A5071944059- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Venous Thromboembolism Diagnosis and Management
- Medical Imaging and Analysis
- Neurological and metabolic disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Spinal Fractures and Fixation Techniques
- Blood disorders and treatments
- Neurological Complications and Syndromes
- Anesthesia and Pain Management
- Systemic Lupus Erythematosus Research
- Neurological Disorders and Treatments
- Substance Abuse Treatment and Outcomes
- Cerebral Venous Sinus Thrombosis
- Cell Adhesion Molecules Research
- Nausea and vomiting management
- Ophthalmology and Eye Disorders
- Glaucoma and retinal disorders
- Obstructive Sleep Apnea Research
- Radiomics and Machine Learning in Medical Imaging
- Peripheral Artery Disease Management
- Advanced X-ray and CT Imaging
- Trauma Management and Diagnosis
- Spinal Cord Injury Research
Seoul National University Hospital
2020-2025
Seoul Metropolitan Government
2018
Seoul National University
2018
Boramae Medical Center
2018
Sungkyunkwan University
2011-2014
Keimyung University
2014
Samsung (South Korea)
2011
Introduction: Diffusion-weighted imaging (DWI) is key for detecting acute ischemic brain lesions but struggles with hyperacute or small that mimic artifacts. This randomized crossover trial assessed whether an artificial intelligence (AI) solution enhances diagnostic accuracy these challenging compared to conventional interpretation. Methods: From February 2017 November 2021, 4,071 suspected stroke patients underwent initial and follow-up DWI. A neurologist based on medical records, a...
Abstract Purpose To validate JLK-LVO, a software detecting large vessel occlusion (LVO) on computed tomography angiography (CTA), within multicenter dataset. Methods From 2021 to 2023, we enrolled patients with ischemic stroke who underwent CTA 24-hour of onset at six university hospitals for validation and calibration datasets another hospital an independent dataset testing model calibration. The diagnostic performance was evaluated using area under the curve (AUC), sensitivity, specificity...
Abstract Background This multicenter clinical trial evaluated the stand-alone efficacy and improvements in diagnostic accuracy of early-career physicians using a deep learning-based software to detect large vessel occlusion (LVO) CT angiography (CTA). Methods pivotal included 595 ischemic stroke patients from January 2018 September 2023. Standard reference LVO locations (intracranial internal carotid artery [ICA], M1, or M2) were determined by consensus among three expert vascular...
We developed and externally validated a fully automated algorithm using deep learning to detect large vessel occlusion (LVO) in computed tomography angiography (CTA).
Background We compared the ischemic core and hypoperfused tissue volumes estimated by RAPID JLK-CTP, a newly developed automated computed tomography perfusion (CTP) analysis package. also assessed agreement between two software packages against early follow-up infarct on diffusion-weighted images (DWI). Methods This retrospective study analyzed 327 patients admitted to single stroke center in Korea from January 2021 May 2023, who underwent CTP scans within 24 h of onset. The concordance...
Although it has been reported that the amount of alcohol consumption a J-shaped association with ischemic stroke, is unclear whether differences in drinking patterns affect this relationship. We aimed to clarify impact on stroke midlife.We used data from National Health Insurance Service-National Sample Cohort, which large-sized, standardized population cohort Korea. Five different were defined by combining frequency and quantity consumed per occasion, is, abstainers, not alcohol; drinker...
Background To evaluate the stand-alone efficacy and improvements in diagnostic accuracy of early-career physicians artificial intelligence (AI) software to detect large vessel occlusion (LVO) CT angiography (CTA). Methods This multicenter study included 595 ischemic stroke patients from January 2021 September 2023. Standard references LVO locations were determined by consensus among three experts. The AI was benchmarked against standard references, its impact on four residents involved care...
Although it is not recognized as essential to test for antiphospholipid antibody (aPL) in stroke of unknown cause, aPL-related may account a considerable number cryptogenic strokes. We aimed assess the current status and diagnostic value aPL testing patients.Consecutive patients admitted with acute ischemic were examined confirm factors associated performing positive results real-world practice. Cryptogenic separately same manner. The profiles positivity compared by age.Among 2947 patients,...
ABSTRACT Background We compared the ischemic core and hypoperfused tissue volumes estimated by RAPID JBS-10K, a newly developed automated CT perfusion (CTP) analysis package. also assessed agreement between two software packages against early follow-up infarct on diffusion-weighted images (DWI). Methods This retrospective study analyzed 327 patients admitted to single stroke center in Korea from January 2021 May 2023, who underwent CTP scans within 24 hours of onset. The concordance...
Abstract Background To validate JLK-CTL, an artificial intelligence (AI) software developed to predict large vessel occlusion (LVO) using non-contrast CT (NCCT) scans, and investigate its clinical implications regarding both infarct volume functional outcomes. Methods Between January-2021 April-2023, a consecutive series of patients who concurrently underwent angiography NCCT within 24 hours last- known-well (LKW) were collected. LVO was confirmed through consensus among three experts...
Abstract Background The hyperdense artery sign (HAS) in patients with large vessel occlusion (LVO) is associated outcomes after ischemic stroke. Considering the labor-intensive nature of manual segmentation HAS, we developed and validated an automated HAS algorithm on non-contrast brain CT (NCCT) images using a multicenter dataset independent annotations by two experts. Methods For training dataset, included stroke undergoing concurrent NCCT angiography between May 2011 December 2022 from...
Objective Computed tomography perfusion (CTP) imaging is crucial in quantifying cerebral blood flow (CBF) and thereby making an endovascular treatment (EVT) after large vessel occlusion. However, CTP prone to overestimating the ischemic core. We sought delineate optimal regional CBF (rCBF) thresholds of pre‐EVT CTP. Methods collected acute stroke patients due occlusion who achieved successful recanalization with baseline CTP, immediate post‐EVT diffusion‐weighted image (DWI) within 3 hours,...
The causes of sudden death after medullary infarction involve arrhythmia, central respiratory failure, and dysautonomia. Sudden cardiac arrest in a is uncommon. Most these cases experienced cardiopulmonary within 2 weeks from stroke onset as the extent lesion increased. Here, we report two presenting arrest. These indicate that could be one Key Words: Medulla oblongata, Stroke, Heart
Ocular cranial nerve palsy of presumed ischemic origin (OCNPi) is the most common type ocular (OCNP) in patients aged ≥ 50 years; however, no definite diagnostic test exists. As criteria include clinical improvement, diagnoses are often delayed. Diagnostic biomarkers for OCNPi required; we hypothesized that cerebral small vessel disease associated with OCNPi. We analyzed 646 consecutive years isolated unilateral OCNP who underwent work-ups at two referral hospitals. White matter...
A 21-year-old female patient complaining of hemiparesis was diagnosed with right middle cerebral artery infarction. No risk factor found, despite an extensive young-age stroke work-up, except her history marijuana use. The had smoked for treating depression more than five years. Magnetic resonance angiography showed multifocal intra- and extracranial stenoses, suggesting cannabinoid-induced vasculopathy. Since the use illicit drugs has increased nationwide, physicians should consider it as a...
Background: Recent clinical evidence supports the early initiation of aspirin and clopidogrel combination for patients with minor stroke or high-risk transient ischemic attack (TIA) to prevent recurrence. However, some still experience neurological deterioration (END) despite optimal antithrombotic treatment. We investigated laboratory variables related END after treatment among non-cardioembolic TIA. Methods: The deficit who received within 24 hours symptom onset were selected from...