Nicolas Porta
A5055658206- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Congenital Heart Disease Studies
- Neuroscience of respiration and sleep
- Pulmonary Hypertension Research and Treatments
- Birth, Development, and Health
- Infant Development and Preterm Care
- Neonatal Health and Biochemistry
- Pregnancy and preeclampsia studies
- Mechanical Circulatory Support Devices
- Neonatal and fetal brain pathology
- Intestinal Malrotation and Obstruction Disorders
- Respiratory Support and Mechanisms
- Palliative Care and End-of-Life Issues
- Congenital Anomalies and Fetal Surgery
- Infant Nutrition and Health
- Hydrogen's biological and therapeutic effects
- Cardiovascular Issues in Pregnancy
- Dialysis and Renal Disease Management
- Nitric Oxide and Endothelin Effects
- Chronic Kidney Disease and Diabetes
- Tracheal and airway disorders
- Lymphatic Disorders and Treatments
- Ethics and Legal Issues in Pediatric Healthcare
- Intestinal and Peritoneal Adhesions
Lurie Children's Hospital
2014-2025
Northwestern University
2014-2025
Women's Hospital
2021-2022
RELX Group (Netherlands)
2017
Northwestern Memorial Hospital
2002-2012
New York University Press
2011
Chitose Institute of Science and Technology
2011
University of Hertfordshire
2011
Cambridge University Press
2011
University of California, San Francisco
1997-2002
Inflammation has been associated with preterm delivery and adverse neonatal outcomes such as cerebral palsy chronic lung disease. However, no study to date simultaneously examined a wide range of inflammatory mediators their relationship gestational age. We sought describe the distribution immune biomarkers in cord blood across age investigate association between biomarker level patterns birth.As part large-scale molecular epidemiological birth conducted at Boston Medical Center, this...
Prostacyclin is a pulmonary vasodilator and produced by prostacyclin synthase stimulates adenylate cyclase (AC) via the receptor (IP) to produce cAMP. Forskolin direct stimulant of AC. Phosphodiesterase 3 hydrolyzes cAMP inhibited milrinone. Objective: To characterize prostacyclin-AC-cAMP pathway in ovine ductal ligation model persistent hypertension newborn (PPHN). Setting: University-based laboratory animal facility. Subjects: Lambs delivered time-dated pregnant ewes. Interventions: Fifth...
The aim of this study is to characterize medical and surgical therapies short-term outcomes in infants with congenital diaphragmatic hernia (CDH).Retrospective analysis CDH admitted 27 children's hospitals submitting data Children's Hospital Neonatal Database (CHND) from 2010 2013, stratified by gestational age, birth weight, survival.A total 572 were identified, 508 (89%) born ≥ 34 weeks' gestation 2 kg. More mature had higher APGAR scores, shorter duration mechanical ventilation, more...
The development of pulmonary hypertension (PH) is a serious complication bronchopulmonary dysplasia (BPD) among infants born at extremely low gestational ages. Bronchopulmonary dysplasia-associated PH characterized by persistent vasoconstriction, progressive right heart dysfunction, and an increased risk death. We have shown previously that certain placental vascular lesions are associated with BPD-associated PH. Further evaluation the villous morphometry these placentas warranted. Using...
<h3>Importance</h3> Understanding why and how extremely preterm infants die is important for practitioners caring these infants. <h3>Objective</h3> To examine risk factors, causes, timing, circumstances of death in a modern cohort <h3>Design, Setting, Participants</h3> A retrospective review enrolled the Preterm Erythropoietin Neuroprotection Trial between December 13, 2013, September 26, 2016, was conducted. total 941 born 24 0/7 27 6/7 weeks gestation at 19 US sites comprising 30 neonatal...
Oligohydramnios (OH) retards fetal lung growth by producing less distension than normal. To examine effects of decreased on development, we produced OH in rats puncture uterus and membranes at 16 days gestation; fetuses were delivered 21 or 22 gestation. Controls position-matched littermates the opposite uterine horn. lungs had lower weights DNA, protein, water, but no differences saturated phosphatidylcholine, surfactant proteins (SP)-A -B, mRNA for SP-A, -C, -D. evaluate epithelial...