- Genomics and Phylogenetic Studies
- Identification and Quantification in Food
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Aquaculture disease management and microbiota
- Genetic diversity and population structure
- Cancer-related molecular mechanisms research
- Forensic Anthropology and Bioarchaeology Studies
- Ichthyology and Marine Biology
- Viral Infectious Diseases and Gene Expression in Insects
- Air Quality and Health Impacts
- Mitochondrial Function and Pathology
- Enzyme Catalysis and Immobilization
- Biofuel production and bioconversion
- Parkinson's Disease Mechanisms and Treatments
- Immune cells in cancer
- Microbial Metabolic Engineering and Bioproduction
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Plant Molecular Biology Research
- RNA modifications and cancer
- Plant Gene Expression Analysis
- RNA regulation and disease
- Amyotrophic Lateral Sclerosis Research
- Cocoa and Sweet Potato Agronomy
- Clinical Nutrition and Gastroenterology
University of South China
2017-2025
Shanghai Academy of Agricultural Sciences
2019-2024
Ocean University of China
2024
Hengyang Academy of Agricultural Sciences
2024
Northwest A&F University
2024
Qingdao National Laboratory for Marine Science and Technology
2022-2023
First Institute of Oceanography
2012-2023
Ministry of Natural Resources
2021-2023
Horticultural Research Institute
2023
Xinxiang Medical University
2023
An Integrated Vacuum Carbonate Absorption Process (IVCAP) for post-combustion carbon dioxide (CO2) capture is described. IVCAP employs potassium carbonate (PC) as a solvent, uses waste or low quality steam from the power plant CO2 stripping, and biocatalyst, carbonic anhydrase (CA) enzyme, promoting absorption into PC solution. A series of experiments were performed to evaluate activity CA enzyme mixed in solutions stirred tank reactor system under various temperatures, dosages, loadings,...
Thorium (Th) is a natural radioactive element present in the environment and has potential to be used as nuclear fuel. Relatively little known about influence toxicity of Th environment. In study, green algae Chlorella pyrenoidosa (C. pyrenoidosa) was evaluated by algal growth inhibition, biochemical assays morphologic observations. cultural medium (OECD TG 201), Th(NO₃)₄ transformed amorphous precipitation Th(OH)₄ due hydrolysis. toxic C. pyrenoidosa, with 96 h half maximum effective...
Abstract Colorectal cancer is the second common cause of death worldwide. Lamin B2 (LMNB2) involved in chromatin remodeling and rupture reorganization nuclear membrane during mitosis, which necessary for eukaryotic cell proliferation. However, role LMNB2 colorectal (CRC) poorly understood. This study explored biological functions progression possible molecular mechanisms. We found that was significantly upregulated primary tissues lines, compared with paired non-cancerous normal epithelium....
Abstract Fine particulate matter (PM2.5) exposure is significantly linked to lung epithelial cell senescence, and autophagy dysfunction being a key contributor the aging process. Although anti-aging properties of ellagic acid (EA) are well-documented, its specific protective effect on PM2.5-induced senescence still needs be studied in depth. To investigate impacts PM2.5 cells, 16HBE A549 cells were exposed suspension. Additionally, explore potential intervention EA, pretreated with EA before...
Beryllium and its compounds are classified as carcinogens, prolonged exposure can trigger chronic beryllium disease. The Janus kinase-signal transducer activator of transcription (JAK-STAT) signaling is known to play a critical role in the development progression numerous diseases. Leukemia inhibitory factor (LIF), key upstream cytokine JAK-STAT pathway, has been implicated regulating inflammatory responses epithelial-mesenchymal transition (EMT) various However, specific involvement pathway...
ABSTRACT Beryllium (Be) is a recognised environmental toxicant associated with pulmonary fibrosis. Epithelial–mesenchymal transition (EMT), critical process in cell phenotype conversion, plays key role its pathophysiology. Methyltransferase‐like 3 (METTL3), major N6‐methyladenosine methyltransferase, regulates gene expression and cellular functions. However, Be‐induced EMT remains unclear. In this study, human bronchial epithelial line (16HBE cells) were exposed to varying concentrations of...
Abstract Apple Glomerella leaf spot (GLS) is an emerging fungal disease caused by Colletotrichum fructicola and other species. These species are polyphyletic it currently unknown how these pathogens convergently evolved to infect apple. We generated chromosome‐level genome assemblies of a GLS‐adapted isolate non‐adapted in C. using long‐read sequencing. Additionally, we resequenced 17 aenigma isolates varying GLS pathogenicity short‐read Genome comparisons revealed conserved bipartite...
