A5040040359- Liver Disease Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- COVID-19 Clinical Research Studies
- Stroke Rehabilitation and Recovery
- Hepatitis B Virus Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Adipokines, Inflammation, and Metabolic Diseases
- Diet, Metabolism, and Disease
- Acute Ischemic Stroke Management
- Hepatitis C virus research
- Cardiovascular Health and Risk Factors
- Diabetes and associated disorders
- Health, Environment, Cognitive Aging
- Health Promotion and Cardiovascular Prevention
- Global Public Health Policies and Epidemiology
- Hepatitis Viruses Studies and Epidemiology
- Telemedicine and Telehealth Implementation
- Blood Pressure and Hypertension Studies
- Thyroid Cancer Diagnosis and Treatment
- Head and Neck Anomalies
- Sex and Gender in Healthcare
- Alcohol Consumption and Health Effects
- Sleep and Work-Related Fatigue
- Disaster Response and Management
- Trauma and Emergency Care Studies
University of Cape Coast
2014-2025
Kwame Nkrumah University
2023
Kwame Nkrumah University of Science and Technology
2023
Abstract Helicobacter pylori , a dominant member of the gastric microbiota, shares co-evolutionary history with humans. This has led to development genetically distinct H. subpopulations associated geographic origin host and differential disease risk. Here, we provide insights into population structure as part Genome Project ( Hp GP), multi-disciplinary initiative aimed at elucidating pathogenesis identifying new therapeutic targets. We collected 1011 well-characterized clinical strains from...
Metabolic syndrome (MetS) is a global health concern, especially for low and middle-income countries with limited resources information. The study's objective was to assess the prevalence of MetS in Freetown, Sierra Leone, using National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III), International Diabetes Federation (IDF) Harmonize ATP III. Additionally, we aimed establish concordance between these three different criteria used.
Background The leading cause of stroke remains atherosclerotic cardiovascular disease. World Health Organization/International Society Hypertension risk score represents an effort to produce a assessment tool for disease that is regionally specific. No previous work has described absolute scores among recent survivors in West Africa via this tool. Methods A cross-sectional analysis baseline data from the multicenter, phase III randomized, open-label, clinical trial, Phone-based Intervention...
The long-term impact of the coronavirus disease 2019 (COVID-19) pandemic on metabolic risk factors in different populations has not been fully investigated. Insulin resistance (IR) is a cardinal factor for development type 2 diabetes mellitus. current study sought to determine prevalence and determinants insulin selected Ghanaians with without past COVID-19 status Cape Coast Tamale metropolitan areas. Using cross-sectional design involving 510 adult participants, body mass index (BMI),...
Background Extraspinal findings are commonly detected on magnetic resonance imaging of the lumbar spine, but these sometimes omitted from radiological reports. Failing to report could have a clinical impact patients. The purpose this study was determine prevalence and reporting rates extraspinal spine imaging. Methods Retrospective analysis done images at Korle-Bu Teaching Hospital between January 2020 December 2021. A total 1267 patients underwent within period. degree significance...
Liver-related diseases, including liver cirrhosis and hepatocellular carcinoma (HCC), are significant causes of mortality globally. Specific predictors liver-related in low resource settings require assessment to help inform clinical decision making develop strategies for improved survival. The objectives this study were determine the proportion deaths associated with cirrhosis, HCC, their known risk factors, secondly in-hospital among HCC patients Ghana. We first performed a cross-sectional...
Data are needed to inform hepatitis B virus (HBV) testing and treatment policies in Ghana make progress towards achieving the 2030 WHO elimination targets. This study investigated patterns for HBV described age, sex, region-specific prevalence of infection using hospital data.A nationwide multi-centre cross-sectional was performed where hospital-based registers were reviewed. These included review 139,966 laboratory, 169,048 blood bank, 83,920 delivery register entries from 22 healthcare...
