A5027628105- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Respiratory Support and Mechanisms
- Long-Term Effects of COVID-19
- Respiratory and Cough-Related Research
- Obstructive Sleep Apnea Research
- Delphi Technique in Research
- COVID-19 Clinical Research Studies
- Pediatric health and respiratory diseases
- Thermal Regulation in Medicine
- Cardiovascular and exercise physiology
- Tuberculosis Research and Epidemiology
- Heart Rate Variability and Autonomic Control
- COVID-19 and Mental Health
- Intensive Care Unit Cognitive Disorders
- Musculoskeletal pain and rehabilitation
- Physical Activity and Health
- Infectious Diseases and Tuberculosis
- Dysphagia Assessment and Management
- Health and Wellbeing Research
- Tracheal and airway disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cardiac, Anesthesia and Surgical Outcomes
- Nutrition and Health in Aging
- Pressure Ulcer Prevention and Management
Istituti Clinici Scientifici Maugeri
2007-2024
University of Sassari
2021-2024
University of Groningen
2021
University of Insubria
2021
Nuovo Ospedale San Giovanni di Dio
2021
Fondazione Salvatore Maugeri
2011-2016
Respiratory Clinical Trials
2016
World Health Organization - Pakistan
2012
BACKGROUND: Increasing evidence suggests that post-TB lung disease (PTLD) causes significant morbidity and mortality. The aim of these clinical standards is to provide guidance on the assessment management PTLD implementation pulmonary rehabilitation (PR).METHODS: A panel global experts in field TB care PR was identified; 62 participated a Delphi process. 5-point Likert scale used score initial ideas for after several rounds revision document approved (with 100% agreement).RESULTS: Five were...
In hospitalized patients recovering from the SARS-coronavirus-2 disease 19 (COVID-19), high prevalence of muscle weakness and physical performance impairment has been observed.
The effect of pulmonary rehabilitation (PR) on the EuroQol Group's 5-dimension questionnaire (EQ-5D) in COPD has been poorly investigated. In addition, conflicting results were reported about visual analog scale component EQ-5D (EQ-VAS). purpose this study was to evaluate responsiveness EQ-VAS PR and its relationship with clinical functional parameters subjects COPD, as well define minimal clinically important difference (MCID) estimate for after PR.A total 468 in-patients stable...
Background: Individuals with COPD may present reduced peripheral muscle strength, leading to impaired mobility. Comprehensive pulmonary rehabilitation (PR) should include strength training, in particular lower limbs. Furthermore, simple tools for the assessment of performance are required. Objectives: To assess patients by sit-to-stand test (STST), as compared one-repetition maximum (1-RM), considered gold standard assessing non-laboratory situations, and evaluate responsiveness STST a PR...
The sit-to-stand (STS) test is a feasible tool for measuring peripheral muscle strength of the lower limbs. There evidence increasing use STS tests in patients with COPD. We sought to evaluate subjects COPD minimum clinically important difference 30-s after pulmonary rehabilitation.Stable undergoing and 6-min walk (6MWT) before rehabilitation were included. Responsiveness was determined by change results (Δ STS) rehabilitation. evaluated using an anchor-based method.96 moderate-to-severe At...
<b><i>Background:</i></b> International guidelines recommend the inclusion of patients with bronchiectasis in pulmonary rehabilitation (PR) to improve exercise capacity and health-related quality life (HRQoL). At present, effect PR these has been poorly investigated. <b><i>Objective:</i></b> The aim our retrospective analysis was evaluate effects predictors success for a program not related cystic fibrosis (non-CF bronchiectasis)....
Background: As Barthel Index (BI) quantifies motor impairment but not breathlessness, the use of only this index could underestimate disability in chronic respiratory disease (CRD). To our knowledge, no study evaluates both and CRD during activities daily living (ADLs) simultaneously with a unique tool. The objective was to propose for patients an additional tool dyspnea assessment ADLs based on BI items named dyspnea. Methods: Comprehensibility, reliability, internal consistency, validity,...
Background: Bronchial hyperresponsiveness (BHR), sputum eosinophilia, and bronchial reversibility are often thought to be a hallmark of asthma, yet it has been shown occur in COPD as well. Objectives: To evaluate the relationship between BHR, lung function, airway inflammation patients. Methods: Thirty-one, steroid-free patients with stable, mild moderate were studied. The following tests carried out: baseline reversibility, provocative dose methacholine causing 20% fall forced expiratory...
