Hongwei Zhao

ORCID: 0000-0003-2666-1707
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Cerebrovascular and Carotid Artery Diseases
  • Prostate Cancer Diagnosis and Treatment
  • Spine and Intervertebral Disc Pathology
  • Cervical and Thoracic Myelopathy
  • Renal cell carcinoma treatment
  • Urological Disorders and Treatments
  • Advanced X-ray and CT Imaging
  • Spinal Fractures and Fixation Techniques
  • Viral Infections and Immunology Research
  • Respiratory viral infections research
  • Prostate Cancer Treatment and Research
  • Spinal Hematomas and Complications
  • Liver Disease and Transplantation
  • Cancer-related molecular mechanisms research
  • Hepatitis B Virus Studies
  • Renal and related cancers
  • Urinary Bladder and Prostate Research
  • Bladder and Urothelial Cancer Treatments
  • Medical Imaging and Analysis
  • Cholinesterase and Neurodegenerative Diseases
  • Oropharyngeal Anatomy and Pathologies
  • CNS Lymphoma Diagnosis and Treatment
  • Case Reports on Hematomas
  • Ureteral procedures and complications

Yuhuangding Hospital
2019-2025

Qingdao University
2022-2025

Capital Medical University
2021-2025

Beijing Tongren Hospital
2022-2025

Yichang Central People's Hospital
2023-2024

China Three Gorges University
2016-2024

Henan Provincial People's Hospital
2015-2024

Jiaxing University
2009-2024

Jilin University
2024

First Hospital of Jiaxing
2019-2024

Aims To predict the probability of a seizure‐free (SF) state in patients with epilepsy (PWEs) after treatment levetiracetam and to identify clinical electroencephalographic (EEG) factors that affect outcomes. Methods Retrospective analysis PWEs treated for 3 years identified 22 who were SF 24 not. Before starting levetiracetam, 11 four EEG features (sample entropy α, β, θ, δ) identified. Overall, 80% each two groups chosen establish support vector machine (SVM) model 5‐fold cross‐validation,...

10.1111/bcp.13720 article EN British Journal of Clinical Pharmacology 2018-07-25

Bilirubin may prevent lipid peroxidation and have important antiatherosclerotic effects. We determined associations of serum bilirubin with peripheral atherosclerosis.We included 4290 participants (35% men; median age, 60 years) from the southeast China who underwent B-mode ultrasound examination. Increased intima-media thickness or a focal structure encroaching into arterial lumen by at least 0.5 mm >50% surrounding value was regarded as having atherosclerosis. Fasting levels were measured....

10.1161/atvbaha.122.318086 article EN Arteriosclerosis Thrombosis and Vascular Biology 2022-12-01

To evaluate the feasibility, effectiveness and therapeutic outcomes of a novel pure retroperitoneoscopic extravesical bladder cuff excision (PREBE) in patients with upper tract urothelial carcinoma (UTUC), retrospectively comparative study between PREBE traditional laparoscopic nephroureterectomy (TLNU) was done single center. We evaluated 72 diagnosed UTUC at our hospital from January 2022 to 2024. The who underwent TLNU (n = 35) 37) were consecutively enrolled. kidney...

10.1007/s11255-025-04414-4 article EN cc-by-nc-nd International Urology and Nephrology 2025-02-27

To investigate the efficacy and safety of local intra-arterial chemotherapy combined with immune checkpoint inhibitors in treatment unresectable head neck squamous cell carcinoma (HNSCC). A retrospective analysis was conducted on clinical data eight patients diagnosed HNSCC at our hospital from January to December 2023. All were by pathological diagnosis treated inhibitors. The overall response rate (ORR), progression-free survival (PFS), (OS), adverse reactions observed. study cohort...

