A5101926681- Health disparities and outcomes
- Frailty in Older Adults
- Nutrition and Health in Aging
- Health Systems, Economic Evaluations, Quality of Life
- Health and Well-being Studies
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiovascular Health and Risk Factors
- Blood Pressure and Hypertension Studies
- Dementia and Cognitive Impairment Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Global Health Care Issues
- Nutritional Studies and Diet
- Cardiovascular Health and Disease Prevention
- Folate and B Vitamins Research
- Chronic Disease Management Strategies
- Health and Wellbeing Research
- Stroke Rehabilitation and Recovery
- Acute Myocardial Infarction Research
- Migration, Aging, and Tourism Studies
- Lipoproteins and Cardiovascular Health
- Cardiac Health and Mental Health
- Retirement, Disability, and Employment
- Cardiac Valve Diseases and Treatments
- Medical Research and Treatments
Lanzhou University
2025
First Hospital of Lanzhou University
2025
Gansu Provincial Maternal and Child Health Hospital
2025
Capital Medical University
2015-2024
Beijing Geriatric Hospital
2002-2024
National Clinical Research Center for Digestive Diseases
2018-2024
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2024
Peking University
2022-2024
Beijing Anzhen Hospital
2019-2023
Capital University
2004-2022
Social frailty is related to adverse health-related outcomes. However, the measurement thereof controversial and research into relationship between social physical functioning remains limited. This study aimed determine status via developing a simple self-reported screening tool, termed HALFT scale, examine association functioning, cognition, depression, mortality among community-dwelling older adults. Prospective cohort study. Community. 1697 adults aged ≥60 years from Beijing Longitudinal...
Frailty in older adults predicts dependence and mortality is a major challenge for healthcare systems countries with rapidly aging populations. Little known about frailty China. We investigated the prevalence associated risk factors of China.Cross-sectional.Data were obtained from China Comprehensive Geriatric Assessment Study, conducted 2011-12, which was first uniform comprehensive assessment system adopted China.Older 7 cities selected based on well-established cluster, stratification,...
Falls are well known to be associated with adverse health outcomes, especially when complicated by fracture. more common in people who frail and readily related several items the frailty phenotype. Less is about relationship between falls defined as deficit accumulation. Our objective was investigate falls, fractures, based on
Physical frailty, characterized by reduced physiologic complexity and ability to cope with stressors, is closely associated cognitive impairment, which increases the risk of poor clinical outcomes. To better capture association between frailty a new construct, has been proposed. Cognitive condition simultaneous presence physical impairment. There little evidence on relationship cognition, as well in Chinese older adults. We aimed elucidate whether impairment an population. Data were obtained...
Objectives Intrinsic capacity (IC) was proposed by the WHO as a new concept for capturing an individual’s functional capacities across their lifetime. We aimed to investigate prevalence and factors associated with IC decline examine associations between adverse outcomes among community-dwelling older adults in China. Design A cross-sectional study. Setting Community, Participants Data were derived from China Comprehensive Geriatric Assessment Study, population-based nationally representative...
Objective: Cognitive frailty (CF) refers to the co-occurrence of physical and cognitive impairment in persons without dementia. We aimed explore prevalence associated factors CF China. Method: Data were obtained from China Comprehensive Geriatric Assessment Study (CCGAS). A total 5708 community-dwelling older adults dementia included. was assessed using Mini-Mental State Examination for evaluation status Assessment-Frailty Index frailty. Participants with both classified as having CF....
Patients with atrial fibrillation (AF) and left (LA) enlargement may develop functional, normal leaflet motion mitral regurgitation (MR) without ventricular (LV) remodeling. Mitral annular dynamics LV mechanics are important for preserving valve function. The aim of this study was to assess the in patients AF functional MR.Twenty-one moderate or more MR (AFMR+ group), 46 matched no mild (AFMR- 19 were retrospectively studied. quantitatively assessed using three-dimensional echocardiography....