Objective To investigate the prevalence of cardiometabolic risk factors (CMRFs), target organ damage (TOD) and its associated among adults in Freetown, Sierra Leone. Design This community-based cross-sectional study used a stratified multistage random sampling method to recruit adult participants. Setting The health screening was conducted between October 2019 2021 Western Area Urban, Participants A total 2394 Leoneans aged 20 years or older were enrolled. Outcome measure Anthropometric...
Although most women would want to wait for more than two years before having another baby, their fertility behaviours during the first year following birth may decrease or increase length of interval. The objectives this study were to: assess how protected postpartum in Mfantseman municipal against pregnancy, based on patterns amenorrhoea and sexual abstinence; determine timing contraception relation predictors contraceptive use.This was a prospective carried out Municipality Central region...
The current burden of Hepatitis C virus infection and the availability HCV-related services in Ghana are not well described. Previous estimates on HCV seroprevalence country outdated. This study investigated testing treatment capacity Ghana. A multi-centre cross-sectional was conducted which laboratory blood bank registers from 17 public healthcare institutions were reviewed. survey cost also performed. Crude pooled seroprevalence, frequency median available diagnostic tests medicines crude...
To explore the effects of fee paying status on migration intentions Ghanaian medical students.Cross sectional questionnaire based survey.All established schools with students in their clinical years.Fee-paying and non-fee-paying years.None.Migration after graduation, Allegiance to Government Ghana.Approximately half (49%) surveyed had migrating school. Over 48% those plan doing so immediately completing house job, while 44% migrate at least one year job. The most popular destination chosen...
Helicobacter pylori ( H. ) is a gram-negative bacterium that colonizes the human stomach. Infection with this microaerophilic causes gastric and duodenal ulcer. This study sought to isolate , from biopsy samples of dyspeptic patients in Ghana using 2,3,5-triphenyltetrazolium chloride (TTC) dye incorporated medium method. TTC method was further used an antimicrobial susceptibility assay involving Dissotis rotundifolia extract (DRE). were successfully isolated patients. Pure cultures seen as...
Scant West African data on non-alcoholic fatty liver disease (NAFLD) means there is little representation of this population in the modelling used to derive biomarkers and predictive indices for risk stratification patients presence hepatic steatosis. This study evaluates performance index (FLI), steatosis (HSI) triglyceride-glucose (TyG) its derivatives predicting ultrasound detected NAFLD a locally resident Ghanaian participants.A post hoc analysis from cross sectional assessment...
This study compares levels of insulin resistance and beta-cell function their relationship with liver enzymes in recovered COVID-19 participants uninfected counterparts a cross-sectional design the Tamale metropolis Ghana. Biochemical indices for function, lipid metabolism, inflammation oxidative stress were assessed under fasting state 110 116 participants. The homeostatic model assessment (HOMA-IR) triglyceride-glucose index (TyG) employed resistance. Recovered presented lower (P < 0.05)...
Background: Scientific information on the impact of malaria risk developing type 2 diabetes mellitus (T2DM) after recovery from coronavirus disease 2019 (COVID-19) is limited in Ghanaian context. The purpose this study was to examine association between selected markers T2DM falciparum patients post-COVID-19 or not at a tertiary hospital Ghana.
 Methodology: This descriptive cross-sectional comparative 38-recovered COVID-19 adult participants with and 40 unexposed adults Tamale Teaching...
In spite of the negative effects coronavirus disease 2019 (COVID-19) on global health system, its long-term impact evolution diabetes is not fully ascertained. The current study was therefore designed to examine diabetogenic risk adults who had recovered from COVID-19 compared with their counterparts without any history condition in Cape Coast metropolis Ghana. This cross-sectional involved 110 and unexposed respondents. Weight, height, hip circumference (HC) waist (WC) were measured for...
Abstract Background and Aim Goiter is a major source of morbidity in the world, especially developing where dietary iodine deficiency, known cause this condition, endemic. The diagnosis mostly by ultrasonography (USG) scan, which can give anatomical, pathological, functional information for management goiter. This study aimed to determine commonest ultrasound findings goiter Ghana. Method records all 213 patients with diagnosed USG scan over 5‐year period were retrieved. Data collected...