A5100725711- Infectious Diseases and Tuberculosis
- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Orthopedic Infections and Treatments
- Bacterial Identification and Susceptibility Testing
- Tuberculosis Research and Epidemiology
- Infective Endocarditis Diagnosis and Management
- Streptococcal Infections and Treatments
- Pneumonia and Respiratory Infections
- Glaucoma and retinal disorders
- Clostridium difficile and Clostridium perfringens research
- Bacterial biofilms and quorum sensing
- Bacterial Infections and Vaccines
- Central Venous Catheters and Hemodialysis
- Urinary Tract Infections Management
- Nosocomial Infections in ICU
- Mycobacterium research and diagnosis
- Diagnosis and treatment of tuberculosis
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Retinal Diseases and Treatments
- Amoebic Infections and Treatments
- Retinal and Macular Surgery
- Pneumocystis jirovecii pneumonia detection and treatment
- Orthodontics and Dentofacial Orthopedics
Kyung Hee University Dental Hospital
2014-2025
Kyung Hee University
2014-2024
Kyung Hee University Medical Center
2014-2022
Seoul National University Hospital
2021
Korea University
2020
Asan Medical Center
2009-2016
University of Ulsan
2009-2016
Ulsan College
2009-2016
Seoul National University
1989-2016
Gyeongsang National University Hospital
2016
Rationale: The role of viruses in pneumonia adults and the impact viral infection on mortality have not been elucidated. Previous studies significant limitations that they relied predominantly upper respiratory specimens.Objectives: To investigate adult patients with requiring intensive care unit (ICU) admission.Methods: A retrospective analysis a prospective cohort was conducted 28-bed medical ICU. Patients severe community-acquired (CAP) or healthcare-associated (HCAP) were included...
Background. The optimal duration of antibiotic treatment for hematogenous vertebral osteomyelitis (HVO) should be based on the patient's risk recurrence, but it is not well established. Methods. A retrospective review was conducted to evaluate in patients with HVO at low and high recurrence. Patients least 1 independent baseline factor determined by multivariable analysis, were considered as those no risk. Results. total 314 microbiologically diagnosed evaluable In methicillin-resistant...
ABSTRACT Practice guidelines recommend at least 14 days of antibiotic therapy for uncomplicated Staphylococcus aureus bacteremia (SAB). However, these recommendations have not been formally evaluated in clinical studies. To evaluate the duration SAB, we analyzed data from our prospective cohort patients with SAB. A observational study was performed SAB a tertiary-care hospital Korea between August 2008 and September 2010. All adult were prospectively enrolled observed over 12-week period....
Persistent Staphylococcus aureus bacteremia (SAB) that fails to respond appropriate antibiotic therapy is associated with poor outcomes. Comprehensive prospective studies on risk factors and outcomes of persistent are limited. We investigated encompassing clinical, pharmacokinetic, microbiologic, genotypic characteristics using a case-control study nested in cohort patients SAB at tertiary-care hospital from August 2008 through September 2010. compared the clinical characteristics,...
Pseudomonas aeruginosa has gained an increasing amount of attention in the treatment patients with pneumonia. However, benefit empirical combination therapy for pneumonia remains unclear. We evaluated effects adequate and multidrug-resistance bacteremic on mortality.A retrospective cohort study was performed at 2,700-bed tertiary care university hospital. reviewed medical records between January 1997 February 2011. Patients who received either inappropriate or appropriate were compared by...
COVID-19의 장기화가 정신 건강에 미치는 영향을 연구하기 위해, 본 연구는 2020년 5월 8일부터 13일까지 1,000명의 국내 참가자들을 대상으로 외상성 고통, 예방 행동, 우울, 불안, 자살 위험성 등을 조사하였다. 전후의 심리적 비교하기 위해 COVID-19 이전 기간(2017년 10월부터 2018년 3월까지) 동안 수집된 257명의 참가자 자료를 활용하였다. 추가적으로 상황에서 실직이나 가계수입 감소와 같은 경제적 위험 요인 및 일상 활동의 유지와 보호 요인들을 탐색하였다. 27.3%의 참가자들이 경도 수준 이상의 고통을, 34.2%의 우울 증상을, 28.8%의 불안 증상을 COVID- 19기간 나타냈으며, 23.6%의 집단으로 분류되었다. 여성과 20대가 남성 다른 연령대의 참가자에 비해 높은 경향성을 보였다. 연구결과를 국가의 연구결과와 비교하였을 때, 참가자들은 고통 증상의수준은 상대적으로 낮게 나타났으며 수준의 나타냈다. 코로나로 인한 악영향은 수입의...