Abstract Background Chronic beryllium disease is characterized by granulomas and pulmonary fibrosis. Recent studies have shown that microRNAs (miRNAs) circular RNAs (circRNAs) play critical roles in the pathogenesis development of many diseases. However, role miRNAs circRNAs fibrosis induced sulfate (BeSO4) has not been elucidated. Methods Previous demonstrated hsa-miR-663b was down-regulated 150 μmol/L BeSO4-treated 16HBE cells, while hsa_circ_ 0004214 up-regulated. Here we found...
Understanding the genetic structure and local adaptive evolutionary mechanisms of marine organisms is crucial for management biological resources. As ecologically commercially important small-sized shallow-sea fish, Collichthys lucidus plays a vital role in functioning ecosystem processes. C. has been shown to have an obvious population structure. Therefore, it ideal candidate investigating differentiation adaptation under heterogeneous environmental pressure.A total 184,708 high-quality...
Abstract Beryllium sulfate (BeSO 4 ) can result to lung injuries, such as leading lipid peroxidation and autophagy, the treatment of beryllium disease has not been well improved. Ferroptosis is a regulated cell death process driven by iron‐dependent peroxidation, while ferritinophagy mediated nuclear receptor coactivator (NCOA4), combined with ferritin heavy chain 1 (FTH1) degradation release Fe 2+ , which intracellular iron metabolism ferroptosis. Hydrogen sulfide (H 2 S) effects...
Recent studies revealed a causal relationship between Toll-like receptors (TLRs) and lipid droplet biogenesis. Interestingly, it has been reported before that nanomaterials (NMs) were capable to modulate TLRs, but remains unclear if NMs could affect levels via TLR signaling pathways. In this study, we investigated the influences of airway exposure graphene oxide (GO) on TLR3 pathways in mouse livers. Intratracheal instillation GO (0.1, 1, 5 mg/kg, once day, totally days) induced inflammatory...
Fructosyltransferases have been used in the industrial production of fructooligosaccharides (FOS). However, it is still not possible to explain difference FOS based on variations observed synthesizing enzymes A. niger. In present study, a novel fructosyltransferase (FT-A) from niger TCCC41686 with high synthesis ability was characterized. The FT-A gene obtained and expressed Pichia pastoris. A homology model showed that changes residues identified outside conserved domains were found an...
Abstract Beryllium and its compounds are systemic toxicants that mainly accumulate in the lungs. As a regulator of gene expression, microRNAs (miRNAs) were involved some lung diseases. This study aimed to analyze levels inflammatory cytokine differential expressions miRNAs human bronchial epithelial cells (16HBE) induced by beryllium sulfate (BeSO 4 ) further explore biological functions differentially expressed miRNAs. The profile 16HBE was detected using high‐throughput sequencing between...
In this study, the complete mitochondrial genome (mitogenome) sequence of Chinese bahaba was determined by long PCR and primer walking methods. The is 16,500 bp in length contains 37 genes (13 protein-coding genes, 2 ribosomal RNA 22 transfer genes) as well a control region (CR) other bony fishes. Within CR, we identified extended termination-associated domain, central conserved block domains (CSB-D, CSB-E CSB-F) (CSB-1, CSB-2 CSB-3).
Beryllium sulfate (BeSO
Abstract Chieh-qua ( Benincasa hispida Cogn. var. How.) fruit development starts post pollination. With the continuous expansion of fruit, soluble solid content decreases. Because there are no reports on early this study compared transcriptomes at 0-, 3-, and 7 day pollination (dpp). 104,747 unigenes were assembled from clean reads using six public databases for similarity searching. Compared with those 0 dpp (C), differences in expression 12,982 6541 genes tissue 3 dpp, respectively. (B),...
Circular RNAs (circRNAs), a new type of non-coding RNA, have been demonstrated to play critical roles in the progression various malignant cancers. However, function circRNAs breast cancer is not clearly understood.qPCR was used evaluate gene expression. Function studies including MTT, transwell, wound healing and colony formation assay were performed circPTCD3 cancer. Luciferase RNA pull-down assays verify interaction between miR-198. The xenograft model established vivo.In present study,...
12-oxo-phytodienoic acid (OPDA) is a biosynthetic precursor of jasmonic and triggers multiple biological processes from plant development to stress responses. However, the OPDA signaling relevant regulatory networks were largely unknown in basal land plants. Using an integrated multi-omics technique, we investigated global features metabolites transcriptional profiles Antarctic moss (Pohlia nutans) response treatment. We detected 676 based on widely targeted metabolomics approach. A total 82...