Eun Ju Choo
A5034491396- Antimicrobial Resistance in Staphylococcus
- SARS-CoV-2 and COVID-19 Research
- Pneumonia and Respiratory Infections
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Respiratory viral infections research
- Influenza Virus Research Studies
- Infective Endocarditis Diagnosis and Management
- COVID-19 Clinical Research Studies
- Streptococcal Infections and Treatments
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Herpesvirus Infections and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Infection Control in Healthcare
- Orthopedic Infections and Treatments
- Diagnosis and treatment of tuberculosis
- Urinary Tract Infections Management
- Antibiotic Use and Resistance
- Viral gastroenteritis research and epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Bacterial Infections and Vaccines
- Fungal Infections and Studies
- Mycobacterium research and diagnosis
- Hepatitis Viruses Studies and Epidemiology
Bucheon University
2015-2025
Soonchunhyang University
2015-2025
Chung-Ang University
2025
Soonchunhyang University Hospital
2006-2017
San Francisco General Hospital
2016-2017
University of California, San Francisco
2016
University of Ulsan
2002-2009
Ulsan College
2003-2009
Asan Medical Center
2003-2007
There is limited information about the clinical course and viral load in asymptomatic patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).To quantitatively describe SARS-CoV-2 molecular shedding symptomatic patients.A retrospective evaluation was conducted for a cohort of 303 infection between March 6 26, 2020. Participants were isolated community treatment center Cheonan, Republic Korea.Epidemiologic, demographic, laboratory data collected analyzed. Attending...
Approximately 10 years after vaccination with the recombinant zoster vaccine (RZV), an interim analysis of this follow-up study ZOE-50/70 trials demonstrated that efficacy against herpes remained high. Moreover, safety profile clinically acceptable, suggesting clinical benefit RZV in ≥50-year-olds is sustained up to years.
Abstract Background The adjuvanted RSV prefusion F protein–based vaccine (RSVPreF3 OA) was efficacious against RSV-related lower respiratory tract disease (RSV-LRTD) in ≥60-years-olds over 1 season. We evaluated efficacy and safety of RSVPreF3 OA dose 2 doses given year apart RSV-LRTD seasons post–dose 1. Methods In this phase 3, blinded trial, ≥60-year-olds were randomized (1:1) to receive or placebo pre–season recipients re-randomized a second (RSV_revaccination group) (RSV_1dose 2;...
Abstract Background This ongoing follow-up study evaluated the persistence of efficacy and immune responses for 6 additional years in adults vaccinated with glycoprotein E (gE)-based adjuvanted recombinant zoster vaccine (RZV) at age ≥50 2 pivotal trials (ZOE-50 ZOE-70). The present interim analysis was performed after ≥2 (between 5.1 7.1 [mean] post-vaccination) includes partial data year (Y) 8 post-vaccination. Methods Annual assessments were against herpes (HZ) from Y6 post-vaccination...
Abstract Background Older adults with chronic cardiorespiratory or endocrine/metabolic conditions are at increased risk of respiratory syncytial virus (RSV)-related acute illness (RSV-ARI) and severe disease. In an ongoing, randomized, placebo-controlled, multicountry, phase 3 trial in ≥60-year-old participants, AS01E-adjuvanted RSV prefusion F protein-based vaccine (RSVPreF3 OA) was efficacious against RSV-related lower tract disease (RSV-LRTD), RSV-LRTD, RSV-ARI. We evaluated efficacy...
The isolation of carbapenem-resistant Klebsiella pneumoniae (CRKP) has been increasingly reported. However, no study analyzing potential risk factors for the acquisition CRKP published as now. We therefore performed a case-control to determine CRKP. was nosocomially isolated from 30 patients between January 1997 and August 2003. Control were randomly selected at ratio 4:1 same medical or surgical services which receiving care when occurred. Risk previous use carbapenem (adjusted odds [AOR],...
ABSTRACT Penicillin-binding protein 4 (PBP4), a nonessential, low-molecular-weight penicillin-binding of Staphylococcus aureus , has been implicated in low-level resistance to β-lactam antibiotics, although the mechanism is unknown. Mutations PBP4 and its promoter were identified laboratory-generated mutant strain, CRB, which expresses high-level β-lactams, including new-generation cephalosporins active against methicillin-resistant strains S. . These mutations did not appreciably alter...
Abstract Background Numerous vaccine strategies are being advanced to control SARS-CoV-2, the cause of COVID-19 pandemic. EuCorVac-19 (ECV19) is a recombinant protein nanoparticle that displays SARS-CoV-2 receptor-binding domain (RBD) on immunogenic nanoliposomes. Methods Initial study phase 2 randomized, observer-blind, placebo-controlled trial assess immunogenicity, safety, and tolerance ECV19 was carried out between July October 2021. Two hundred twenty-nine participants were enrolled at...
