- Lung Cancer Treatments and Mutations
- Colorectal Cancer Treatments and Studies
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Lung Cancer Diagnosis and Treatment
- Anesthesia and Pain Management
- Hepatitis B Virus Studies
- Steroid Chemistry and Biochemistry
- Air Quality and Health Impacts
- Ferroptosis and cancer prognosis
- Intraoperative Neuromonitoring and Anesthetic Effects
- Advanced Breast Cancer Therapies
- Cancer-related molecular mechanisms research
- Acupuncture Treatment Research Studies
- Lung Cancer Research Studies
- Electromagnetic Launch and Propulsion Technology
- Liver Diseases and Immunity
- Metal and Thin Film Mechanics
- Evaluation and Optimization Models
- Bach Studies and Logistics Development
- Pain Management and Treatment
- HER2/EGFR in Cancer Research
- Maritime Ports and Logistics
- RNA Research and Splicing
- Cancer Genomics and Diagnostics
Chinese Academy of Medical Sciences & Peking Union Medical College
2006-2024
Guang’anmen Hospital
2024
Huazhong University of Science and Technology
2021-2023
Wuhan Union Hospital
2019-2023
Shanghai Medical Information Center
2023
Nanjing University of Science and Technology
2023
Yang Hospital
2020
Wuhan University of Technology
2008-2010
Peking Union Medical College Hospital
2006
The gastric cancer-derived extracellular vesicle miR-431-5p can induce ferroptosis in cancer cells by downregulating the levels of SLC7A11 and GPX4, thereby inhibiting occurrence development cancer. Currently, drug design based on this mechanism is not yet fully developed. Therefore, focusing critical inhibition target GPX4 within pathway, we utilized emerging AI tools for complete protein prediction design. We used AlphaFold2 to predict structure visualized its model using PyMOL, analyzed...
Purpose . To determine the efficacy of electroacupuncture on recovering postanesthetic bladder function. Materials and Methods Sixty‐one patients undergoing spinal anaesthesia were recruited allocated into or control group randomly. Patients in received therapy whereas ones not given any intervention. Primary endpoint was incidence overdistension postoperative urinary retention. Secondary endpoints included time to spontaneous micturition, voided volume, adverse events. Results All (31 30...
Background The objective of this study is to the adverse effects coal mining environment on workers discover early effective biomarkers. Methods molecular epidemiological was conducted with 502 in-service workers, who were divided into miner and auxiliary. We measured individual levels dust exposure for participants. Clinical examinations by qualified doctors. Peripheral blood collected measure biochemistry, hemogram, karyocyte apoptosis. Results All healthy have not found any diseases that...
This paper presents a study to easily and effectively evaluate the rationality of road network structure in container terminal yard. The fuzzy systematic evaluation method, which is found planning theory on city traffic network, used set quantitative parameters derived. A simple criterion based calculated value above proposed directly make decisions. effectiveness approach verified through case apply design new terminal.
Abstract The mechanisms of propellant gas chemical erosion on gun barrel materials are discussed creatively from a microscopic perspective molecular diffusion and intermolecular interaction. influence high-temperature high-pressure atoms the shallow surface microstructure material is theoretically analyzed using dynamics simulation method, which can be used as new idea for further study mechanism. results show that into characterized by significant longitudinal distribution characteristics...
Objective: To study the correlation between level of T-bet expression and liver damage in peripheral plasma cells patients with autoimmune hepatitis (AIH) order to provide reference for pathogenesis development diseases. Methods: The venous blood clinical examination data 29 cases AIH 6 healthy volunteers were collected. percentage subpopulations B proportion T-bet(+) each subgroup detected by flow cytometry. Plasma (CD19(+)CD10(-)CD27(hi)CD38(hi)), primary (CD19(+)CD10(-)CD27(-)IgD(+)),...
Abstract Background Nicotinamide Nucleotide Transhydrogenase-antisense RNA1 (NNT-AS1) is one of long non coding RNA, has been shown with high levels in several types cancers. However, the molecular mechanism remains to be revealed for NNT-AS1 progession hepatocellular carcinoma (HCC). TGF-β signaling pathway identified as negative factor excessive immunological response. We sought investigate effects mediating T cells infiltration by regulating patients HCC. Methods RNAscope In Situ...