A5102806274- Algal biology and biofuel production
- Biofuel production and bioconversion
- Postharvest Quality and Shelf Life Management
- Nanocomposite Films for Food Packaging
- Muscle Physiology and Disorders
- Biodiesel Production and Applications
- Mitochondrial Function and Pathology
- Microbial Metabolic Engineering and Bioproduction
- Photosynthetic Processes and Mechanisms
- Bone and Dental Protein Studies
- Tissue Engineering and Regenerative Medicine
- Cardiomyopathy and Myosin Studies
- Anorectal Disease Treatments and Outcomes
- Food Chemistry and Fat Analysis
- Genetic and Kidney Cyst Diseases
- RNA modifications and cancer
- Cancer, Lipids, and Metabolism
- Aquatic Ecosystems and Phytoplankton Dynamics
- Bone Tissue Engineering Materials
- Ferroptosis and cancer prognosis
- Proteins in Food Systems
- Microbial Inactivation Methods
- Periodontal Regeneration and Treatments
- Ferrocene Chemistry and Applications
- Optical and Acousto-Optic Technologies
Peking University
2024-2025
Guangzhou Medical University
2024-2025
Hunan University
2024-2025
Hunan Academy of Agricultural Sciences
2024
Agency for Science, Technology and Research
2017-2024
Institute of Molecular and Cell Biology
2017-2024
Henan University of Science and Technology
2024
Luoyang Institute of Science and Technology
2024
First Affiliated Hospital of Zhengzhou University
2023
Zhengzhou University
2023
Glucose-dependent insulinotropic peptide (GIP) is a 42-amino acid synthesized and secreted from endocrine cells in the small intestine. The role of GIP coupling nutrient intake insulin secretion, incretin effect, well known. We report that receptor messenger RNA protein are present normal bone osteoblast-like cell lines, high affinity receptors for can be demonstrated by [125I]GIP binding studies. When applied to (SaOS2), stimulated increases cellular cAMP content intracellular calcium, with...
Vibrio species, the Gram-negative bacterial pathogens causing cholera and sepsis, produce multiple secreted virulence factors for infection pathogenesis. Among these is multifunctional-autoprocessing repeats-in-toxin (MARTX) toxin that releases several critical effector domains with distinct functions inside eukaryotic host cells. One such domain, Rho inactivation domain (RID), has been discovered to catalyze long-chain N
Abstract A cell carrier plays an important role in the maintenance, growth and engraftment of specific cells aimed for defined therapeutic uses many tissue engineering strategies. suitable microenvironment allows maximum efficacy hybrid device. We have prepared injectable thermosensitive chitosan/β‐glycerophosphate/collagen (C/GP/Co) gel investigated its potential application as a support culture skeletal muscle satellite (SMSCs). viability assay was used to evaluate vitro cytocompatibility...
To successfully metastasize, cancer cells must evade detachment induced cell death, known as anoikis. Unraveling the mechanisms that gastric (GC) circumvent anoikis and achieve peritoneal metastasis especially during unanchored growth, could significantly improve patient outcomes. Our study reveals GC exhibit increased lipid peroxidation, MDA production, death suspension culture, which can be mitigated by intervention with liproxstatin-1 ferrostatin-1. We discovered oleic acid (OA) or...
Defatted walnut residues (DWR) were hydrolysed using Bacillus subtilis to produce angiotensin-I-converting enzyme (ACE) inhibitory peptides. Fermented residue extract (FWRE) was fractionated ultrafiltration methods identify the ACE-inhibitory The fraction with a molecular weight of <1 kDa (WPs-I) presented greatest activity. Reverse-phase high-performance liquid chromatography used separate WPs-I from most active fractions, and amino acid sequence confirmed as VQTL (459.351 Da) LGYEN...
Lasp-1 (LIM and SH3 domain protein 1) is a multidomain actin-binding that differentially expressed within epithelial tissues brain. In the gastric mucosa, highly in HCl-secreting parietal cell, where it prominently localized F-actin-rich subcellular regions. Histamine-induced elevation of cell [cAMP]i increases phosphorylation, which correlated with activation HCl secretion. To determine whether involved regulation secretion vivo, we generated murine model targeted disruption gene....
Pathogenic Yersinia bacteria cause a range of human diseases. To modulate and evade host immune systems, these yersiniae inject effector proteins into macrophages. One such protein, the serine/threonine kinase YopO (YpkA in pestis), uses monomeric actin as bait to recruit phosphorylate polymerization-regulating proteins, including actin-severing protein gelsolin, disrupt filaments thus impair phagocytosis. However, phosphorylation sites on gelsolin consequences YopO-mediated remodeling have...
A major goal for X-ray free-electron laser (XFEL) based science is to elucidate structures of biological molecules without the need crystals. Filament systems may provide some first single macromolecular elucidated by XFEL radiation, since they contain one-dimensional translational symmetry and thereby occupy diffraction intensity region between extremes crystals molecules. Here, we demonstrate flow alignment as few 100 filaments (Escherichia coli pili, F-actin, amyloid fibrils), which when...