- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Energy and Environment Impacts
- Bone health and osteoporosis research
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Atrial Fibrillation Management and Outcomes
- Cervical and Thoracic Myelopathy
- Acupuncture Treatment Research Studies
- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Global Health Care Issues
- Fluorine in Organic Chemistry
- Birth, Development, and Health
- Stroke Rehabilitation and Recovery
- Pharmacological Effects of Natural Compounds
- Oxidative Organic Chemistry Reactions
- Global Cancer Incidence and Screening
- Cardiac electrophysiology and arrhythmias
- Cancer Treatment and Pharmacology
- Intracranial Aneurysms: Treatment and Complications
- Graphene and Nanomaterials Applications
- Neurological Disease Mechanisms and Treatments
- Cancer Diagnosis and Treatment
- Bone Metabolism and Diseases
Second Military Medical University
2022-2025
Shihezi University
2024-2025
Changhai Hospital
2022-2025
Wuhan University
2001-2024
Wangjing Hospital of China Academy of Chinese Medical Sciences
2017-2024
Southern Medical University
2015-2024
Guangdong Provincial People's Hospital
2024
Guangzhou Center for Disease Control and Prevention
2024
South China University of Technology
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2024
Silyl enol ethers react with bicyclo[1.1.0]butanes (BCBs) through Yb(OTf)
This study aimed to evaluate the role of tumor marker carbohydrate antigen (CA) 125 (CA125), CA19-9, carcinoembryonic (CEA) and Krebs von den Lungen-6 (KL-6) in diagnosis determination severity interstitial lung disease (ILD) rheumatoid arthritis (RA) patients. A retrospective analysis was performed. Fifty RA patients (24 with ILD 26 without ILD), 10 healthy subjects 14 other connective tissue disease-associated were included. Serum levels KL-6 markers CA125 CEA measured. Chest HRCT scored...
Background Neurological involvement and psychiatric manifestations have been documented in clinical cases of inflammatory bowel disease (IBD); however, the presence a causal relationship remains elusive. The objective this study is to investigate modifications occurring cerebral cortex as result IBD. Methods A compendium data extracted from genome-wide association (GWAS) involving maximum 133,380 European subjects. series Mendelian random analyses were applied exclude heterogeneity...
As the world experiences a demographic shift towards aging populations, there will be significant surge in number of sarcopenia patients, along with an unprecedented expansion associated economic burden. The multitudinous risk factors for have been reported, but evidence air pollution remains rare.This cross-sectional study employed multi-stage random sampling to select 1592 participants over 40 years age from Hubei Province. Daily mean concentrations pollutants were collected...
Abstract Liver cancer, a chronic non-communicable disease, represents serious public health problem. Long-term trends in the burden of liver cancer disease are heterogeneous across regions. Incidence and mortality based on Global Burden Disease, were collected from Chinese Centre for Disease Control Prevention. Age–period–cohort model was utilized to reveal secular estimate age, period cohort effects primary due specific etiologies. Both age-standardized incidence rate Hubei province rise,...
The disease burden of colorectal cancer in East Asia has been at a high level. However, the epidemiological characteristics this region have not systematically studied.
// Chun-Ting Hu 1, 2 , Li-Li Guo Na Feng Lei Zhang 3 Zhou 1 Ma Lan Shen Gui-Hui Tong Qian-Wen Yan Shi-Jie Zhu Xiu-Wu Bian 4 Mao-De Lai 5 Yong-Jian Deng Yan-Qing Ding Department of Pathology, Nanfang Hospital and School Basic Medical Sciences, Southern University, Guangzhou 510515, China Guangdong Provincial Key Laboratory Molecular Tumor General Surgery, Renji Hospital, Shanghai Jiaotong University Medicine, 200127, Southwest Third Military Chongqing 400038, Zhejiang Hangzhou 310006,...
Previous observational studies have found that fistulas are common in Crohn's disease (CD) and less ulcerative colitis (UC). However, some patients a fistula before diagnosis. Based on retrospective analysis, it was not possible to determine whether there bi-directional causal relationship between inflammatory bowel (IBD) fistulas.Data were extracted from the open GWAS database; 25,042 cases 34,915 controls included for IBD, 6926 30,228 fistula. Two-sample Mendelian randomization...
A Lewis acid-promoted [2π+2σ] cycloaddition strategy enables the construction of bicyclo[2.1.1]hexanes (BCHs) from enol ethers and bicyclo[1.1.0]butanes (BCBs), with excellent functional group tolerance observed for both reactants. Successful scale-up experiments further derivatization BCHs demonstrate robustness this methodology accessing complex carbocyclic frameworks.
A series of compounds featuring a novel bispiro[indanedione-oxindole-cyclopropane] moiety have been synthesized through squaramide-catalyzed [2+1] cycloaddition reaction. The tandem Michael-alkylation reaction 2-arylidene-1,3-indanediones with 3-bromooxindoles furnished the cycloadducts in high yields excellent diastereo- and enantioselectivities. ammonium ylide catalytic process, as key intermediate, was revealed by high-resolution mass spectrometry study.
Objective: To investigate the effect of exposure to multiple ambient air pollutants during pregnancy on risk children being born small for gestational age (SGA). Methods: An Air Pollution Score (APS) was constructed assess effects exposed six simultaneously, PM2.5, PM10, SO2, NO2, CO, and O3 (referred as joint exposure). A logistic regression model applied estimate associations APS SGA. Results: The adjusted odds ratios (ORs) SGA per 10 ug/m3 increased in first second trimesters entire were...