A5015809298- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Maternal and fetal healthcare
- Maternal Mental Health During Pregnancy and Postpartum
- Neonatal Respiratory Health Research
- Maternal and Perinatal Health Interventions
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive System and Pregnancy
- Pregnancy and Medication Impact
- Preterm Birth and Chorioamnionitis
- Metabolomics and Mass Spectrometry Studies
- Breastfeeding Practices and Influences
- Vitamin D Research Studies
- Obesity, Physical Activity, Diet
- Child Nutrition and Feeding Issues
- Pregnancy-related medical research
- Neonatal and fetal brain pathology
- Infant Development and Preterm Care
- Iron Metabolism and Disorders
- Global Maternal and Child Health
- Prenatal Substance Exposure Effects
- Ectopic Pregnancy Diagnosis and Management
- Cardiovascular Issues in Pregnancy
- Child and Adolescent Health
University of Liverpool
2017-2025
Health & Life (Taiwan)
2018-2024
Pennsylvania State University
2023
Maine Farmland Trust
2022
Norwegian Womens Public Health Association
2022
Merseytravel
2022
University of Ulster
2022
University College Cork
2012-2021
Liverpool Women's Hospital
2019-2021
Imperial College Healthcare NHS Trust
2021
Most societies believe that a mother's psychological state can influence her unborn baby. Severe adverse life events during pregnancy have been consistently associated with an elevated risk of low birth weight and prematurity. Such the first trimester also congenital malformations.To assess effect in offspring antenatal maternal exposure to objective measure stress on neurodevelopment, specifically schizophrenia. We hypothesized strongest relationship would be exposures...
Recent decades have witnessed an increase in mean maternal age at childbirth most high-resourced countries. Advanced has been associated with several adverse and perinatal outcomes. Although there are many studies on this topic, data from large contemporary population-based cohorts that controls for demographic variables known to influence outcomes is limited.We performed a cohort study using all singleton births 2004-2008 the North Western Perinatal Survey based The University of...
Background— Hypertensive disorders of pregnancy are a major contributor to death and disability for pregnant women their infants. The diagnosis preeclampsia by using blood pressure proteinuria is limited use because they tertiary, downstream features the disease. Placental growth factor (PlGF) an angiogenic factor, secondary marker associated placental dysfunction in preeclampsia, with known low plasma concentrations Methods Results— In prospective multicenter study, we studied diagnostic...
<b>Objectives</b> To develop a predictive model for pre-eclampsia based on clinical risk factors nulliparous women and to identify subgroup at increased risk, in whom specialist referral might be indicated. <b>Design</b> Prospective multicentre cohort. <b>Setting</b> Five centres Auckland, New Zealand; Adelaide, Australia; Manchester London, United Kingdom; Cork, Republic of Ireland. <b>Participants</b> 3572 “healthy” with singleton pregnancy from large international study; data outcome were...
Preeclampsia is a pregnancy-specific syndrome that causes substantial maternal and fetal morbidity mortality. The etiology incompletely understood, there no clinically useful screening test. Current metabolomic technologies have allowed the establishment of metabolic signatures preeclampsia in early pregnancy. Here, 2-phase discovery/validation profiling study was performed. In discovery phase, nested case-control designed, using samples obtained at 15±1 weeks’ gestation from 60 women who...
More than half of all cases preeclampsia occur in healthy first-time pregnant women. Our aim was to develop a method predict those at risk by combining clinical factors and measurements biomarkers women recruited the Screening for Pregnancy Endpoints (SCOPE) study low-risk nulliparous Forty-seven identified on basis (1) association with preeclampsia, (2) biological role placentation, or (3) cellular mechanisms involved pathogenesis were measured plasma sampled 14 16 weeks’ gestation from...
BackgroundSevere early-onset fetal growth restriction can lead to a range of adverse outcomes including or neonatal death, neurodisability, and lifelong risks the health affected child. Sildenafil, phosphodiesterase type 5 inhibitor, potentiates actions nitric oxide, which leads vasodilatation uterine vessels might improve in utero.MethodsWe did this superiority, placebo-controlled randomised trial 19 medicine units UK. We used random computer allocation (1:1) assign women with singleton...
The study of metabolites (metabolomics) is increasingly being applied to investigate microbial, plant, environmental and mammalian systems. One the limiting factors that chemically identifying from mass spectrometric signals present in complex datasets.Three workflows have been developed allow for rapid, automated high-throughput annotation putative metabolite identification electrospray LC-MS-derived metabolomic datasets. collection are defined as PUTMEDID_LCMS perform feature annotation,...
The healthcare sector is a highly regulated environment that subject to numerous constraints. Standards around medical protocol, device certification, and data protection ensure the wellbeing privacy of patients protected during all encounters with system. However, gap has opened up between need meet these constraints, improve performance, also deliver good patient experience. For example, protocol for hypertension pregnancy establishes set clinically validated treatment guidelines, but does...
Objectives To investigate the association between hyperemesis gravidarum and altered cognitive, behavioural emotional well-being in pregnancy. Methods The study cohort consisted of 3423 nulliparous women recruited Screening for Pregnancy Endpoints (SCOPE) performed Auckland, New Zealand; Adelaide, Australia; Cork, Ireland; Manchester London, United Kingdom November 2004 August 2008. Women were interviewed at 15±1 weeks' gestation 20±1weeks' gestation. with a diagnosis (HG) compared who did...