A5103095697- Antibiotic Resistance in Bacteria
- Enterobacteriaceae and Cronobacter Research
- Bacterial biofilms and quorum sensing
- Bacterial Identification and Susceptibility Testing
- Pharmaceutical and Antibiotic Environmental Impacts
- Infective Endocarditis Diagnosis and Management
- Bacterial Infections and Vaccines
- Streptococcal Infections and Treatments
- Antimicrobial Resistance in Staphylococcus
- Metabolism and Genetic Disorders
- Pneumonia and Respiratory Infections
- Antibiotics Pharmacokinetics and Efficacy
- Mitochondrial Function and Pathology
- Vibrio bacteria research studies
- Disaster Response and Management
- COVID-19 Clinical Research Studies
- Disaster Management and Resilience
- Long-Term Effects of COVID-19
- Mycobacterium research and diagnosis
- Antibiotic Use and Resistance
- Data-Driven Disease Surveillance
- Respiratory viral infections research
- Amino Acid Enzymes and Metabolism
- Reproductive tract infections research
- Inflammatory mediators and NSAID effects
Tohoku Medical and Pharmaceutical University Hospital
2021-2025
Tohoku Medical and Pharmaceutical University
2022-2025
Hiratsuka City Hospital
2024
Tohoku University
2011-2020
International University of Health and Welfare
2017-2019
Nara Medical University
2016
Kawagoe Technical High School
2016
Tokushima University
2003
National Institutes of Health
1985
National Institute of Neurological Disorders and Stroke
1985
Acinetobacter baumannii presents a clinical challenge when it is non-susceptible to carbapenems. The prevalence of carbapenem-non-susceptible A. in Japan unclear, as previous studies have been limited scope. We investigated the spread and performed comparison with findings from overseas. A total 305 non-duplicate isolates spp. 176 medical facilities all geographical regions were tested for susceptibility antimicrobial agents by agar dilution method. Isolates MICs imipenem ≥4 mg/L underwent...
The prevalence of ESBL has been increasing worldwide. In this study, we investigated the molecular characteristics among clinical isolates Escherichia coli from a Japanese tertiary hospital. A total 71 consecutive and nonduplicate ESBL-positive E. collected at Tohoku University Hospital between January 2008 March 2011 were studied. antimicrobial susceptibility profile these strains was determined. PCR sequencing performed to identify genes for β-lactamase (bla(TEM), bla(SHV),...
Extended-spectrum β-lactamases (ESBLs) have become a problem among AmpC-producing Enterobacteriaceae and the emergence of concomitant quinolone resistance in β-lactamase-producing isolates poses global threat. In this study we investigated prevalence regional variation ESBLs Japanese clinical Citrobacter spp. analysed plasmid-mediated (PMQR) determinants ESBL-producing spp.A total 348 collected throughout Japan were studied. Screening boronic acid disc test performed to detect with...
Objective To survey the epidemiology of respiratory pathogens during coronavirus disease 2019 (COVID-19) pandemic using multiplex polymerase chain reaction (PCR). Methods Specimens were assayed nested PCR. Materials obtained from outpatients who presented with symptoms upper tract infection and asymptomatic had contact patients severe acute syndrome 2 (SARS-CoV-2) at Tohoku Medical Pharmaceutical University Hospital in Sendai, Japan, November 1, 2020, to May 31, 2023. The analysis included...
Background Coronavirus disease 2019 (COVID-19) is an ongoing global pandemic. Bacterial coinfections with COVID-19 occur in 3.5% of cases, a higher incidence severe cases. Although antibiotics have been prescribed to treat non-critically ill patients COVID-19, their effect on hospitalized remains uncertain. Methods We analyzed data from who were older than 18 years between January 1, 2020, and May 31, 2023. performed propensity score matching analysis, evaluating in-hospital mortality or...
The incidence of extended-spectrum β-lactamases (ESBLs) has been increasing worldwide, but screening criteria for detection ESBLs are not standardized AmpC-producing Enterobacteriaceae such as Enterobacter species. In this study, we investigated the prevalence and/or AmpC in Japanese clinical isolates spp. and association plasmid-mediated quinolone resistance (PMQR) determinants with ESBL producers. A total 364 collected throughout Japan between November 2009 January 2010 were studied....
ABSTRACT Acinetobacter baumannii is generally the most frequently isolated species. Sequence analysis techniques allow reliable identification of isolates at species level. Forty-eight clinical spp. were obtained from blood cultures Tohoku University Hospital. These identified level by partial sequencing RNA polymerase β-subunit ( rpoB ), 16S rRNA, and gyrB genes. Then further characterization was done using PCR for detection OXA-type β-lactamase gene clusters, metallo-β-lactamases, carO...
We describe 2 post-tsunami outbreaks of influenza A in evacuation centers Miyagi Prefecture, Japan, 2011. Although containment the outbreak was challenging settings, prompt implementation a systemic approach with bundle control measures important to outbreaks.
Streptococcus pneumoniae is one of the most common bacteria causing acute otitis media (AOM). In Japan, a 7-valent pneumococcal conjugate vaccine (PCV7) was introduced for voluntary vaccination children in 2010, and it became recommended April 2013. We surveyed serotypes antimicrobial susceptibility profile S. isolates obtained from middle ear fluid Japanese with AOM.Between September 2013, total 176 were aged 0-3 years AOM. Isolates collected various regions Japan. Minimum inhibitory...
Nontypeable Haemophilus influenzae is a particularly important cause of acute otitis media (AOM). There high prevalence β-lactamase-nonproducing ampicillin-resistant (BLNAR) strains in Japanese children, which associated with recurrent AOM and prolonged treatment. The aim this study was to investigate the antimicrobial susceptibility profile, mechanisms ampicillin resistance molecular epidemiology H. causing children.One hundred fifty-seven isolated from middle ear fluid pediatric patients...
Actinomycosis of the middle ear and mastoid is extremely rare. Here, we report a unique case actinomycosis caused by Actinomyces meyeri diagnosed 16S rRNA gene sequence analysis.
Campylobacter rectus is a member of the human oral flora and associated with periodontal disease. We report first case severe acute otitis media (AOM) due to C. in previous healthy 15-year-old boy, which was confirmed by 16S ribosomal RNA gene sequencing. possible causative pathogen AOM.
Tuberculosis was diagnosed in a person who had stayed shelter after the 2011 Great East Japan Earthquake. A contact investigation showed that prevalence of latent tuberculosis infection among other evacuees at 20%. Our report underscores importance prevention and control natural disasters.