10.1002/hed.28121 article EN Head & Neck 2025-03-06

e17566 Background: Neutropenia is the most common hematological toxicity of myelosuppressive chemotherapy. To observe efficacy and safety efbemalenograstim alfa in prevention absolute neutrophil count (ANC) reduction after chemotherapy Ovarian cancer(OC) Cervical cancer(CC) patients at risk platinum-containing with factors febrile neutropenia (FN). Methods: This study was a single-arm, multicenter clinical trial(NCT06251947). A total 83 would be enrolled, including 55 primary epithelial OC...

10.1200/jco.2025.43.16_suppl.e17566 article EN Journal of Clinical Oncology 2025-05-28

Respiratory syncytial virus (RSV) is the leading cause of childhood respiratory infections worldwide. However, no vaccine available for children, and treatment options are limited. Identification host factors pivotal to viral replication or immune-inflammatory regulation may inform development novel therapies, prophylaxes, diagnoses. The chemokine (C-X-C motif) ligand 11 (CXCL11), which drastically increased in RSV-infected tract samples, was previously found via a metatranscriptome screen,...

10.1093/jimmun/vkaf098 article EN PubMed 2025-05-30

1. Polymorphisms of cytochrome P450 2C19 (CYP2C19) is an important factor contributing to variability voriconazole pharmacokinetics. CYP3A4, CYP3A5, CYP2C9 and non-genetic factors such as age, gender, body mass index (BMI), transaminase levels, concomitant medications might also affect initial steady serum trough concentration (VICmin) in haematological patients, but the effects were not clear. 2. Eighteen single-nucleotide polymorphisms CYP2C19, genotyped. Patients stratified into two...

10.1080/00498254.2016.1271960 article EN Xenobiotica 2016-12-19

Abstract Adenoviruses are highly prevalent pathogens responsible for a wide range of clinical diseases, including respiratory tract infection, acute gastroenteritis, and conjunctivitis. However, adenovirus infection is rarely associated with central nervous system involvement. Here, we report fatal viral sepsis encephalitis in child caused by human type 7 infection. We detected the patient’s nasopharyngeal swab, blood, cerebrospinal fluid. Our findings indicate clinicians should be aware...

10.1186/s12985-022-01886-z article EN cc-by Virology Journal 2022-09-28

BACKGROUND:To explore the diagnostic value of sagittal measurement thoracic inlet parameters for degenerative cervical spondylotic myelopathy (DCSM). MATERIAL AND METHODS:Sixty patients with DCSM (study group) and same number normal subjects (control were initially enrolled in study. All data from X-ray standing position computed tomography (CT) supine collected carefully analyzed. Cervical parameters, including C2–C7 angle, vertical axis (C2–C7 SVA), T1 slope, angle (TIA), neck tilt (NT),...

10.12659/msm.906417 article EN Medical Science Monitor 2018-02-07

Abstract Alzheimer’s disease (AD), the most common type of dementia, is a neurodegenerative disorder with hidden onset, including difficult early detection and diagnosis. Nevertheless, new crucial biomarkers for diagnosis pathogenesis AD need to be explored further. Here, differentially expressed genes (DEGs) were identified through comprehensive analysis gene expression profiles from Gene Expression Omnibus (GEO) database. Furthermore, Ontology Kyoto Encyclopedia Genes Genomes pathway...

10.1515/tnsci-2021-0009 article EN cc-by-nc-nd Translational Neuroscience 2021-01-01

Human metapneumovirus (HMPV) infection is one of the leading causes hospitalization in young children with acute respiratory illness. In this study, we prospectively collected tract samples from who were hospitalized lower six hospitals China 2017 to 2019. HMPV was detected 145 out 2733 (5.3%) children. The majority HMPV-positive under age two (67.6%), a median year. can independently cause children, while all patients showed mild clinical symptoms. Of co-infected patients, most commonly...

10.1016/j.virs.2022.08.007 article EN cc-by-nc-nd Virologica Sinica 2022-08-22

The purpose of this study was to examine whether a single episode traumatic subarachnoid hemorrhage (tSAH) could cause superficial siderosis the central nervous system (SS-CNS).This approved by local ethics committee. Thirty-two patients with history tSAH were enrolled in study. An confirmed based on CT scan or lumbar puncture, and follow-up examination conducted at least six weeks after brain trauma. A MRI performed, using enhanced gradient echo T2 star-weighted angiography (ESWAN) detect...

