- Ultrasound Imaging and Elastography
- Photoacoustic and Ultrasonic Imaging
- Ultrasound and Hyperthermia Applications
- Radiomics and Machine Learning in Medical Imaging
- Thyroid Cancer Diagnosis and Treatment
- Immune Cell Function and Interaction
- Reproductive System and Pregnancy
- Pancreatic and Hepatic Oncology Research
- Eosinophilic Esophagitis
- Gastroesophageal reflux and treatments
- Immune Response and Inflammation
- Helicobacter pylori-related gastroenterology studies
- Ultrasound and Cavitation Phenomena
- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- Neuroendocrine Tumor Research Advances
- Ultrasonics and Acoustic Wave Propagation
- Blood properties and coagulation
- Gastrointestinal motility and disorders
- Elasticity and Material Modeling
- Scoliosis diagnosis and treatment
- T-cell and B-cell Immunology
- MRI in cancer diagnosis
- Erythrocyte Function and Pathophysiology
- Spinal Fractures and Fixation Techniques
Ruijin Hospital
2010-2025
Westlake University
2025
Wenzhou Medical University
2025
Hangzhou First People's Hospital
2025
Shanghai Jiao Tong University
2014-2024
Tongren Hospital
2016-2024
Zhejiang Chinese Medical University
2024
Smith-Kettlewell Eye Research Institute
2023
Stanford University
2021-2023
Shenzhen University
2014-2023
Elastography ultrasound (EUS) imaging is a vital modality. The current use of EUS faces many challenges, such as vulnerability to subjective manipulation, echo signal attenuation, and unknown risks elastic pressure in certain delicate tissues. hardware requirement also hinders the trend miniaturization equipment. Here we show cost-efficient solution by designing deep neural network synthesize virtual (V-EUS) from conventional B-mode images. A total 4580 breast tumor cases were collected 15...
Diffusion-weighted imaging (DWI)-based virtual MR elastography (DWI-vMRE) in the assessment of breast lesions is still research stage.
Paclitaxel (PTX) is one of the most widely used clinical antitumour drugs in chemotherapy nowadays. Its effect on immune system has become a hot spot research recent years. Here, we demonstrated that PTX not only decreased percentage CD4+Foxp3+ regulatory T (Treg) cells both vitro and vivo but also impaired cell viability cytokine production Treg rather than CD4+Foxp3- effector (Teff) cells. As been reported to mimic activity LPS trigger toll-like receptor 4 (TLR4) signalling pathway...
To evaluate inter- and intra- scan mode scanner repeatability reproducibility of radiomics features within between single-energy CT (SECT) dual-energy (DECT).A standardized phantom with sixteen rods clinical-relevant densities was scanned on seven DECT-capable scanners three SECT-only scanners. The acquisition parameters were selected to present typical abdomen-pelvic examinations the same voxel size. Images SECT at 120 kVp corresponding kVp-like virtual monochromatic images (VMIs) in DECT...
This paper presents the use of hydrodynamic cavitation and ultrasonic technologies for treating rhodamine B (RhB) in simulated wastewater. Various parameters each technology that influence RhB degradation rate were compared optimized. The results showed optimal conditions determined by single-factor method as follows: inlet pressure, 0.4 MPa; initial concentration, 10 mg L-1; reaction temperature, 30 °C; pH value, 3. was 38.7%. In addition, response surface methodology power, 850 W; time,...
A growing body of evidence links chronic obstructive pulmonary disease (COPD) to gastroesophageal reflux (GERD). In spite the lack understanding specific cause-effect relationship between COPD and GERD, GERD has been shown be a significant predictor acute exacerbations COPD. this study, we examined evolution over past decades provided valuable insights into topic.The Web Science Core Collection (WoSCC) was searched since its inception until 19 August 2022 obtain publications related GERD....
Cardiac arrest (CA) is associated with high incidence and mortality rates. Hence, assessing the prognosis of CA patients crucial for optimizing clinical treatment. This study aimed to develop validate a clinically applicable nomogram predicting risk in-hospital in patients. We retrospectively collected data admitted two hospitals Zhejiang Province between January 2018 June 2024. These were randomly assigned training set (70%) internal validation (30%). Variables interest included...
The microRNA miR-221-3p has previously been found to be an underlying biomarker of pancreatic cancer. However, the mechanisms its role in cancer pathogenesis, proliferation capability, invasion ability, drug resistance and apoptosis clinicopathological value have not thoroughly studied.Based on microarray miRNA-sequencing data extracted from Gene Expression Omnibus (GEO), Cancer Genome Atlas (TCGA), relevant literature, real-time quantitative PCR (RT-qPCR), we explored features expression...
Objectives To compare the sonographic results, clinicopathologic characteristics, and biomarkers in pure ductal carcinoma situ (DCIS) of breast DCIS with microinvasion. Methods A total 218 patients pathologically proven based on sonography our hospital (2009–2013) were retrospectively enrolled. Clinicopathologic characteristics examined. Grayscale results investigated according to American College Radiology Breast Imaging Reporting Data System lexicon, color Doppler was used assess...
Axillary lymph node (ALN) status is a key prognostic factor in patients with early-stage invasive breast cancer (IBC). The present study aimed to develop and validate nomogram based on multimodal ultrasonographic (MMUS) features for early prediction of axillary metastasis (ALNM). A total 342 IBC (240 the training cohort 102 validation cohort) who underwent preoperative conventional ultrasound (US), strain elastography, shear wave elastography contrast-enhanced US examination were included...
Wnt1 inducible signaling pathway protein-1 (WISP1) may play an important role in promoting carcinogenesis. However, the biological function and underlying mechanism of WISP1 pancreatic carcinogenesis still remains enigmatic. In this study, immunochemistry staining showed that protein levels were more significantly upregulated ductal adenocarcinoma (PDAC) tissues with Tp53 mutation than PDAC wild-type. addition, a significant correlation was observed between increased malignant phenotype...
BACKGROUND The objective of this study was to compare the sampling efficiency ultrasound‐guided fine‐needle aspiration (FNA) and capillary (FNC) in thyroid nodules, which authors specifically analyzed influence nodule size. METHODS This included 280 nodules 275 consecutive patients. were divided into 4 size subgroups: ≤5.0 mm, from 5.1 10.0 10.1 20.0 >20.0 mm. Each sampled by both FNA FNC. final cytopathologic findings reported. smears scored then categorized as diagnostically inadequate,...
Acupuncture is therapeutic for refractory gastroesophageal reflux disease by an unclear mechanism. This study was aimed at investigating the effect of acupuncture on esophageal motility in patients with symptoms disease. Sixty-eight were prospectively enrolled from August 2014 to December 2018 and randomized into control groups (n = 33 35, respectively). The group received acupuncture, sham acupuncture. Pre- post-acupuncture high-resolution manometry performed evaluate motility. GerdQ...