- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cancer-related molecular mechanisms research
- Heart Failure Treatment and Management
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Bone Tissue Engineering Materials
- Cardiovascular Function and Risk Factors
- Cardiovascular Syncope and Autonomic Disorders
- Additive Manufacturing and 3D Printing Technologies
- Cardiac Fibrosis and Remodeling
- Vitamin C and Antioxidants Research
- Lipoproteins and Cardiovascular Health
- Plant-based Medicinal Research
- Acute Myocardial Infarction Research
- Drug-Induced Hepatotoxicity and Protection
- Calcium Carbonate Crystallization and Inhibition
- Tracheal and airway disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Heart Rate Variability and Autonomic Control
- Heart rate and cardiovascular health
- Frailty in Older Adults
- Aluminum Alloys Composites Properties
- Inflammatory mediators and NSAID effects
Hebei Medical University
2014-2025
Second Hospital of Hebei Medical University
2014-2025
Qingdao University
2011-2024
Affiliated Hospital of Qingdao University
2024
Shanxi Provincial Cancer Hospital
2024
Anglia Ruskin University
2018-2023
Hunan University of Traditional Chinese Medicine
2022
Hull York Medical School
2013-2021
Castle Hill Hospital
2017-2021
University of Hull
2012-2021
Background: Initial observational studies and a systematic review published recently have suggested that non-steroidal anti-inflammatory drug (NSAID) use has the trend to be associated with reduced risk of Alzheimer's disease (AD), while results remain conflicting. Thus, we performed an updated meta-analysis reevaluate evidence on this association. Methods: Data sources from PUBMED, Embase Cochrane Library inception through April 2017 were searched by two independent reviewers. Eligible...
Background: Arterial calcification is a major event in the progression of atherosclerosis. It reported that statins exhibit various protective effects against vascular smooth muscle cell (VSMC) inflammation and proliferation cardiovascular remodeling. Although counteract atherosclerosis, molecular mechanisms on calcium release from VSMCs have not been clearly elucidated. Methods: Calcium content was measured using enzyme-linked immunosorbent assay (ELISA). The expression proteins involved...
Frailty is common in patients with chronic heart failure (CHF) and associated poor outcomes. The natural history of frail CHF unknown.Frailty was assessed using the clinical frailty scale (CFS) 467 consecutive (67% male, median age 76 years, NT-proBNP 1156 ng/L) attending a routine follow-up visit. Those CFS > 4 were classified as frail. We investigated relation between treatments, hospitalisation death CHF.206 (44%) Of 291 HF reduced ejection fraction (HeFREF), those who (N = 117; 40%) less...
The identification of new risk factors for coronary artery disease (CAD) is increasingly sought in an effort to tackle this threatening disease. β2-microglobulin (B2M) reported associate with peripheral arterial and adverse cardiovascular outcomes. However, the association between B2M remains under-researched. This study evaluated effects on CAD without renal dysfunction.One thousand seven hundred sixty-two subjects (403 non-CAD 1,359 subjects) were investigated. Fasting samples collected...
Abstract Background The primary aim was to observe the predictive value of P-wave ECG index and left atrial appendage volume (LLAV) for fibrillation recurrence after first radiofrequency catheter ablation. Methods A total 196 patients with paroxysmal were enrolled. preoperative LLAV measured by cardiac enhanced CT. including minimum duration (P-min), maximum (P-max), mean (mPWD), dispersion (PWD), terminal force in lead V1 (PtfV1), PR interval prolongation, interatrial block (IAB) analyzed...
5514 Background: Cervical cancer is the fourth common malignancy in women, with a 5-year overall survival rate of 24%-76.1%. At present, there are few studies on targeted drugs combined concurrent chemoradiotherapy (CCRT) for locally advanced cervical (LACC) and results were not satisfactory. This CC3 study first randomized, controlled, multicenter phase 3 trial EGFR CCRT cancer, aims to evaluate efficacy safety nimotuzumab (humanized EGFR) combination LACC. (NCT04678791). Methods: All...
Background: The objective of the study was to investigate relationship between baseline blood pressure (BP) and magnitude BP reduction in patients with essential hypertension treated nifedipine gastrointestinal therapeutic system (NGTS). Methods patients: One hundred thirty-eight were enrolled this prospective, single-arm, open-label study. NGTS administered for 24 weeks achieve target 140/90 mmHg. dose could be uptitrated 60 mg/d case unsatisfactory after 4-week treatment. Home measurement...
To compare the safety and efficacy of completely zero-fluoroscopy radiofrequency ablation (RFA) with that conventional RFA guided by three-dimensional mapping in Chinese children paroxysmal supraventricular tachycardia (PSVT). The study had a single-center observational design included 46 aged 6-14 years who underwent for PSVT at Second Hospital Hebei Medical University between March 2019 September 2021. were divided according to whether they (zero-fluoroscopy group, n = 26) or routine under...
Objective: To evaluate the diagnostic effectiveness of discography in discogenic low back pain (LBP). Methods: Ninety‐six cases chronic LBP with or without referred thigh were enrolled this study. All these received CT scan following once conservative treatment for at least 6 months had failed. There 42 men and 54 women, aged from 24 to 67 years (average 46.4). Discography was performed on 218 discs. The positive discs classified morphologically according Dallas Discogram Description (DDD)....
Introduction: Differentiating idiopathic premature ventricular contractions (PVCs) originating from the right and left outflow tracts with a bundle branch block (LBBB) morphology is relevant to catheter ablation planning important for lowering risk of complications. This study established novel electrocardiographic (ECG) criterion discriminate PVCs septum tract (s-RVOT) those aortic sinus cusp (LVOT-ASC). Methods: A total 259 patients LBBB pattern who underwent successful were...
Early intervention of long-acting nifedipine GITS reduces brachial–ankle pulse wave velocity and improves arterial stiffness in Chinese patients with mild hypertension: a 24-week, single-arm, open-label, prospective study Jidong Zhang, Yan Wang, Haijuan Hu, Xiaohong Yang, Zejun Tian, Demin Liu, Guoqiang Gu, Hongmei Zheng, Ruiqin Xie, Wei Cui Department Cardiology, The Second Hospital Hebei Medical University, Shijiazhuang, Hebei, People’s Republic China Background: Nifedipine...
Objective The aim of this study was to evaluate the association between subclinical thyroid dysfunction and recurrence atrial fibrillation (AF) after radiofrequency catheter ablation (RFCA). Methods We examined AF at a large university-affiliated cardiac arrhythmia center in China. Data were collected from consecutive patients who underwent RFCA for AF, excluding those with history hypothyroidism, hyperthyroidism, or ongoing medical treatment hypothyroidism biochemically defined overt...