A5000395383- Hepatitis C virus research
- HIV/AIDS Research and Interventions
- Pneumonia and Respiratory Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV, Drug Use, Sexual Risk
- Cytomegalovirus and herpesvirus research
- Climate Change and Health Impacts
- HIV/AIDS drug development and treatment
- HIV-related health complications and treatments
- Air Quality and Health Impacts
- COVID-19 Clinical Research Studies
- Viral gastroenteritis research and epidemiology
- Pancreatic and Hepatic Oncology Research
- Hepatitis Viruses Studies and Epidemiology
- Bacterial Infections and Vaccines
- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- HIV Research and Treatment
- Health disparities and outcomes
- Vaccine Coverage and Hesitancy
- COVID-19 and healthcare impacts
- Liver Disease Diagnosis and Treatment
- Emergency and Acute Care Studies
- SARS-CoV-2 and COVID-19 Research
- Liver Disease and Transplantation
Instituto de Salud Carlos III
2014-2025
Centro de Investigación Biomédica en Red
2022-2025
Universidad Rey Juan Carlos
2016-2025
Hospital Universitario Río Hortega
2024
General Department of Preventive Medicine
2018
Comunidad de Madrid
2015-2016
Centro Nacional de Microbiologia
2014
Swansea University
2011
Chugai Pharma (United States)
2011
Hospital General Universitario Gregorio Marañón
2005
Sepsis has represented a substantial health care and economic burden worldwide during the previous several decades. Our aim was to analyze epidemiological trends of hospital admissions, deaths, resource expenditures, associated costs related sepsis twenty-first century in Spain. We performed retrospective study all sepsis-related hospitalizations Spanish public hospitals from 2000 2013. Data were obtained records Minimum Basic Set. The outcome variables sepsis, death, length stay (LOHS),...
Purpose We aim to assess if air pollution levels and climatological factors are associated with hospital admissions for exacerbation of chronic obstructive pulmonary disease (COPD) in Spain from 2004 2013. Methods conducted a retrospective study. Information on level were obtained the Spanish Meteorological Agency hospitalizations discharge database. A case-crossover design was used identify mortality. Postal codes assign climatic pollutant each patient. Results detected 162,338 COPD...
This study aimed to build an easily applicable prognostic model based on routine clinical, radiological, and laboratory data available at admission, predict mortality in coronavirus 19 disease (COVID-19) hospitalized patients. Methods: We retrospectively collected clinical information from 1968 patients admitted a hospital. built predictive score logistic regression which explicative variables were discretized using classification trees that facilitated the identification of optimal sections...
The aim of our study was to evaluate the seasonal variations and whether short-term exposure environmental risk factors, such as climate air pollution, is associated with PTB-related hospital admissions in human immunodeficiency virus (HIV)-infected patients Spain during era combined antiretroviral therapy (cART). A retrospective carried out using data from Minimum Basic Data Set (MBDS) State Meteorological Agency (AEMET) Spain. primary outcome variable PTB diagnosis. factors evaluated were...
Pneumococcal disease causes a high burden of in adults, leading to rates hospitalization, especially the elderly.All hospital discharges for pneumococcal and pneumonia among adults over 18 y age reported first diagnostic position 2011 (January 1, through December 31, 2011) were obtained.A total 10,861 due Spain with an annual incidence hospitalization 0.285 (CI 95%: 0.280–0.291) per 1,000 population old. Case-fatality rate was 8%. Estimated cost these hospitalisations more than 57 million...
The combination antiretroviral therapy (cART) has led to decreased opportunistic infections and hospital admissions in human immunodeficiency virus (HIV)-infected patients, but the intensive care unit (ICU) admission rate remains constant (or even increased some instances) during cART era. Hepatitis C (HCV) infection is associated with an risk for and/or mortality (particularly those related severe liver disease) compared general population. aim of this study was assess among HIV-infected...