The Korean Society of Infectious Diseases has been regularly developing guidelines for adult immunization since 2007. In 2023, the following seven vaccines were revised: influenza, herpes zoster, pneumococcal, tetanus-diphtheria-pertussis (Tdap), human papillomavirus (HPV), meningococcal, and rabies vaccines. For influenza vaccine, a recommendation enhanced elderly was added. zoster recombinant vaccine pneumococcal current status 15-valent conjugate 20-valent PCV described. Tdap possibility...
The nephrotoxicity of colistin has been reported in the literature. A previous report shown that acute kidney injury (AKI) occurred after an average 13.5 days, but we have experienced AKI developed with administration earlier. We investigated clinical features patients who according to time development use. retrospectively collected data were admitted 4 hospitals between January 2007 and May 2009. This study included 119 had received intravenous for over 72 h. compared early group (AKI...
We investigated the prevalence of latent tuberculosis infection (LTBI) among health care workers (HCWs) and analyzed its risk factors in South Korea.A standard questionnaire regarding baseline demographics for LTBI was given to each participant tuberculin skin test (TST), QuantiFERON-TB GOLD In-Tube (QFT-GIT) assay, chest radiography were performed.A total 493 participants, 152 (30.8%) doctors 341 (69.2%) nurses enrolled eight tertiary referral hospitals. The mean age subjects 30.6 years...
Acinetobacter baumannii, an opportunistic nosocomial pathogen that can cause significant morbidity and mortality, has emerged as a worldwide problem. The aim of this study was to evaluate the risk factors for mortality in patients with A. baumannii bacteremia. We retrospectively evaluated 118 who had bacteremia between July 2003 December 2011. identify 30-day relevant factors. bacteremia-related rate 34.1%. Univariate analysis revealed included malignancy, longer hospital stay before...
•Multi-drug resistant organisms (MDRO) were isolated from 8.6% of COVID-19 pneumonia.•MDROs detected 28% (13/47) among patients with culture data.•Long-term care facility stay was a risk factor for isolation organisms.•Corticosteroids use in may increase the bacterial co-infection.•Strict infection prevention strategies be needed factors. ObjectivesSuperimposed multi-drug (MDROs) co-infection can associated worse outcomes severe coronavirus disease 2019 (COVID-19), even if these managed...
EuCorVac-19 (ECV-19), an adjuvanted liposome-displayed receptor binding domain (RBD) COVID-19 vaccine, previously reported interim Phase 2 trial results showing induction of neutralizing antibodies 3 weeks after prime-boost immunization. The objective this study was to determine the longer-term antibody response vaccine.To assess immunogenicity 6 and 12 months vaccination, participants in (NCT04783311) were excluded if they: 1) withdrew, 2) infection or additional 3) exhibited increasing...
The clinical significance and virulence potential of Enterococcus casseliflavus/flavescens gallinarum are still uncertain. We retrospectively analyzed 56 cases significant bacteremia caused by E. casseliflavus or gallinarum. Of these cases, 25 (44.6%) were associated with polymicrobial bacteremia, 43 (76.8%) entry via the biliary tract. Resistance to vancomycin was observed in 17 (30.4%) patients, this resistance significantly (adjusted odds ratio [AOR], 10.56; 95% confidence interval [CI],...
Objectives: We investigated the trends of nalidixic acid resistance in human non-typhoid Salmonella enterica a Korean population, and examined some possible mechanisms involved this resistance.
We estimated the nationwide burden of nosocomial S. aureus bloodstream infection (SA-BSI), a major cause infection, in South Korea. To evaluate incidence SA-BSI, cases SA-BSI were prospectively collected from 22 hospitals with over 500 beds 4?months. Data on patient-days obtained national health insurance database containing claims data for all healthcare facilities The additional cost was through matched case?control study. economic calculated sum medical costs, costs caregiving and loss...
Abstract Spinal implant infection is a rare but significant complication of spinal fusion surgery, and the most common pathogen Staphylococcus aureus . It difficult to treat due this pathogen's biofilm-forming ability antibiotic resistance. We evaluated therapeutic outcome treatments for S infections. retrospectively reviewed all patients with infections at 11 tertiary-care hospitals over 9-year period. Parameters predictive treatment failure recurrence were analyzed by Cox regression. Of...
In South Korea, the increasing incidence of herpes zoster (HZ) and aging population warrant consideration HZ vaccination for older adults. There is a need to understand vaccine-related preferences adults aged ≥50 years adult children (working or financially independent contributing healthcare decision-making their parents years). A discrete choice experiment was conducted elicit vaccine HZ-naïve general public (n = 500), current/former patients 150), 150). An online questionnaire...