Background Cognitive impairment may increase the risk of all-cause and cardiovascular disease ( CVD ) mortality. This study examined association between cognitive function mortality among elderly in Beijing, China. Methods Results A total 1996 participants aged ≥55 years at baseline were enrolled from BLSA (Beijing Longitudinal Study Aging). was assessed using Mini-Mental State Examination MMSE ), categorized as: <18, 18 to 23, 24 27, 28 30. Cox proportional hazard models used estimate...
Abstract Background Frailty in individuals can be operationalized as the accumulation of health deficits, for which several trends have been observed Western countries. Less is known about deficit China, country with world's largest number older adults. Methods This study analyzed data from Beijing Longitudinal Study Aging, to evaluate relationship between age and men women impact frailty on mortality. Community dwelling people aged 55+ years at baseline (n = 3275) were followed every two...
Background: all cardiometabolic disorders become more common with age. Frailty and increased vulnerability to adverse outcomes are also aging. Even so, how commonly elderly people who affected by frail remains unclear. Objectives: (i) evaluate the prevalence of in relation frailty. (ii) To estimate which extent diseases, when compared frailty, affects mortality. Methods: this is a secondary analysis Beijing Longitudinal Study Ageing, population-based representative cohort study (n = 3,257)...
Hypertension and frailty are associated often coexist in older adults. Few studies have examined the association between hypertension Chinese population. We explored prevalence of factors with as well whether could identify patients at risk adverse outcomes among adults hypertension. Data were from Beijing Longitudinal Study Aging. A total 1111 hypertensive participants aged ≥60 years old who completed comprehensive geriatrics assessment included. All followed up for 8 years. The number...
Multimorbidity is common in older hospitalized adults. To date, however, few studies have addressed multimorbidity the population of Chinese inpatients. We aimed to investigate rate and associated risk factors adult inpatients China.
On average, as people age, they accumulate more health deficits and have an increased risk of death. The deficit accumulation-based frailty index (FI) can quantify its outcomes in aging. Previous studies suggested that women show higher FI values than men the highest score (the "limit to frailty") occurs at a value ~ 0.7. Even so, gender differences limit not been reported.Data for this analysis were obtained from Beijing Longitudinal Study Aging involved 3,257 community-dwelling Chinese...
Objective Time-dependent covariates are generally available as longitudinal data were collected periodically in the cohort study. To examine whether time-dependent triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio could predict future risk of type 2 diabetes mellitus (T2DM) and assess its potential impact on T2DM incidence. Research design methods This study enrolled 1460 participants without aged 55 or above 1992 Beijing Longitudinal Study Aging during 25 years. The...
Background: We assessed the effects of smoking and cessation on life expectancy active among persons aged 55 years or older in Beijing.Methods: This study included 1593 men 1664 women who participated Beijing Longitudinal Study Aging, which commenced 1992 had 4 survey waves up to year 2000. An abridged table was used estimate expectancy, age-specific mortality disability rates were adjusted by using a discrete-time hazard model control confounders.Results: The mean ages (SD) for 70.1 (9.25)...
Objectives To evaluate transitions in health status and risk of death older adults relation to baseline deficits protective factors. Design Prospective cohort study with reassessments at 5, 8, 15 years. Setting Secondary analysis data from the Beijing Longitudinal Study on Aging. Participants Urban rural community‐dwelling people aged 55 (n = 3,275), followed 1992 2007, during which time 51% died. Measurements Health was quantified using deficit accumulation–based frailty index (FI),...
We assessed the effect of asymptomatic carotid atherosclerosis (CAS) on development cardiovascular diseases (CVDs) in a community-based population aged ≥55 years China. A total 1376 residents underwent CAS assessment by ultrasonography July 2009. New CVD events, including stroke and coronary heart were collected at follow-up survey end 2014. After adjusting for baseline demographic characteristics traditional risk factors, patients with minimal (mean common artery intima–media thickness...