Rousai Hospital
2015
National Cancer Centre Japan
2013
AimsAlthough dietary saturated fatty acids (SFA) are considered atherogenic, associations between SFAs intake and stroke coronary heart disease still debated. We sought to test the hypothesis that SFA is associated inversely with risk of its subtypes positively among Japanese, whose average lower than Westerners.
Several studies have shown the serum high sensitive cardiac troponin I (hs-TnI) a biomarker of myocardium injury, and C-reactive protein (CRP), inflammation, are associated with worse cardiovascular outcomes. We evaluated relationship between hs-TnI level in patients paroxysmal atrial fibrillation (PAF) after pulmonary vein isolation (PVI) (AF) recurrence.We enrolled 263 consecutive PAF who underwent PVI from May 2017 to April 2018. investigated difference myocardial injury marker (serum...
Background An association between uric acid (UA) and cardiovascular diseases, including heart failure (HF), has been reported. However, whether UA is a causal risk factor for HF controversial. In particular, the prognostic value of lowering in patients with preserved ejection fraction (HFpEF) unclear. Methods Results We enrolled HFpEF from PURSUIT‐HFpEF (Prospective Multicenter Observational Study Patients With Heart Failure Preserved Ejection Fraction) registry. investigated was correlated...
We sought to evaluate procedural complications and one-year clinical outcomes for patients who underwent percutaneous coronary intervention (PCI) with orbital (OA) rotational atherectomy (RA).From a total of 13,467 PCI in our hospital between January 2013 June 2016, 1,149 consecutive were treated moderately-severely calcified lesions (184 OA, 965 RA). Procedural similarly observed the two groups except higher dissection perforation rates OA. Major adverse cardiovascular events (MACE) defined...
Background: There is a paucity of data on the effect optimal intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) compared with standard PCI or artery bypass grafting (CABG) in patients multivessel disease.
Abstract Background Little is known about intravascular imaging predictors of cardiac events after drug‐eluting stent (DES) implantation in hemodialysis (HD) patients. We aimed to reveal the association between calcified nodules (CN) and target lesion failure (TLF) HD patients DES implantation. Methods enrolled 114 who underwent October 2016 2020. The were divided into a CN group (39%, 44 patients) non‐CN (61%, 70 patients). primary endpoint was incidence TLF, including death, vessel...
Purpose: We designed a study investigating the cardioprotective role of sleep apnea (SA) in patients with acute myocardial infarction (AMI), focusing on its association infarct size and coronary collateral circulation. Methods: recruited adults AMI, who underwent Level-III SA testing during hospitalization. Delayed-enhancement cardiac magnetic resonance (CMR) imaging was performed to quantify AMI (percent-infarcted myocardium). Rentrop Score quantified collateralization (scores 0– 3, higher...
There are few studies regarding the predictors of stent underexpansion (SUE) in post-debulking calcified lesions. We investigated SUE severely lesions after debulking using optical coherence tomography-guided rotational atherectomy (RA) or orbital (OA). As a post hoc analysis DIRO trial, we compared various parameters, including calcium and lipid parameters (lipid-rich plaque, thin cap fibroatheroma [TCFA], maximum arc, mean length, volume index), between groups with adequate expansion (ASE)...
Abstract Aims The impacts of high density lipoprotein cholesterol (HDL‐C) as an anti‐inflammatory and C reactive protein (CRP) inflammatory properties on the pathogenesis heart failure were reported. At present, clinical significance HDL‐C/CRP ratio in with preserved ejection fraction (HFpEF) patients remains unknown. Methods results We examined data 796 consecutive HFpEF (left ventricular ≥50%) hospitalized due to acute decompensated from PURSUIT‐HFpEF registry, a prospective, multicentre...
ABSTRACT Background The changes over time and effects on long‐term clinical outcomes beyond 1 year of irregular protrusion (IP) in chronic coronary syndrome (CCS) remains unclear. Aims This study aimed to assess the time‐dependent change impact IP CCS lesions. Methods was a post hoc analysis COLLABORATION study, which multicenter, prospective, observational conducted from July 2018 February 2020, assessing 1‐ 12‐month serial vessel responses after stent implantation using OCT angioscopy....
Seafood/fish intake has been regarded as a protective factor for coronary heart disease (CHD), while smoking is strong risk factor. To examine whether associations between and of CHD are modified by seafood/fish intake, we studied 72,012 Japanese men women aged 45–74 years who completed 2 food frequency questionnaires, 5 apart, during the period 1995–2009. After 878,163 person-years follow-up, 584 incident cases (101 fatal 483 nonfatal), including 516 myocardial infarctions, were documented....
Abstract Aims Low‐density lipoprotein cholesterol (LDL‐C), anaemia and low platelets have been associated with worse clinical outcomes in heart failure patients. We investigated the relationship between combination of these three components outcome patients preserved ejection fraction (HFpEF). Methods results examined data 1021 HFpEF hospitalized acute decompensated (HF) from PURSUIT‐HFpEF registry, a prospective, multicenter observational study. The enrolled were classified into four groups...