Alberto Carturan
A5021779507- CAR-T cell therapy research
- Immune Cell Function and Interaction
- Viral Infectious Diseases and Gene Expression in Insects
- Cancer Immunotherapy and Biomarkers
- Acute Myeloid Leukemia Research
- Immunotherapy and Immune Responses
- Chronic Myeloid Leukemia Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Epigenetics and DNA Methylation
- Blood disorders and treatments
- Synthesis and Biological Evaluation
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Integrated Circuits and Semiconductor Failure Analysis
- Nanofabrication and Lithography Techniques
- Glioma Diagnosis and Treatment
- Silicon Carbide Semiconductor Technologies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Single-cell and spatial transcriptomics
- Hematological disorders and diagnostics
- Acute Lymphoblastic Leukemia research
- CRISPR and Genetic Engineering
- Lymphoma Diagnosis and Treatment
- Pancreatic function and diabetes
- Diet, Metabolism, and Disease
- Renal and related cancers
University of Pennsylvania
2023-2025
Hospital of the University of Pennsylvania
2024-2025
UPMC Hillman Cancer Center
2024
Marche Polytechnic University
2021-2023
Ospedali Riuniti di Ancona
2020
Most patients treated with US Food and Drug Administration (FDA)–approved chimeric antigen receptor (CAR) T cells eventually experience disease progression. Furthermore, CAR have not been curative against solid cancers several hematological malignancies such as cell lymphomas, which very poor prognoses. One of the main barriers to clinical success adoptive immunotherapies is dysfunction lack expansion and/or persistence after infusion. In this study, we found that CD5 inhibits activation...
Abstract Background Commercial anti-CD19 chimeric antigen receptor T-cell therapies (CART19) are efficacious against advanced B-cell non-Hodgkin lymphoma (NHL); however, most patients ultimately relapse. Several mechanisms contribute to this failure, including CD19-negative escape and CAR T dysfunction. All four commercial CART19 products utilize the FMC63 single-chain variable fragment (scFv) specific a CD19 membrane-distal epitope characterized by slow association (on) dissociation (off)...
The presence of neutrophilic leukocytosis may underlie a wide variety diseases. Some rare causes neutrophilia might be chronic leukemia (CNL) and myelodysplastic/myeloproliferative neoplasm with (MDS neutrophilia). Here we report case 78-year-old woman who came to our ER due severe anemia on routine check-up. patient was asymptomatic the last exams available showed mild leukopenia thrombocytopenia. abdominal echography splenomegaly underwent bone marrow (BM) examinations. One week later,...