A5106454325- Spectroscopy and Chemometric Analyses
- Spectroscopy Techniques in Biomedical and Chemical Research
- Traditional Chinese Medicine Analysis
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Ginkgo biloba and Cashew Applications
- Water Quality Monitoring and Analysis
- Natural Compound Pharmacology Studies
- Phytochemical Studies and Bioactivities
- Additive Manufacturing Materials and Processes
- Neurological Disease Mechanisms and Treatments
- Hepatitis C virus research
- Medicinal Plant Pharmacodynamics Research
- Cholesterol and Lipid Metabolism
- Diabetes Treatment and Management
- Cognitive Radio Networks and Spectrum Sensing
- Bioactive Natural Diterpenoids Research
- Lipid Membrane Structure and Behavior
- Flavonoids in Medical Research
- Morinda citrifolia extract uses
- Ginseng Biological Effects and Applications
- Chemotherapy-induced cardiotoxicity and mitigation
- Biochemical Acid Research Studies
- Biochemical and Molecular Research
- Chromatography in Natural Products
Changchun University of Chinese Medicine
2013-2024
Lishui University
2022-2024
Yunnan University of Traditional Chinese Medicine
2024
Coventry University
2023
Qiqihar Medical University
2021
Hangzhou Hospital of Traditional Chinese Medicine
2021
Xian Central Hospital
2019
Zhejiang University
2011-2017
China Pharmaceutical University
2016
State Council of the People's Republic of China
2016
The aim of this study was to develop an optimal niosomal system deliver Ginkgo biloba extract (GbE) with improved oral bioavailability and replace the conventional GbE tablets.In study, film dispersion-homogenization method used prepare niosomes. resulting niosome suspension freeze-dried or spray-dried improve stability GbE-loaded niosomes were formulated characterized in terms their morphology, particle size, zeta potential, entrapment efficiency, angle repose, differential scanning...
Madecassoside (MA), a triterpenoid saponin isolated from C. asitica, exerts various pharmacological activity including antioxidative and antinflammatory. Doxorubicin (DOX), common chemotherapeutic drug, has been reported to induce numerous toxic side effects renal-toxicity. We hypothesized that MA administration may decrease renal-toxicity caused by DOX. In this study, we investigated hypothesis introducing DOX into the culture of Human Proximal Tubule Cells HK-2 mice model. Our in vivo...
It has been shown that modestly increasing plasma membrane cholesterol beyond its physiological set point greatly increases the endoplasmic reticulum and mitochondrial pools, thereby eliciting manifold feedback responses return cell to resting state. The question arises whether this homeostatic mechanism reflects targeting of surface specific intracellular sites or general equilibration among organelles. We now show human fibroblast can be increased as much two-fold from...
Akebia saponin D (ASD) exerts various pharmacological activities but with poor oral bioavailability. In this study, a self-nanoemulsifying drug delivery system (SNEDDS) based on the drug-phospholipid complex technique was developed to improve absorption of ASD.ASD-phospholipid (APC) prepared using solvent-evaporation method and characterized by infrared spectroscopy, differential scanning calorimetry, morphology observation, solubility test. Oil cosurfactant were selected according their...
Abstract Additive manufacturing (AM) of Al–Mg–Sc alloys has received considerable interest from the aerospace industry owing to their high specific strength and suitability for AM processes. This study investigated fatigue crack growth behavior in an Al–Mg–0.3Sc alloy made by wire arc additive manufacturing. Tests were conducted with two different orientations at cyclic load ratios 0.1 0.5. At lower ratio, horizontal showed a faster rate smaller grains coarser second‐phase particles that tip...
A simple and reliable method of high-performance liquid chromatography with diode array detection was developed for fingerprint analysis simultaneous determination six compounds including puerarin, salvianolic acid B, berberine hydrochloride, palmatine chloride, dehydrocorydaline, icariin in the Chinese medicine preparation Yangxinshi Pian. The separation performed on an Agilent Eclipse XDB-C18 reserved-phase column (250 mm × 4.6mm I.D., 5 μm) using gradient elution 50 mmol/L monopotassium...
Akebia saponin D (ASD) exhibits a variety of pharmacological activities, such as anti-osteoporosis, neuroprotection, hepatoprotection, but has poor oral bioavailability. A self-nanoemulsifying drug delivery system loaded with akebia - phospholipid complex (APC-SNEDDS) (composition: Peceol: Cremophor® EL: Transcutol HP: ASD: phospholipid; ratio: 10:45:45:51:12.3, w:w:w:w:w) was first developed to improve the absorption saponins and it found significantly enhance ASD's bioavailability by 4.3...
As a rapid and accurate technique, near infrared (NIR) spectroscopy has been widely used in process monitoring to improve efficiency ensure quality consistency. In the present work, application of NIR for on-line quantitative concentration Wangbi tablets was investigated. Partial least squares regression (PLSR) models based on full-range spectra or key wavelengths selected by competitive adaptive reweighted sampling (CARS) method were established. The accuracy CARS-PLSR greater than that...
This paper used near-infrared (NIR) spectroscopy for the on-line quantitative monitoring of water precipitation during Danhong injection. For these NIR measurements, two fiber optic probes designed to transmit radiation through a 2 mm flow cell were collect spectra in real-time. Partial least squares regression (PLSR) was developed as preferred chemometrics analysis critical intermediate qualities: danshensu (DSS, (R)-3, 4-dihydroxyphenyllactic acid), protocatechuic aldehyde (PA), rosmarinic...
Abstract In this study, the application of near‐infrared (NIR) spectroscopy for online monitoring Moluodan extraction process was investigated. Paeoniflorin, main active component Moluodan, chosen as quality index. Samples were partitioned into calibration and validation sets by random select set partitioning based on joint X‐Y distances algorithm (SPXY), respectively. Wavelengths modeling selected manual method competitive adaptive reweighted sampling (Cars) algorithm. Particle swarm...
Akebia saponin D (ASD), a triterpenoid with numerous pharmacological activities, is isolated from the rhizome of <italic>Dipsacus asper</italic> Wall.