A5100660866- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Analysis
- Shoulder Injury and Treatment
- Musculoskeletal pain and rehabilitation
- Orthopedic Surgery and Rehabilitation
- Myofascial pain diagnosis and treatment
- Foot and Ankle Surgery
- Pelvic and Acetabular Injuries
- Lower Extremity Biomechanics and Pathologies
- Diabetic Foot Ulcer Assessment and Management
- Sports injuries and prevention
- Cervical and Thoracic Myelopathy
- Hip disorders and treatments
- Scoliosis diagnosis and treatment
- Pancreatic and Hepatic Oncology Research
- Shoulder and Clavicle Injuries
- Cell Image Analysis Techniques
- Image Processing Techniques and Applications
- Healthcare and Venom Research
- Spondyloarthritis Studies and Treatments
- Acupuncture Treatment Research Studies
- Advanced Vision and Imaging
- Bone Metabolism and Diseases
- Bone and Joint Diseases
Third Affiliated Hospital of Southern Medical University
2020-2025
Changhai Hospital
2023-2025
Second Military Medical University
2023-2025
Southern Medical University
2015-2025
Nanfang Hospital
2025
Lanzhou Jiaotong University
2025
Fujian Agriculture and Forestry University
2024
Henan Normal University
2024
First People's Hospital of Foshan
2023
Zhujiang Hospital
2012-2023
Previous studies have revealed that melatonin could play a role in anti-osteoporosis and promoting osteogenesis. However, the effects of treatment on osteoporotic bone defect mechanism underlying angiogenesis are still unclear. Our study was aimed to investigate potential defect. Bone marrow mesenchymal stem cells (BMSCs) were isolated from femur tibia rats. The BMSC osteogenic ability assessed using alkaline phosphatase (ALP) staining, alizarin red S qRT-PCR, western blot,...
Abstract Although several morphological variations and classification of the suprascapular notch (SSN) were reported in western populations, little attention has been paid to this anatomic issue Chinese population. In research SSN morphology people, 295 specimens intact dry adult scapulas investigated measured thoroughly systematically. Morphological features observed by visual inspection, correlation parameters variability digital images with image processing software bones a vernier...
BACKGROUND Icariin (ICA), a natural flavonoid compound monomer, has multiple pharmacological activities. However, its effect on bone defect in the context of type 1 diabetes mellitus (T1DM) not yet been examined. AIM To explore role and potential mechanism ICA T1DM. METHODS The effects osteogenesis angiogenesis were evaluated by alkaline phosphatase staining, alizarin red S quantitative real-time polymerase chain reaction, Western blot, immunofluorescence. Angiogenesis-related assays...
Plasma cell-free DNA (cfDNA) fragmentomics has demonstrated significant differentiation power between cancer patients and healthy individuals, but little is known in pancreatic biliary tract cancers. The aim of this study to characterize the cfDNA biliopancreatic cancers develop an accurate method for detection. One hundred forty-seven with 71 non-cancer volunteers were enrolled, including 55 cholangiocarcinoma, 30 gallbladder cancer, 62 cancer. Low-coverage whole-genome sequencing (median...
Abstract Osthole, a natural coumarin derivative, has been shown to have multiple pharmacological activities. However, its effect on osteoporotic fracture not yet examined. This research was designed explore the unknown role and potential mechanism of osthole healing. We first evaluated osteogenic angiogenic abilities osthole. Then angiogenesis‐related assays were conducted investigate relationship between osteogenesis angiogenesis, further molecular mechanism. After that, we established...
Heterotopic ossification of the entheses is one most distinctive features in ankylosing spondylitis (AS). Fibroblasts are potential target cells for heterotopic ossification. The Wnt/β-catenin pathway and its inhibitor dickkopf-1 (DKK-1) regulate bone formation. DKK-1 expression human AS tissues has not been documented.The purpose current study was to investigate elucidate role fibroblasts proliferation osteogenesis AS.DKK-1 assessed by western blotting, real time-polymerase chain reaction...
