A5021970759- Functional Brain Connectivity Studies
- Stress Responses and Cortisol
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mental Health Research Topics
- Child and Adolescent Psychosocial and Emotional Development
- Psychosomatic Disorders and Their Treatments
- Neural and Behavioral Psychology Studies
- Tryptophan and brain disorders
- Heart Rate Variability and Autonomic Control
- Child Abuse and Trauma
- Neuroendocrine regulation and behavior
- Substance Abuse Treatment and Outcomes
- Alcoholism and Thiamine Deficiency
- Posttraumatic Stress Disorder Research
- Action Observation and Synchronization
- Neurological and metabolic disorders
- Advanced Neuroimaging Techniques and Applications
- Acupuncture Treatment Research Studies
- Birth, Development, and Health
- Optimism, Hope, and Well-being
- Sleep and Wakefulness Research
- Health and Wellbeing Research
- Visual perception and processing mechanisms
- Bipolar Disorder and Treatment
- Infrared Thermography in Medicine
MSH Medical School Hamburg – University of Applied Sciences and Medical University
2018-2025
Humboldt-Universität zu Berlin
2024
Technische Universität Dresden
2010-2020
Carl von Ossietzky Universität Oldenburg
2010
Acute psychosocial stress in humans triggers the release of glucocorticoids (GCs) and influences performance declarative working memory (WM) tasks. These systems rely on hippocampus prefrontal cortex (PFC), where GC-binding receptors are present. Previous studies revealed contradictory results regarding effects acute WM-related brain activity. We combined functional magnetic resonance imaging with a standardized protocol to investigate mental activity during encoding, maintenance, retrieval...
Abstract Background Generalized anxiety disorder ( GAD ) is difficult to recognize and hard separate from major depression MD in clinical settings. Biomarkers might support diagnostic decisions. This study used machine learning on multimodal biobehavioral data a sample of , healthy subjects differentiate with (case‐classification) (disorder‐classification). Methods Subjects n = 19), without 14), comparison 24) were included. The was matched regarding age, sex, handedness education free...
Specific phobia (SP) is a prevalent mental disorder. Exposure-based treatments are the most effective therapy. Surprisingly, little known about intrinsic functional connectivity of SP and its modification by treatment, possibly due to strong focus on presumed fear network. Hypothesis-driven priori selection brain regions does not allow full extent potential changes in modulating effects therapy be captured. Therefore, we use magnetic resonance imaging (fMRI) combination with hypothesis-free,...
Specific phobia (SPH) is a prevalent anxiety disorder and may involve advanced biological aging. However, brain age research in psychiatry has primarily examined mood psychotic disorders. This mega-analysis investigated aging SPH participants within the ENIGMA-Anxiety Working Group. 3D s tructural MRI scans from 17 international samples (600 individuals, of whom 504 formally diagnosed 96 questionnaire-based cases; 1,134 controls; range: 22-75 years) were processed with FreeSurfer. Brain was...
Aims: To investigate the relation between acute stress exposure, alcohol consumption, and corti-sol levels among individuals with varying statuses of use disorder (AUD) family histories AUD.Design: We conducted a systematic search for primary studies registered in PubMed/Medline, Web Science, PsycInfo databases up to July 31, 2023, providing data on volume consumed millilitre after compared control procedures, or effect without simultaneous minimal (CMin indicating cortisol recovery)...
Drug cue reactivity (DCR) is the most widely used fMRI paradigm for studying substance use disorders (SUDs), yet its link to behaviour remains inconsistent due methodological and clinical heterogeneity.In this systematic review activation likelihood estimation (ALE) meta-analysis of 92 studies, we examined how design-related factors (fMRI design, control condition valence, stimulus matching action/tool-related content) (treatment compliance, drug severity) influence neural DCR. In addition...
It has been repeatedly shown that functional magnetic resonance imaging (fMRI) triggers distress and neuroendocrine response systems. Prior studies have revealed sympathetic arousal increases, particularly at the beginning of examination. Against this background it appears likely those stress reactions during scanning procedure may influence task performance neural correlates. However, question how elicited by itself act as a potential confounder fMRI data remains unresolved today....
Abstract Background Excessive alcohol consumption and use disorders (AUD) are among the leading preventable causes of premature morbidity mortality considered a major public health concern. In order to reduce individual societal burden excessive use, it is crucial identify high-risk individuals at earlier stages provide effective interventions prevent further progression. Stressful experiences important risk factors for AUDs. However, underlying biological psychological mechanisms still...
Nearly all functional magnetic resonance imaging (fMRI) studies are conducted in the supine body posture, which has been discussed as a potential confounder of such examinations. The literature suggests that cognitive functions, problem solving or perception, differ between and upright postures. However, effect posture on many functions is still unknown. Therefore, aim present study was to investigate effects (supine vs. sitting) one most frequently used paradigms sciences: N-back working...
Background: Substance use disorders (SUD) belong to the most frequent behavioural consequences of childhood abuse and neglect (CAN). If parents are concerned, SUD also an important risk factor for CAN. The relationship between CAN remains poorly understood. There is a need adequate treatments patients suffering from CAN, as well approaches prevent by with SUD. Objective: To describe aims structure German research network on relationships (CANSAS network). Method: Descriptive overview aims,...
Abstract Childhood maltreatment (CM) is a strong risk factor for alcohol dependence (AD) and associated with more severe course of the disease. Alterations hypothalamic‐pituitary‐adrenal (HPA) axis may play an important role in this relationship. The aim present study was to systematically investigate potential alterations HPA functioning AD diagnosis CM. Four groups were recruited: patients (n = 29; 10♀) without 33; 8♀) CM healthy controls 30; 20♀) 38; 15♀) Cumulative cortisol secretion...