Airway eosinophilic inflammation is a characteristic of asthmatic patients and sub group COPD subjects. Blood eosinophils are deemed as good surrogate marker sputum inflammation; however, controversial data have been published particularly in COPD. The aim our study was to compare blood "real life". Sputum induced stable with or asthma hypertonic saline solution were evaluated. Frequency comorbidities recorded. Correlations performed stratifying by disease comorbidities. 146 patients, 57 89...
Abstract Objective The study aimed to evaluate whether high-flow oxygen therapy (HFOT) during training was more effective than in improving exercise capacity hypoxemic chronic obstructive pulmonary disease (COPD). Methods A total of 171 patients with COPD and hypoxemia were consecutively recruited 8 rehabilitation hospitals a randomized controlled trial. Cycle-ergometer used 20 supervised sessions at iso inspiratory fraction both groups. Pre- post-training endurance time (Tlim), 6-minute...
Abstract Background High blood eosinophils seem to predict exacerbations and response inhaled corticosteroids (ICS) treatment in patients with chronic obstructive pulmonary disease (COPD). The aim of our study was prospectively evaluate for 2 years, sputum COPD treated bronchodilators only at recruitment. Methods stable condition underwent monitoring lung function, eosinophils, comorbidities every 6 months years. ICS added during follow-up when symptoms worsened. Results 63 were enrolled: 53...
<h3>BACKGROUND:</h3> Asthma is defined by airway inflammation associated with various respiratory symptoms, and pharmacologic treatment based on inhaled corticosteroids bronchodilators. Physical activity, educational training, nutritional support, psychological counseling are considered part of non-pharmacologic treatment; however, studies so far have investigated the effect single treatment. There few that demonstrate comprehensive pulmonary rehabilitation, but no clear data available...
Background: Pulmonary Rehabilitation (PR) is a multimodal treatment that still poorly investigated in severe asthma where respiratory symptoms remain "uncontrolled" despite intensive pharmacological therapy. Bronchiectasis and obstructive sleep apnea (OSAS) are common comorbidities which may worsen control.Aim: Aim of the present study to investigate effectiveness PR on functional exercise, dyspnea, muscle fatigue patients with asthma.Methods: A total 317 affected from according GINA...
There are few studies evaluating (1) exercise capacity as assessed by the 6-minute walking distance (6MWD) test in large populations with obstructive sleep apnea (OSA); and (2) correlations patients' comorbidities.This study presents a cluster analysis performed on data of 1,228 patients. Severity limitation was defined basis 6MWD.Sixty-one percent showed (29.2% 31.9% mild severe limitation, respectively). About 60% 40% patients were included 1 (CL1) 2 (CL2), respectively. CL1 younger high...
BACKGROUND: The aim of these clinical standards is to provide guidance on 'best practice' care for the diagnosis, treatment and prevention post-COVID-19 lung disease.METHODS: A panel international experts representing scientific societies, associations groups active in disease was identified; 45 completed a Delphi process. 5-point Likert scale indicated level agreement with draft standards. final version approved by consensus (with 100% agreement).RESULTS: Four were agreed patients previous...
<i >Introduction</i>. Conflicting results have been so far reported about baseline lung function, as predicting factor of pulmonary rehabilitation (PR) efficacy. >Aim</i>. To ascertain whether or not function could predict a benefit in terms significant change 6-min walk test (6MWT) after PR. >Methods</i>. Seventy-five stable moderate-to-severe COPD inpatients with comorbidities (complex COPD), allocated to three-week PR program, were retrospectively evaluated. Pulmonary 6MWT, dyspnea...
BACKGROUND: The 6‐min walking test (6MWT) is responsive to physiological changes and pulmonary rehabilitation (PR) in patients with asthma. minimal clinically important difference (MCID) has not been established yet. OBJECTIVE: To determine the MCID of 6MWT METHODS: Using perceived change ability modified Medical Research Council (mMRC) score as anchors, receiver operating characteristic curves quantile regression, we evaluated before after PR these patients. St George Respiratory...
The sit-to-stand test (STST) is a feasible alternative for measuring peripheral muscle strength of the lower limbs. Our aim was to evaluate, in Chronic Obstructive Pulmonary Disease (COPD) patients, minimal clinically important difference (MCID) 30-second STST (30-STST) after pulmonary rehabilitation (PR). Stable COPD inpatients undergoing 30-STST and 6-minute walk (6MWT) before PR were included. Responsiveness determined by pre-to-post (∆) evaluation 30-STST. MCID evaluated using an...