A5085511601- Online and Blended Learning
- Technology-Enhanced Education Studies
- Poverty, Education, and Child Welfare
- Education Systems and Policy
- Computational Drug Discovery Methods
- Blood Coagulation and Thrombosis Mechanisms
- Cellular Mechanics and Interactions
- Lipid metabolism and biosynthesis
- Fibroblast Growth Factor Research
- Education and Communication Studies
- Malaria Research and Control
- Nuclear Structure and Function
- Soybean genetics and cultivation
- Alzheimer's disease research and treatments
- Transgenic Plants and Applications
- Student Stress and Coping
- Traumatic Brain Injury and Neurovascular Disturbances
- RNA modifications and cancer
- Biotin and Related Studies
- Education Practices and Challenges
- CRISPR and Genetic Engineering
- School Leadership and Teacher Performance
- Sphingolipid Metabolism and Signaling
- African Botany and Ecology Studies
- Mental Health and Well-being
Central University of Rajasthan
2016-2024
Tel Aviv University
2023
Gyan Vihar University
2022-2023
University of Delhi
2009-2010
Institut des Sciences des Plantes de Montpellier
2009
SUNY Downstate Health Sciences University
2008
Abstract Gefitinib, an EGFR tyrosine kinase inhibitor, is used as FDA approved drug in breast cancer and non-small cell lung treatment. However, this has certain side effects complications for which the underlying molecular mechanisms are not well understood. By systems biology based silico analysis, we identified off-targets of gefitinib that might explain drugs. The crystal structure EGFR-gefitinib complex was binding pocket similarity searches on a druggable proteome database (Sc-PDB) by...
Cn-AMP2 is an antimicrobial peptide derived from liquid endosperm of coconut (Cocos nucifera). It consists 11 amino acid residues and predicted to have high propensity for β-sheet formation that disposes this be amyloidogenic. In the present study, we examined amyloidogenic propensities in silico then tested predictions under vitro conditions. The study revealed possesses comparable with Aβ. Upon solubilisation agitation aqueous buffer, forms visible aggregates display bathochromic shift...
Severe acute respiratory syndrome novel coronavirus 2 (SARS-CoV-2) has caused the global pandemic as COVID-19, which is most notorious public health crisis in last 100 years. SARS-CoV-2 composed of four structural proteins and several non-structured proteins. The multi-facet nucleocapsid (N) protein major component CoVs, However, there are no dedicated genomic, sequences analyses focusing on potential roles N protein. Hence, an urgent requirement a detailed study SARS-CoV-2. Herein, we...
Accumulation of ordered protein aggregates (or amyloids) represents a hallmark many diseases (e.g., Alzheimer's disease, type II diabetes, Parkinson's etc.), results from intermolecular association partially unfolded proteins/ peptides. Such associations usually take place in highly crowded conditions. The aggregates, which are formed under vitro and vivo conditions exhibit substantial variations their structure function. heterogeneities amyloids might arise due to macromolecular crowding...
Plasminogen activator inhibitor-1 (PAI-1/Serpin E1) is classically known for its antifibrinolytic activity via inhibiting uPA and tPA of the fibrinolytic pathway. PAI-1 has a paradoxical role in tumor progression, molecular functions are poorly understood. widely accepted secretory protease inhibitor, however, study suggested localization cytoplasm nucleus. Besides plethora biological as protein, intracellular localization, remain unexplored at level. In this study, using various
Abstract Purpose Extracellular matrix remodeling is essential for extravillous trophoblast (EVT) cell migration and invasion during placental development regulated by metalloproteinases (MMPs) tissue inhibitors of metalloproteases (TIMPs). Sphingosine kinases (SPHK1 SPHK2) synthesize sphingosine‐1‐phosphate (S1P), which works either intracellularly or extracellularly via its receptors S1PR1‐5 in an autocrine paracrine manner. The role SPHKs/S1P regulating the expression MMPs TIMPs EVT mostly...
E-learning resources are the paths where a teacher trainee properly trained towards future teacher. Everywhere, every time can learn something new through e-resources. The present study aims to find utilization of e-learning among trainees school education. has been done with help survey method. This was descriptive methodology. Population this B.Ed. (two-year) SGVU, Jaipur. Data collected from 30 using purposive sampling It online google form. A Self-made questionnaire is prepared by...
The present study aims to find awareness of e-learning resources among B.Ed.-M.Ed. teacher trainees SGVU. Descriptive survey methodology is used. Population this was (Integrated) SGVU, Jaipur. Data collected from 30 with using purposive sampling method. A self-made questionnaire prepared by the researcher help google form for data collection and link has been sent trainees. findings have clearly indicated that, more aware about and, they used regularly in classroom.
Covid-19 pandemic has brought many pros along with it.This totally changed the working system of Indian education.The classroom teaching methodology been completely changed.Now teachers are students help internet access by sitting at their home place.However, have to face challenges accomplish objective and learning.Conducting online classes is itself a great challenge for who habitual conducting from years.The disrupted education sector globally.Classes suspended enforce social distancing...
The present study has been designed and formulated to discover the level of academic achievement personality development students studying in KGBVs. Also, it was done health facilities available research also intended teachers’ attitude towards education girls KGBVs, views principals, students, parents regarding basic facilities, amenities, security, other things Focus on girl child is very need time . rate generally low India An important step taken by government 10th five year plan...
<p>Kasturba Gandhi Balika Vidyalayas (KGBVs) were established in 2004 under the Sarva Shiksha Abhiyan (SSA) to provide education girls from disadvantaged backgrounds rural areas. These schools have been instrumental promoting girls' and reducing gender gap education. This article aims an overview of status KGBVs Rajasthan, India. </p>
<p>Kasturba Gandhi Balika Vidyalayas (KGBVs) were established in 2004 under the Sarva Shiksha Abhiyan (SSA) to provide education girls from disadvantaged backgrounds rural areas. These schools have been instrumental promoting girls' and reducing gender gap education. This article aims an overview of status KGBVs Rajasthan, India. </p>
Abstract Protein kinases of both the parasite and host are crucial in invasion survival might be drug targets against drug-resistant malaria. STK35L1 was among top five hits kinome-wide screening, suggesting a role malaria’s liver stage. The function malaria is not known yet. We found that highly upregulated during infection P. berghei HepG2 cells mice liver. Knockdown remarkably suppressed sporozoite hepatocytes. STAT3 phosphorylated sporozoites infection. activation required for...