A5039500320- Hearing Loss and Rehabilitation
- Neuroscience and Music Perception
- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Multisensory perception and integration
- Dementia and Cognitive Impairment Research
- Emotion and Mood Recognition
- Sleep and related disorders
- Advanced Neuroimaging Techniques and Applications
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mental Health Research Topics
- Speech and Audio Processing
- COVID-19 and Mental Health
- Neural dynamics and brain function
- Health disparities and outcomes
- Aging and Gerontology Research
- Health, Environment, Cognitive Aging
- Sleep and Work-Related Fatigue
- Psychosomatic Disorders and Their Treatments
- Psychological and Temporal Perspectives Research
- Personality Disorders and Psychopathology
- Phonetics and Phonology Research
- Workplace Health and Well-being
- Obsessive-Compulsive Spectrum Disorders
- Stress Responses and Cortisol
Peking University
2016-2025
Dalian Medical University
2025
Peking University Third Hospital
2022-2025
King University
2022-2024
Chinese Institute for Brain Research
2013-2024
Zhujiang Hospital
2024
Southern Medical University
2024
Air Force Medical University
2023-2024
Shanghai Fudan Microelectronics (China)
2024
Fudan University
2024
Background: The metalloprotease ADAMTS-7 (a disintegrin and metalloproteinase with thrombospondin type 1 motif 7) is a novel locus associated human coronary atherosclerosis. deletion protects against atherosclerosis vascular restenosis in rodents. Methods: We designed 3 potential vaccines consisting of distinct B cell epitopic peptides derived from conjugated the carrier protein KLH (keyhole limpet hemocyanin) as well aluminum hydroxide an adjuvant. Arterial ligation or wire injury was used...
Abstract Background The outbreak of Corona Virus Disease (COVID-19) in 2019 has continued until now, posing a huge threat to the public’s physical and mental health, resulting different degrees health problems. As vulnerable segment public, anxiety is one most common problems among COVID-19 patients. Excessive aggravates psychological symptoms patients, which detrimental their treatment recovery, increases financial expenditure, affects family relations, adds medical burden. Objective This...
Affective temperaments have been considered antecedents of major depressive disorder (MDD). However, little is known about how the covariation between alterations in brain activity and distinct affective work collaboratively to contribute MDD. Here, we focus on insular cortex, a critical hub for integration subjective feelings, emotions, motivations, examine neural correlates their relationship symptom dimensions.Twenty-nine medication-free patients with MDD 58 healthy controls underwent...
Nurses have a high incidence of insomnia. Insomnia not only damages the physical and mental health nurses, but also reduces their productivity quality care, ultimately affecting patient care. Over past 30 years, large number epidemiological surveys shown that insomnia in nurses is associated with occupational stress. As an external feature role nurse, stress difficult to alter short period time. Therefore, it necessary discuss complex mediating variables relationship between order find...
BACKGROUND: Hypothyroidism leads to multiple organ dysfunction, with the heart most affected. However, pathologic mechanism of hypothyroidism-induced failure remains be completely elucidated. Thyroid hormone replacement therapy enhances myocardium systolic function but increases occurrence arrythmias. There is an urgent need explore these mechanisms in detail and discover develop drugs that can target manage patients hypothyroidism. METHODS: In this study, a mouse model was established...
(1) Background: Cognitive decline is associated with instrumental activities of daily living (IADL) disability. Intervention targeting the mediators this association will provide a path to avoid cognition-related IADL (2) Methods: This study used data wave 2008 (baseline) and 2014 Chinese Longitudinal Healthy Longevity Surveys. Structural equation modeling was conducted examine mediating effect social interaction, lifestyle (fruit vegetable intake; exercise habits), depressive status on...
Ischemia preconditioning (IPC) ameliorates coronary no-reflow induced by ischemia/reperfusion (I/R) injury, and pericytes play an important role in microvascular function. However, it is unclear whether IPC exerts a protective effect on microcirculation regulates the pericytes. The purpose of this study was to assess improves perfusion reduces pericyte constriction after myocardial I/R injury. Rats were randomly divided into three groups: sham group, + group. left anterior descending artery...
Background Coronary microvascular dysfunction (CMD) is a pathophysiological feature of diabetic heart disease. However, whether sodium-glucose cotransporter 2 (SGLT2) inhibitors protect the cardiovascular system by alleviating CMD not known. Objective We observed protective effects empagliflozin (EMPA) on CMD. Materials and methods The mice were randomly divided into db/db group + EMPA group, db/m served as controls. At 8 weeks age, was given 10 mg/(kg⋅d) gavage for weeks. Body weight,...
Background People with schizophrenia recognize speech poorly under multiple-people-talking (informational masking) conditions. In reverberant environments, direct-wave signals from a source are perceptually integrated the reflections (the precedence effect), forming perceived spatial separation (PSS) between different sources and consequently improving target-speech recognition against informational masking. However, brain substrates underlying schizophrenia-related vulnerability to masking...
Under a "cocktail-party" listening condition with multiple-people talking, compared to healthy people, people schizophrenia benefit less from the use of visual-speech (lipreading) priming (VSP) cues improve speech recognition. The neural mechanisms underlying unmasking effect VSP remain unknown. This study investigated brain substrates in listeners and schizophrenia-induced changes substrates. Using functional magnetic resonance imaging, activation connectivity for contrasts vs. visual...
Fatigue is a universal and challenging problem in nurse's career, particularly for those working the emergency department. Through analyzing current status of department nurses' fatigue, purpose this study to provide guidance occupational health promotion strategies making fatigue relief.Cross-sectional was conducted among nurses 6 grade III A hospitals Xi'an, China. Convenience sample 346 agreed participate study. Data collection based on questionnaires. Descriptive statistics, hypothesis...
Older adults with subjective cognitive decline are at increased risk of future pathological and dementia. Subjective memory is an early sign decline; preventing or slowing in at-risk populations remains elusive issue. This study aimed to examine the trajectories factors older decline. Latent growth curve models (LGCMs) were fitted function among 1465 (aged 60+ years) Data obtained from four waves China Health Retirement Longitudinal Study (CHARLS, 2011–2018), which a large nationally...
Patients with schizophrenia (SCH) have deficits in source monitoring (SM), speech-in-noise recognition (SR), and auditory prosody recognition. This study aimed to test the covariation between SM SR alteration induced by negative prosodies their association psychiatric symptoms SCH.
Under 'cocktail party' listening conditions, healthy listeners and with schizophrenia can use temporally pre-presented auditory speech-priming (ASP) stimuli to improve target-speech recognition, even though are more vulnerable informational speech masking.Using functional magnetic resonance imaging, this study searched for both brain substrates underlying the unmasking effect of ASP in 16 controls 22 patients schizophrenia, schizophrenia-related speech-recognition deficits under...
Objectives This study aimed to investigate the relationship between disability and domain-specific cognitive function in older adults with chronic obstructive pulmonary disease (COPD). Design Cross-sectional analyses combined retrospective longitudinal analyses. Setting We included 450 communities China. Participants In this study, 1022 (mean age: 68.6±6.3; 612 males) 152 67.0±5.2; 83 COPD from China Health Retirement Longitudinal Study were a cross-sectional multivariate linear regression...