Of 522 patients with Propionibacterium acnes bacteremia (PAB), 18 (3.5%) had clinically significant PAB. these patients, 10 (55.6%) hospital-acquired and 6 (33.3%) undergone invasive procedures before development of One patient a ventricular septal defect presented infective endocarditis. After the exclusion 1 whose outcome was not available, overall mortality rate 5.9% (1/17).
Abstract Objectives Community-associated MRSA (CA-MRSA) has emerged in the community and recently been spreading healthcare settings. The objectives of this study were to evaluate clinical outcomes bacterial virulence factors Korean CA-MRSA (ST72-SCCmecIV) strain, which causes bloodstream infections. Methods All adult patients with bacteraemia prospectively enrolled. Clinical outcomes, microbiological characteristics 40 evaluated. Results Of 352 typed isolates, 342 isolates (97.2%) belonged...
ABSTRACT A differential time to positivity (DTP) of ≥120 min is useful for diagnosing catheter-related bacteremia, but data on candidemia (CRC) in this way are limited. We wished evaluate the usefulness DTP CRC. All adult patients who had same Candida species isolated from blood cultures drawn simultaneously a central venous catheter (CVC) and peripheral vein were included at tertiary care hospital over an 18-month period. total 105 with positive simultaneous CVC our study. Sixty-one (58%)...
Patients with hematogenous vertebral osteomyelitis (HVO) occasionally require instrumentation for spinal stabilization. However, placing in the setting of infection raises concerns about recurrent due to bacteria adhering foreign material. In this study, we evaluated therapeutic outcomes patients HVO who underwent instrumented surgery.We conducted a retrospective chart review adult microbiologically diagnosed surgical intervention 5 tertiary care hospitals over an 8-year period.A total 153...
We describe the genetic and microbiological characteristics of methicillin-resistant Staphylococcus aureus (MRSA) bloodstream isolates with agr dysfunction from a tertiary-care hospital in Korea. Of these, ST5-SCCmec type II-agr group II MRSA isolates, which are known to be prevalent hospital-acquired infections Korea, were most abundant, because clonal spread specific agr-defective lineage. This finding suggests that loss function may confer potential advantage setting. Clonal defective-agr...
Abstract Spinal implant infection is a rare but significant complication of spinal fusion surgery, and the most common pathogen Staphylococcus aureus . It difficult to treat due this pathogen's biofilm-forming ability antibiotic resistance. We evaluated therapeutic outcome treatments for S infections. retrospectively reviewed all patients with infections at 11 tertiary-care hospitals over 9-year period. Parameters predictive treatment failure recurrence were analyzed by Cox regression. Of...
Background Empiric antibiotic therapy for suspected hematogenous vertebral osteomyelitis (HVO) should be initiated immediately in seriously ill patients and may required those with negative microbiological results. The aim of this study was to inform the appropriate selection empiric regimens treatment HVO by analyzing antimicrobial susceptibility isolated bacteria from microbiologically proven HVO. Method We conducted a retrospective chart review adult five tertiary-care hospitals over...
Multidrug-resistant (MDR) bacteria have become a severe problem for public health. Developing new antibiotics MDR is difficult, from inception to the clinically approved stage. Here, we used approach, modification of an antibiotic, ciprofloxacin (CFX), with triphenylphosphonium (TPP, PPh3) moiety via ester- (CFX-ester-PPh3) and amide-coupling (CFX-amide-PPh3) target bacterial membranes. In this study, evaluated antibacterial activities CFX its derivatives against 16 species bacteria,...
Abstract Despite the improved outcomes in patients with hematological malignancies, infections caused by multidrug-resistant organisms (MDROs) pose a new threat to these patients. We retrospectively reviewed cancer and bacterial bloodstream (BSIs) at tertiary hospital between 2003 2022 assess impact of MDROs on outcomes. Among 328 BSIs, 81 (24.7%) were MDROs. MDRO rates increased from 10.3% (2003–2007) 39.7% (2018–2022) ( P < 0.001). The 30-day mortality rate was 25.0%, which...
<title>Abstract</title> Purpose The management of fracture-related infections (FRIs) is complex and requires collaboration among various specialists, including trauma orthopedic surgeons, infectious disease (ID) microbiologists. This study aimed to investigate the effects ID consultations on antibiotic treatment FRI outcomes. Methods We conducted a retrospective chart review data from adult patients with microbiologically diagnosed FRIs at tertiary care hospital. Results In total, 123 were...