- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Wound Healing and Treatments
- Cancer-related molecular mechanisms research
- Epigenetics and DNA Methylation
- MicroRNA in disease regulation
- Cancer-related gene regulation
- Inflammatory Bowel Disease
- Mesenchymal stem cell research
- Neonatal Respiratory Health Research
- Antimicrobial Peptides and Activities
- dental development and anomalies
- Pressure Ulcer Prevention and Management
- Circular RNAs in diseases
- Seaweed-derived Bioactive Compounds
- Extracellular vesicles in disease
- Burn Injury Management and Outcomes
- Autophagy in Disease and Therapy
- Skin and Cellular Biology Research
- Nanoplatforms for cancer theranostics
- Congenital Ear and Nasal Anomalies
- Fibroblast Growth Factor Research
- Systemic Lupus Erythematosus Research
- Gut microbiota and health
- Cancer Cells and Metastasis
Shantou University
2016-2025
Shantou University Medical College
2013-2025
Second Affiliated Hospital of Shantou University Medical College
2016-2025
Leeds Teaching Hospitals NHS Trust
2024
Institute of Botany
2023-2024
Chinese Academy of Sciences
2017-2024
Nanjing Medical University
2024
Nanjing University
2024
Nanjing General Hospital of Nanjing Military Command
2024
Sichuan University
2023
A randomized, open-label comparative study of entecavir versus adefovir therapy was performed in subjects with chronic hepatitis B who had hepatic decompensation (Child-Turcotte-Pugh score ≥7). Adult were randomized and treated (n = 191) 1.0 mg or 10 daily for up to 96 weeks from the date last subject randomization. Subjects positive negative e antigen experienced naive treatment nucleos(t)ide analogues. The primary efficacy endpoint mean reduction serum virus (HBV) DNA, as determined by...
Polysaccharide-based hydrogels have been developed for many years to treat burn wounds. Essential oils extracted from aromatic plants generally exhibit superior biological activity, especially antibacterial properties. Studies shown that mixed with essential great potential wound healing. This study aimed develop an polysaccharide-based hydrogel oil skin repair.Eucalyptus (EEO), ginger (GEO) and cumin (CEO) were employed the preparation of effective physically crosslinked by carboxymethyl...
HP1γ, encoded by CBX3, is associated with cancer progression and patient prognosis. However, the prognostic value functions of CBX3/HP1γ in hepatocellular carcinoma (HCC) remain unclear. Here, we performed a bioinformatics analysis using Oncomine, TCGA Human Protein Atlas databases, Kaplan-Meier plotter, UALCAN web-portal to explore expression significance patients different cancers, including liver cancer. HCC tissues microarrays containing 354 samples were examined immunohistochemical...
Abstract Brown seaweed polysaccharides (BSPs) are one of the primary active components from brown that has a range pharmaceutical and biomedical applications. However, quality control BSPs is challenge due to their complicated structure macromolecule. In this study, saccharide mapping based on high-performance liquid chromatography (HPLC), multi-angle laser light scattering, viscometer, refractive index detector (HPSEC-MALLS-Vis-RID), Fourier transform infrared (FT-IR) were used discriminate...
Gracilaria lemaneiformis polysaccharide (GLP) has varieties of antioxidation, however, the therapeutic effects GLP on ulcerative colitis (UC) and potential mechanisms involved are still incomplete. In study, analysis ζ-potential, thermal, morphology properties demonstrated that was a negatively charged polymer, had great thermostability irregular network. Moreover, treatment reducing severity caused by dextran sulfate sodium alleviating colon damage mice, increasing amount short-chain fatty...
Skin cutaneous melanoma (SKCM) is the world's fourth deadliest cancer, and advanced SKCM leads to a poor prognosis. Novel biomarkers for diagnosis prognosis are urgently needed. Long non-coding RNAs (lncRNAs) provide various biological functions have been proved play significant role in tumor progression. Single-cell RNA sequencing (scRNA-seq) enables genome analysis at single-cell level. This study explored prognostic lncRNAs based on scRNA-seq bulk data.The TCGA cohort samples GEO database...
The behavior of cage-reared ducks is an important index to judge the health status laying ducks. For automatic recognition task duck based on machine vision, by comparing detection performance YoloV4 (you only look once), YoloV5, and Faster-RCNN, this work selected YoloV5 target network with best identify three behaviors related avoidance after a emergency. average precision was 98.2% (neck extension), 98.5% (trample), 98.6% (spreading wings), respectively, speed 20.7 FPS. Based model, in...
Microplastics and nanoplastics (MPs/NPs) are posing emerging potential threats to global ecosystems human health. Recently, the individual effects of MPs/NPs combined MPs/NPs-coexisting pollutants on soil–terrestrial plant systems have attracted increasing attention. Based latest research progress, this review firstly summarized sources interaction between coexisting in soil environment, then systematically induced their multilevel impacts properties terrestrial plants. Soil agroecosystem...
Retinoic acid (RA) contributes to cleft palate; however, the cellular and molecular mechanisms responsible for deleterious effects on developing palate are unclear. Wnt signaling is a candidate pathway in associated with RA organ development; thus, we aim investigate whether RA-induced also results from altered signaling. Administration of mice cell proliferation apoptosis craniofacial tissues by regulating molecules controlling cycle p38 MAPK signaling, respectively. This fate crucial...
Abstract Background A chromobox homologue 3 (CBX3) is elevated in various cancers and significantly contributes to the promotion of malignant behavior; despite this, its exact involvement clear cell renal carcinoma (ccRCC) yet unknown. Methods The Cancer Genome Atlas database served evaluate CBX3 production connection survival patients with ccRCC. Our team evaluated effects knockdown levels ccRCC populations using vitro together vivo models. CBX3, proteins related death,...
// Ke Cao 1, * , Jingjing Li 2, Jia Chen Qian 3 Aijun Wang 4 Xiang 5 Wei Xiong 6 Jintian Tang 7 Shijie 8 Yong 9 Yao 2 Yan Cheng 10 and Jianda Zhou 1 Department of Oncology Third Xiangya Hospital, Central South University, Changsha, China Plastic Surgery Burn Second Surgical Bioengineering Laboratory, Surgery, UC Davis School Medicine, Sacramento, California, USA Dermatology Cancer Research Institute, Key Laboratory Carcinogenesis Ministry Health, Institute Medical Physics Engineering,...
The causal relationship between vitamins supplementation and the risk of skin cancers remains unclear. We conducted a Mendelian randomization study to assess associations in general population. aimed investigate (A-E) with using utilizing linkage disequilibrium score regression (LDSC) (MR). selected genome-wide significant single-nucleotide polymorphisms (SNPs) linked vitamin supplements (A-E). Summary-level data for melanoma, basal cell carcinoma, squamous carcinoma were obtained from...
Abstract The current Ethanol-water Exchange method utilizes an offline bubble size measurement technique, which is unable to monitor the process of stabilization in real time. Therefore, this paper proposes online technology for variation bubbles with directional flow during nanobubble displacement generation process. In context, a sample cell capable was designed, and dynamic light scattering (DLS) device capabilities constructed. Regarding measurement, DLS technique refined using...