A5091688912- Liver Disease Diagnosis and Treatment
- Fatty Acid Research and Health
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Nutritional Studies and Diet
- Birth, Development, and Health
- RNA modifications and cancer
- Muscle Physiology and Disorders
- Nutrition and Health in Aging
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Gut microbiota and health
- Phytochemicals and Antioxidant Activities
- Gestational Diabetes Research and Management
- Blood Pressure and Hypertension Studies
- Eicosanoids and Hypertension Pharmacology
- Neurogenetic and Muscular Disorders Research
- RNA Research and Splicing
- Obesity, Physical Activity, Diet
- Vitamin D Research Studies
- Organic Electronics and Photovoltaics
- Circular RNAs in diseases
- Food composition and properties
- CRISPR and Genetic Engineering
- Organic Light-Emitting Diodes Research
Harbin Medical University
2012-2025
Qingdao University
2018-2025
Wangjing Hospital of China Academy of Chinese Medical Sciences
2021-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025
Chinese People's Liberation Army
2025
Tianjin Academy of Agricultural Sciences
2023-2025
Second Affiliated Hospital of Harbin Medical University
2012-2024
Southwest Forestry University
2023-2024
Animal Husbandry & Veterinary
2024
Zhejiang Ocean University
2023
Animals respond to environmental threats, e.g. looming visual stimuli, with innate defensive behaviors such as escape and freezing. The key neural circuits that participate in the generation of dimorphic remain unclear. Here we show behavioral patterns triggered by stimuli are mediated parvalbumin-positive (PV+) projection neurons mouse superior colliculus (SC). Two distinct groups SC PV+ form divergent pathways transmit threat-relevant signals parabigeminal nucleus (PBGN) lateral posterior...
N6-methyladenosine (m6A) RNA modification, a dynamic and reversible process, is essential for tissue development pathogenesis. However, the potential involvement of m6A in regulation cardiomyocyte (CM) proliferation cardiac regeneration remains unclear. In this study, we aimed to investigate role modification heart during postnatal adult injury. Methods results: identified downregulation demethylase ALKBH5, an "eraser" that responsible increased methylation, after birth. Notably, ALKBH5...
Cardiac hypertrophy is a precursor to heart failure and represents significant global cause of mortality, thereby necessitating timely effective therapeutic interventions. Zinc finger protein 36 (Zfp36) recognised as critical regulator ferroptosis; however, its role underlying mechanisms in cardiac remain largely unexplored. This study aims investigate the regulatory function Zfp36 ferroptosis within context hypertrophy. Single-cell sequencing analysis demonstrated reduction expression...
Superior kidding rate is an important economic trait in production of meat goat, and ovulation the precondition rate. MicroRNAs (miRNAs) play critical roles almost all ovarian biological processes, including folliculogenesis, follicle development, atresia, luteal development regression. To find out different activity recruitment with miRNA-mediated posttranscriptional regulation, small RNAs expressed pattern tissues multiple uniparous Anhui White goats during follicular phase was analyzed...
Pathological cardiac hypertrophy (CH) is a key factor leading to heart failure and ultimately sudden death. Long non-coding RNAs (lncRNAs) are emerging as new player in gene regulation relevant wide spectrum of human disease including disorders. Here, we characterize the role specific lncRNA named hypertrophy-associated regulator (CHAR) CH delineate underlying signalling pathway. CHAR was found markedly down-regulated both vivo mouse model induced by pressure overload vitro cellular...
Abstract Mesopolymers with high solubility, free of structural defects, and negligible batch‐to‐batch variation open a new avenue for organic optoelectronics. Organic light emitting transistors that combine the functions light‐emitting diodes field‐effect transistors. However, charge transport ability strength are contradictory within one conjugated polymer. Herein, three low‐molecular‐weight mesopolymers thienopyrroledione–benzothiadiazole repeating units (meso‐TBTF) were obtained. The show...
Abstract Researchers suggest that personal and contextual factors may interact to predict career calling; however, the antecedents of calling have received less research attention. Consequently, aim this is develop test a model investigates work engagement professional identity as mediators effect social support on among 456 Chinese special education teachers. Structural equation modeling analyses revealed perceived predicted high levels engagement, identity, calling. Furthermore,...
Background: Liver injury is the hallmark adverse reaction of endothelin receptor antagonist (ERA). Since first drug, bosentan has been widely used in clinical practice, hepatotoxicity accompanied by history ERA. The new ERA proven to have a lower liver risk but current research findings are inconsistent. ERA-based targeted drug combinations commonly treatment pulmonary arterial hypertension, where difficult estimate. Objectives: This study aimed compare correlation between and different...