A. Merighi

ORCID: 0000-0002-8642-9072
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About
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Research Areas
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Esophageal and GI Pathology
  • Inflammatory Bowel Disease
  • Gastric Cancer Management and Outcomes
  • Colorectal Cancer Screening and Detection
  • Liver Disease and Transplantation
  • Microscopic Colitis
  • Liver Disease Diagnosis and Treatment
  • Gallbladder and Bile Duct Disorders
  • Organ Transplantation Techniques and Outcomes
  • Helicobacter pylori-related gastroenterology studies
  • Eosinophilic Esophagitis
  • Gastrointestinal disorders and treatments
  • Pancreatic and Hepatic Oncology Research
  • Gastroesophageal reflux and treatments
  • Medical Device Sterilization and Disinfection
  • Pediatric Hepatobiliary Diseases and Treatments
  • Clinical Nutrition and Gastroenterology
  • Nutrition and Health in Aging
  • Autoimmune and Inflammatory Disorders
  • Mycobacterium research and diagnosis
  • Healthcare Quality and Management
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Genetic factors in colorectal cancer
  • Colorectal Cancer Treatments and Studies

University of Ferrara
2020-2025

Arcispedale Sant'Anna
1996-2023

University of Bologna
2023

Istituto Oncologico Veneto
2023

Istituti di Ricovero e Cura a Carattere Scientifico
2023

University of Modena and Reggio Emilia
1996-2020

Azienda Ospedaliero-Universitaria di Modena
2000-2018

Shiga University of Medical Science
2016

Juntendo University
2016

Ospedale Sant'Anna
1992-1996

Abstract Colorectal mucosa is targeted by toxic agents, which can initiate or promote colon cancer. The mechanism of damage might be a focal irritation with loss normal epithelial cell barrier function. Genetic alterations in tumors may also affect host inflammatory response. aim this study was to define the extent inflammation colorectal mucosa, along carcinogenesis, and microsatellite stable unstable carcinomas. We collected 103 samples from 65 patients (35 cancer adenoma, 8 bowel...

10.1158/1055-9965.epi-08-0224 article EN Cancer Epidemiology Biomarkers & Prevention 2008-09-01

Anticoagulants are commonly indicated in cirrhotic patients due to high rate of (pro)thrombotic conditions. Low molecular weight heparin (LMWH) is safe with esophageal varices. However, the safety LMWH unknown undergoing prophylactic endoscopic variceal ligation (EVL). To define 4-week risk bleeding and death after EVL continuously treated LMWH.All EVLs performed at a tertiary Italian Center from 2009 2016 were retrospectively reviewed. Patients classified as on-LMWH; remaining no-LMWH....

10.1111/liv.13728 article EN Liver International 2018-02-22

Despite the increasing use of early esophagogastroduodenoscopy, prognostic evaluation and triage patients who have ingested caustic material is challenging. We evaluated usefulness selected clinical endoscopic parameters in predicting risk death after ingestion substances.Clinical were obtained from records all admitted to our endoscopy unit because between 1 March 1982 30 June 1999. Parameters significantly associated with by univariate analysis entered into a multivariate logistic model....

10.1055/s-2002-23633 article EN Endoscopy 2002-04-01

CASE REPORT Biliary stents migration rate is about 5%–10%, in particular the of plastic biliary stent reported to be up 13.5%. Of latter, proximal less frequent than distal migration, but, when it occurs, often symptomatic and requires endoscopic retrieval.1,2 The risk factors associated with are categorized into patient-related stent-related factors. linked patient's characteristics dilation common bile duct (CBD) (>1 cm), presence benign strictures, if these strictures has been previously...

10.14309/crj.0000000000001565 article EN cc-by-nc-nd ACG Case Reports Journal 2025-01-01

Introduction. Colorectal non-polypoid lesions (NPLs) are flat, hard-to-detect and mainly right-sided lesions. We aimed to assess the prevalence endoscopic features of NPLs in a large cohort screening patients Northern Italy. Methods. FIT-positive subjects between 50 69 years old who had undergone at least colonoscopy from March 2005 December 2017 Endoscopy Unit Ferrara were included. selected only non-diminutive (>5 mm) neoplastic polyps (i.e.: adenomas, serrated adenomas carcinomas)....

10.1159/000543307 article EN Digestive Diseases 2025-01-21

The most appropriate endo-therapeutic approach to biliary anastomotic strictures is yet be defined.To retrospectively report on the endo-therapy of duct-to-duct during 2013 in Italy.Data were collected from 16 Endoscopy Units at Italian Liver Transplantation Centers (BASALT study group).Complete and follow-up data are available for 181 patients: 101 treated with plastic multistenting, 26 fully covered self-expandable metal stenting 54 single stenting. Radiological success was achieved 145...

10.1111/liv.14010 article EN Liver International 2018-11-30

When treating potentially resectable pancreatic adenocarcinoma, therapeutic decisions are left to the sensibility of clinicians who, faced with a decision that post hoc can be proven wrong, may feel sense regret they want avoid. A regret-based model was applied evaluate attitudes toward neoadjuvant therapy versus upfront surgery for adenocarcinoma.Three clinical scenarios describing high-, intermediate-, and low-risk disease-specific mortality after were presented 60 respondents (20...

10.1016/j.surg.2023.01.016 article EN cc-by Surgery 2023-03-15

The delay between onset of symptoms and coronary care unit admission is decisive in the outcome patients with acute myocardial infarction.To evaluate influence factors that affect infarction treatment.Multicenter case-control study conducted by 118 units Italy. median mean times cases controls were compared for decision time, home-to-hospital in-hospital several potential risk on was evaluated comparison admitted more than 6 hours after those within onset.Among 5301 infarction, 590 who came...

10.1001/archinte.155.14.1481 article EN Archives of Internal Medicine 1995-07-24

Gastritis is an inflammation of the gastric mucosa. In this study, we investigated efficacy a medical device, Esoxx®, based on hyaluronic acid and chondroitin sulfate gastritis-related upper abdominal pain/discomfort endoscopic features. Fifty patients, affected by gastritis, were randomised to receive device or placebo. The primary endpoint was associated with gastritis measured Visual Analogue Scale (VAS). secondary endpoints mucosal erosions, blood oozing, hyperemia (redness)/edema, as...

10.1007/s13346-018-0531-7 article EN cc-by Drug Delivery and Translational Research 2018-05-23

Background: Helicobacter pylori is strongly associated with peptic ulcer: H. eradication markedly decreases the recurrence rate of duodenal and gastric ulcer, but optimum length antibiotic therapy in still unclear. Aim: To verify effectiveness side‐effect profile an eradicating regimen consisting omeprazole 20 mg daily for 4 weeks and, during first week, combination antimicrobial treatment tinidazole 500 b.d. plus clarithromycin 250 patients active ulcer. Methods: One hundred ninety‐six...

10.1046/j.1365-2036.1996.721101000.x article EN Alimentary Pharmacology & Therapeutics 1996-02-01

A novel medical device based on hyaluronic acid, chondroitin sulphate plus aluminum hydroxide (GERDOFF®, melt-in-mouth tablets) showed efficacy in reducing GER-related symptoms. This exploratory, open-label study evaluated symptomatic effects of a 14-day treatment with GERDOFF® GERD patients.GERD Impact Scale (GIS) questionnaire was filled at baseline visit, after 7 and 14 days treatment; patients' Global Satisfaction the final visit. Primary endpoint reduction heartburn episodes per week;...

10.5152/tjg.2020.19327 article EN The Turkish Journal of Gastroenterology 2020-05-03
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