10.1371/journal.pone.0116632 article EN cc-by PLoS ONE 2015-02-03

Abstract Background Stringent nonpharmaceutical interventions (NPIs) have been implemented worldwide to combat the COVID-19 pandemic, and circulation seasonality of common respiratory viruses subsequently changed. There few multicentre studies or comparisons prevalence accounting for community-acquired pneumonia (CAP) in hospitalized children between pre-COVID period after community school reopening setting zero-COVID policy. Methods We included 1543 with CAP who required hospitalization...

10.1007/s00705-023-05698-6 article EN cc-by Archives of Virology 2023-01-13

Mesenteric ischemia results in blood flow that is insufficient to meet metabolic demands and subsequent dysfunction of visceral organs, including arterial obstruction venous thrombosis. Sustained mesenteric exhausts the ability capillaries provide oxygen initiate an inflammatory reaction, eventually leads intestinal mucosal necrosis, a serious potentially life-threatening condition. Therefore, it essential predictors risk factors for necrosis patients with thrombus are explored.This study...

10.21037/atm-20-8154 article EN Annals of Translational Medicine 2021-02-01

WU polyomavirus (WUPyV) is a novel member of the family Polyomaviridae recently detected in respiratory tract specimens. So far, it has not been proven whether WUPyV real causative agent for diseases. In this study, we described two patients with fatal infection who had their nasopharyngeal swabs. Furthermore, conducted multicentre study six hospitals from different districts China. was by real-time polymerase chain reaction assays, and clinical molecular epidemiological characteristics...

10.3389/fcimb.2021.835946 article EN cc-by Frontiers in Cellular and Infection Microbiology 2022-03-11

Abstract Background MicroRNAs (miRNAs) serve as novel promising biomarkers for the diagnosis and prognosis of many human diseases. This study investigated diagnostic value miR-186-5p asymptomatic carotid artery stenosis (CAS), its predictive future cerebral ischemic events (CIEs). Methods Sixty-seven cases with CAS 60 healthy individuals were recruited. Serum levels tested by using qRT-PCR. Receiving–operator characteristic (ROC) curve was drawn based on sensitivity specificity analyses. All...

10.1186/s13000-020-01007-w article EN cc-by Diagnostic Pathology 2020-07-30

Abstract Background Rhinovirus is a common viral aetiology of upper respiratory infection and mostly associated with cold or flu-like illness. Although rhinovirus has been recognized as pathogen for lower infections in severe cases credited to advances molecular detection, central nervous system involvement multiorgan dysfunction are extremely rare. Case presentation A previously healthy 10-year-old girl developed fever, sore throat conjunctive injection after contact an patient, followed by...

10.1186/s12985-022-01799-x article EN cc-by Virology Journal 2022-04-22

Objective To investigate the clinical characteristics and outcomes of three patients with symptomatic Spinal epidural lipomatosis (SEL) treated using Unilateral Biportal Endoscopic (UBE) surgery. Methods This report retrospectively analyzed data SEL admitted to our hospital. The analysis covers onset characteristics, manifestations, most recent radiologic grading system neural compression (Manjila classification). Furthermore, it details decompression accomplished through application a...

10.3389/fsurg.2024.1309202 article EN cc-by Frontiers in Surgery 2024-03-12

Tuberculous spondylitis following percutaneous vertebroplasty or kyphoplasty is rare. In this, we report a rare case of tuberculous diagnosed after (PVP). A 69-year-old female sought came to our department with history chest and back pain from the last two months accompanied by weakness in both lower limbs. The patient underwent procedures at local hospital within years for compression fractures lumbar thoracic spine. Due continuous PVP surgery, along worsening limbs over past 2 months,...

10.2147/idr.s496726 article EN cc-by-nc Infection and Drug Resistance 2024-11-01
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