Abstract Although several morphological variations of sacrum have been reported in western populations, little attention has paid to this anatomic issue eastern people, and classification sacral variability particular. In research morphology Chinese we investigated measured thoroughly systematically 203 specimens intact dry adult sacra. Morphological features were observed by visual inspection, correlation parameters with a vernier caliper. The incidence was calculated. We found that the...
Dickkopf-1 (DKK-1) has been proved dysfunctional in ankylosing spondylitis (AS), and decreased serum functional DKK-1 levels have identified to be AS patients. This study aims examine the relation of binding (functional) with radiographic severity AS.Total Dkk1 were assessed by commercial sandwich enzyme-linked immunosorbent assay measured using method 84 patients 79 healthy controls. The progression was classified according events modified New York Criteria for sacroiliac joints evaluation...
The effect on fat infiltration (FI) of paraspinal muscles in degenerative lumbar spinal diseases has been demonstrated except for spinopelvic parameters. present study is to identify the parameters FI muscle (PSM) and psoas major (PMM) patients with spondylolisthesis.
Bone morphogenetic proteins (BMPs) are part of the transforming growth factor beta (TGF-β) superfamily and play crucial roles in bone development, as well formation maintenance various organs. Triplophysa dalaica, a small loach fish that primarily inhabits relatively high elevations cooler water bodies, was focus this study. Understanding function BMP genes during morphogenesis T. dalaica helps to clarify mechanisms its evolution serves reference for study other bony fishes. The data...
Whether children's general foot pain related to specific posture remains unknown. The aim of the study was determine long-term dynamic characteristics in children with using smartphone-connected wearable sensors. Over a 30-day period, 94 (37 girls and 57 boys, mean age 9.3 years) completed study. Children were grouped according recent history during walking. Static rearfoot alignment digitally measured. Long-term gait collected sensors 10 m self-selected speed walking per day. There 81...
Putting pancreatic adenocarcinoma (PAAD) screening into perspective for high-risk individuals could significantly reduce cancer morbidity and mortality. Previous studies have profiled somatic mutations in PAAD. In contrast, the prevalence of PAAD predisposition genes has not been defined, especially Asian population. Using a multi-tier cohort design whole genome/exome sequencing, we create comprehensive germline mutation map 1,123 Chinese patients comparison with 11 pan-ethnic studies. For...
Abstract Localized scour of bridge abutments is one the important causes water damage, which seriously threatens normal operation bridges, so study its protective measures particularly important. In order to effect conductive fluid on protection local abutments, a three‐dimensional numerical model established based Flow‐3D software, and experimental data Ismael Adnan A are used verify reliability model. The verified then change in width bottom edge morphology cylindrical abutment effect....
This paper analyzed the causes of peripheral nerve injury induced by acupoint injection, and proposed methods for prevention. These included emphasizing physicochemical properties medications strengthening research on medication compatibility, classifying high-risk acupoints establishing international standards safe needling, standardizing clinical procedures incorporating ultrasound technology when necessary to improve accuracy safety procedure. strategies aimed reduce risk associated with...
Cranial sutures play critical roles in load distribution and neuroprotection, with their biomechanical performance intimately linked to morphological complexity. The purpose of this study was investigate the effect different morphologies cranial on behavior. Based sutures, six groups finite element models (closed, straight, sine wave, tight sinusoidal layered wave + sutural bone) bone–suture–bone composite structures that ranged from simple complex were constructed. Each model subjected 50...
The acromion can have different shapes and sizes among populations. Measuring the morphological structures of shoulder joint facilitate a better understanding causes SIS issues. study explores correlation between types measurements in Chinese population. A retrospective study. Between January 2024 September 2024, MRI 128 cases that were diagnosed as met criteria included Measurements taken from images acromion, humeral distance (AHD), index (AI), acromion-greater tubercle impingement (ATI),...
Background: Heterotopic ossification on the enthesis, which develops after subsequent inflammation, is one of most distinctive features in ankylosing spondylitis (AS). Prostaglandin E2 (PGE-2) serves as a key mediator inflammation and bone remodeling AS. Celastrol, well-known Chinese medicinal herb isolated from Tripterygium wilfordii , widely used treating inflammatory diseases, including It has been proven that it can inhibit lipopolysaccharide-induced expression various mediators, such...