Amalia Martínez de la Gándara
A5047636476- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Nutrition and Health in Aging
- Clinical Nutrition and Gastroenterology
- Extracellular vesicles in disease
- Nosocomial Infections in ICU
- SARS-CoV-2 and COVID-19 Research
- Thermal Regulation in Medicine
- MicroRNA in disease regulation
- Organ Transplantation Techniques and Outcomes
- Psychedelics and Drug Studies
- Inflammasome and immune disorders
- Renal Transplantation Outcomes and Treatments
- Genomic variations and chromosomal abnormalities
- Maternal and Perinatal Health Interventions
- E-commerce and Technology Innovations
- Therapeutic Uses of Natural Elements
- Assisted Reproductive Technology and Twin Pregnancy
- Immunotherapy and Immune Responses
- Antibiotic Use and Resistance
- Electrolyte and hormonal disorders
- Metabolism and Genetic Disorders
Hospital Universitario Infanta Leonor
2011-2025
Hospital San Pedro
2022
Hospital Del Mar
2022
Instituto de Investigación Sanitaria del Principado de Asturias
2022
Hospital de Mataró
2022
Hospital Universitario Río Hortega
2022
Universidad de Oviedo
2022
Hospital Universitario de Valme
2022
Universitat de Lleida
2021
Universitat Autònoma de Barcelona
2002
The primary aim of our study was to investigate the association between intubation timing and hospital mortality in critically ill patients with coronavirus disease 2019 (COVID-19)-associated respiratory failure. We also analysed both impact such throughout first four pandemic waves influence prior noninvasive support on outcomes.This is a secondary analysis multicentre, observational prospective cohort that included all consecutive undergoing invasive mechanical ventilation due COVID-19...
Although the prevalence of community-acquired respiratory bacterial coinfection upon hospital admission in patients with coronavirus disease 2019 (COVID-19) has been reported to be < 5%, almost three-quarters received antibiotics. We aim investigate whether procalcitonin (PCT) or C-reactive protein (CRP) could helpful biomarkers identify among COVID-19 pneumonia. carried out a multicentre, observational cohort study including consecutive admitted 55 Spanish intensive care units (ICUs). The...
Abstract Background Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study investigate associations between mortality and variables measured during first three days ventilation with intubated at ICU admission. Methods Multicenter, observational, cohort includes consecutive admitted 44 Spanish ICUs February 25 July 31, 2020, who required intubation admission for more than days. We collected demographic clinical data prior...
The identification of critically ill COVID-19 patients at risk fatal outcomes remains a challenge. Here, we first validated candidate microRNAs (miRNAs) as biomarkers for clinical decision-making in patients. Second, constructed blood miRNA classifier the early prediction adverse ICU.This was multicenter, observational and retrospective/prospective study including 503 admitted to ICU from 19 hospitals. qPCR assays were performed plasma samples collected within 48 h upon admission. A 16-miRNA...
Chemsex is the use of psychoactive substances, mainly gamma-hydroxybutyrate, 4-methylmethcathinone (mephedrone), and methamphetamines to facilitate enhance experience sexual intercourse. The toxicity these drugs may be problematic lead a fatal outcome in some patients. We present case 26-year-old man living with human immunodeficiency virus whose frequent mephedrone caused his death.
Background. Some patients previously presenting with COVID-19 have been reported to develop persistent symptoms. While this information has adequately recognised and extensively published respect non-critically ill patients, less is known about the incidence factors associated characteristics of COVID-19. On other hand, these very often intensive care unit-acquired pneumonia (ICUAP). A second infectious hit after COVID increases length ICU stay mechanical ventilation could an influence on...
The clinical heterogeneity of COVID-19 suggests the existence different phenotypes with prognostic implications. We aimed to analyze comorbidity patterns in critically ill patients and assess their impact on in-hospital outcomes, response treatment sequelae.Multicenter prospective/retrospective observational study intensive care units 55 Spanish hospitals. 5866 PCR-confirmed had comorbidities recorded at hospital admission; biological parameters, procedures complications throughout stay;...
Abstract Background Acute respiratory distress syndrome (ARDS) can be classified into sub-phenotypes according to different inflammatory/clinical status. Prognostic enrichment was achieved by grouping patients hypoinflammatory or hyperinflammatory sub-phenotypes, even though the time of analysis may change classification treatment response disease evolution. We aimed evaluate when clustered in more than 1 group, and how they clustering using data baseline day 3, prognosis their evolution...
Background: People with HIV (PWH) often have a suboptimal response to vaccines, raising concerns about the efficacy of coronavirus disease 2019 (COVID-19) vaccines in this population. We aimed evaluate humoral immune B.1 lineage and Omicron variant PWH following COVID-19 vaccination. Methods: conducted prospective study on 19 who received two-dose series mRNA vaccine booster six months later. Participants without infection were included as healthy control (HC) group. The (anti-SARS-CoV-2 S...
To evaluate the rate of malignant transformation oral erythroplakia and identify associated risk factors.
<b>Background:</b> Increasing evidence supports microRNAs (miRNAs) as potential biomarkers for the management of viral respiratory infections and critical patients. <b>Aim:</b> First, to validate candidate miRNAs clinical decision-making in COVID-19. Second, construct a miRNA panel early prediction fatal outcomes intensive care unit (ICU). <b>Methods:</b> Multicenter cohort study including 503 critically ill COVID-19 patients from 19 Spanish ICUs (CIBERESUCICOVID). A 16-miRNA qPCR panel,...
<b>Background:</b> The management of Post-Acute COVID-19 Sequelae (PASC), especially pulmonary sequelae, still remains a challenge. MicroRNAs (miRNAs) have potential use as biomarkers and could provide information on pathobiological mechanisms. <b>Aim:</b> First, to analyze the miRNAs quantified during ICU stay respiratory sequelae. Second, decipher molecular mechanisms associated with <b>Methods:</b> Multicenter study including 491 critically ill patients from 19 Spanish ICUs. Diffusing...