Background Type 2 Diabetes (T2DM) is the most rapidly increasing risk factor for ischemic stroke. We aimed to compare trends in outcomes stroke people with or without diabetes Spain between 2003 and 2012. Methods selected all patients hospitalized using national hospital discharge data. evaluated annual incident rates stratified by T2DM status. analyzed use of diagnostic therapeutic procedures, patient comorbidities, in-hospital outcomes. calculated mortality (IHM), length stay (LOHS)...
Background and aims In comparison with men, women who use drugs (WWUD) have considerably more frequent intense experiences interpersonal violence, sexual abuse trauma. The aim of this study was to identify issues related gender-based vulnerability in a group WWUD attended harm reduction facility Madrid, Spain. Material methods A cross-sectional conducted during screening blood borne infections. We included (smoked or injected heroin/cocaine) were actively screened for HIV, HBV HCV setting...
We performed a nationwide population-based retrospective study to describe the epidemiology of bacterial co-infections in coronavirus disease 2019 (COVID-19)-hospitalized patients Spain 2020. also analyzed risk factors for co-infection, etiology and impact outcome.Data were obtained from records Minimum Basic Data Set (MBDS) National Surveillance System Hospital Spain, provided by Ministry Health annually published with 2 years lag. COVID-19 circulated two waves 2020: its introduction 31st...
This study aims to describe and analyze hospital admissions in Spain due rotavirus infections among children aged 5 years or under during the period 2001-2005, along with associated health cost.To update estimates of hospitalizations rates Spain, we conducted a retrospective national hospitalization data acute gastroenteritis using Minimum Basic Data Set.During period, total 17.1% all any etiology < = were attributable infection as determined by rotavirus-specific International...
Abstract SARS-CoV-2 reinfections have been frequent, even among those vaccinated. The aim of this study is to know if hybrid immunity (infection + vaccination) affected by the moment vaccination and number doses received. We conducted a retrospective in 746 patients with history COVID-19 reinfection recovered dates infection status (date doses). To assess differences time reinfection(t RI ) between unvaccinated, vaccinated before 6 months, later; comparing one, two or three (incomplete,...
Introduction Specific environmental factors may play a role in the development of Pneumocystis pneumonia (PCP) HIV‐positive patients. The aim this study was to estimate PCP incidence and mortality hospitalized patients Spain during combination antiretroviral therapy (cART) era (1997 2011), as well analyze climatological air pollution levels relation hospital admissions deaths. Methods We carried out retrospective study. Data were collected from National Hospital Discharge Database State...
Background: The introduction of highly active antiretroviral therapy (HAART) has influenced the incidence cancer in people with human immunodeficiency virus (HIV) infection. aim this study was to evaluate changes pattern rates HIV-infected children on HAART during over a decade follow-up. Patients and Methods: We carried out case-control study. Data were obtained from records minimum basic data set hospitals Spain 1999 2008. epidemiologic trends diagnoses evaluated through 3 calendar...
Background One reason for the aggressiveness of pancreatic cancer is that it diagnosed late, which often limits both therapeutic options are available and patient survival. The long-term survival patients not possible if tumor resected, even among who receive chemotherapy in earliest stages. main objective this study was to create a prediction model in-hospital mortality after pancreatectomy patients. Methods We performed retrospective all resections Spanish public hospitals (2013). Data...
This study aimed to assess the costs and clinical benefits of 13-valent pneumococcal conjugate vaccine (PCV13) administered annually 65-year-old cohort in Spain versus alternative not vaccinating patients treating them only when infected. Cases disease avoided were calculated through a dynamic model based on work Anderson May (1999). Sixty-six percent was assumed have been vaccinated with one PCV13 dose (304,492 subjects). Base-case estimated effectiveness serotype coverage 58% 60%,...
Background: We performed an epidemiologic study to analyze nationwide time trends in adult psychotropic drug use over a period from 2006 2012, and identify those factors associated with the likelihood of consumption these drugs during period; Methods: Cross-sectional on medication Spanish population. used secondary individualized data drawn 2012 National Health Surveys (SNHS). The dependent variable was previous two weeks. Independent variables included socio-demographic characteristics,...