A5100446333- Advanced Fluorescence Microscopy Techniques
- Ginseng Biological Effects and Applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- Plasmonic and Surface Plasmon Research
- Near-Field Optical Microscopy
- Optical Coatings and Gratings
- Digital Holography and Microscopy
- Spectroscopy and Quantum Chemical Studies
- Natural product bioactivities and synthesis
- Antenna Design and Analysis
- Microwave Engineering and Waveguides
- Pharmacological Effects of Natural Compounds
- Quantum optics and atomic interactions
- Liver Disease Diagnosis and Treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Advanced Fiber Laser Technologies
- Spectroscopy and Laser Applications
- Optical Coherence Tomography Applications
- Advanced Optical Sensing Technologies
- Optical Polarization and Ellipsometry
- Photoacoustic and Ultrasonic Imaging
- Microbial Metabolic Engineering and Bioproduction
- Laser-induced spectroscopy and plasma
- Image Processing Techniques and Applications
- Antenna Design and Optimization
State Key Laboratory of Remote Sensing Science
2018-2024
Chinese Institute for Brain Research
2021-2024
Ningxia Medical University
2024
Shanghai Academy of Spaceflight Technology
2024
Shenyang University of Chemical Technology
2024
Tongji Hospital
2016-2023
Huazhong University of Science and Technology
2011-2023
Chalmers University of Technology
2023
Changsha Medical University
2023
Nanchang Hangkong University
2008-2022
Abstract Background Two important flavonoids, kaempferol and quercetin possess remarkably potent biological impacts on human health. However, their structural complexity low abundance in nature make both bulk chemical synthesis extraction from native plants difficult. Therefore microbial production via heterologous expression of plant enzymes can be a safe sustainable route for production. Despite several attempts reported hosts, the levels still stay far behind compared to many other...
We proposed a novel architecture for optical image encryption based on interference between two polarized wavefronts. A polarization-selective diffractive element is employed to generate the desired wavefronts by modulating incident light beam. The algorithm this new method simple and does not need iterative encoding. Numerical simulation performed demonstrate validity of method.
Docetaxel (DTX) resistance reduces therapeutic efficacy in prostate cancer (PCa). Accumulating reports support the role of phytochemicals reversal DTX resistance. This study aimed to determine whether Epimedium brevicornu and Curcuma zedoaria extracts (ECe), specially icariin-curcumol, attenuates explore their potential mechanisms.Regulatory pathways were predicted between ECe active ingredients PCa using network pharmacology. DTX-resistant cell LNCaP/R established based on DTX-sensitive...
Abstract Cdc37, as a kinase-specific co-chaperone of the chaperone Hsp90AA1 (Hsp90), actively aids with maturation, stabilization and activation cellular or viral kinase/kinase-like targets. Phosphoprotein (P) rabies virus (RABV) is multifunctional, non-kinase protein involved in interferon antagonism, transcription replication. Here, we demonstrated that RABV P chaperoned by Cdc37 Hsp90 during infection. We found affect life cycle directly. Activity inhibition knockdown increased...
Abscisic acid (ABA) plays an important role in abiotic stress response and physiological signal transduction resisting to the adverse environment. Therefore, it is very essential for quantitative detection of abscisic due its indispensable plant activities. Herein, a new method based on localized surface plasmon resonance (LSPR) using aptamer-functionalized gold nanoparticles (AuNPs) developed without expensive instrument antibody. In presence ABA, ABA specifically bind with their aptamers...
Ginsenoside Rb1 has been reported to exert anti-aging and anti-neurodegenerative effects. In the present study, we investigate whether ginsenoside is involved in neurite outgrowth neuroprotection against damage induced by amyloid beta (25–35) cultured hippocampal neurons, explore underlying mechanisms. significantly increased expression of phosphorylated-Akt phosphorylated extracellular signal-regulated kinase 1/2. These effects were abrogated API-2 PD98059, inhibitors signaling proteins Akt...
Stachydrine is a main active component of Leonurus japonicus (Chinese motherwort), which has traditionally been used to promote postpartum recovery and alleviate myocardial cerebral ischemic injuries due its pro-angiogenic effect. Our prior study demonstrated that stachydrine increased angiogenesis in zebrafish embryos, but effect underlying mechanisms on human umbilical vein endothelial cells (HUVECs) remain largely unknown. In the present study, we further investigated role...
BACKGROUND Alzheimer’s disease (AD) is a progressive neurodegenerative disorder currently lacking effective therapeutic interventions. Pathological hallmarks of AD include intracellular neurofibrillary tangles (NFTs) and extracellular amyloid beta (Aβ) plaques. Neuroplastin 65 (NP65), highly expressed in the brain, has been previously shown to mitigate cognitive impairments decrease Aβ plaques mouse model, suggesting that NP65 involved neuropathology. However, direct evidence linking...
A new method for accurate measurement of the threshold value stimulated Brillouin scattering (SBS) in water terms pump laser intensity is investigated. The SBS determined by point deviation attenuation coefficients wide- and narrow-linewidth lasers rather than backscattered signal material.
Increasing epidemiological evidence has indicated that inherited variations of mtDNA content could affect the genetic susceptibility many malignancies in a tumor‐specific manner. However, association between and hepatocellular carcinoma (HCC) remains undetermined. In this study, peripheral blood leukocytes was determined using quantitative real‐time PCR case–control study consisting 274 HCC cases, 126 non‐cancer patient controls with chronic liver diseases (CLD), 258 healthy controls. We...
Ginsenoside Rg1 (Rg1) has anti-aging and anti-neurodegenerative effects. However, the mechanisms underlying these actions remain unclear. The aim of present study was to determine whether affects hippocampal survival neurite outgrowth in vitro after exposure amyloid-beta peptide fragment 25–35 (Aβ25–35), explore extracellular signal-regulated kinase (ERK) Akt signaling pathways are involved biological processes. We cultured neurons from newborn rats for 24 hours, then added medium another...
It is investigated experimentally that stimulated Raman scattering (SRS) can be enhanced by Brillouin (SBS). Two physical mechanisms of these phenomena were analyzed. These show not only the competition between SBS and SRS exists, pumping effect on back-stimulated also a commonly existing rule regardless experimental conditions.
The utilization of interfacial polymerization in the preparation microcapsules with a slow-controlled release has been shown to effectively improve pesticide efficacy and reduce environmental pollution. In this study, polyurea loaded lambda-cyhalothrin were prepared by an method using modified isocyanate (MDI) as wall material GT-34 initiator. fully characterized optical microscopy, scanning electron Fourier transform infrared spectroscopy, thermogravimetric analysis, etc., behaviors...
Abstract With the rapid development of wearable devices, tactile sensors have received extensive attention as supplements to vision and hearing. However, it remains challenging for a single sensor generate distinguishable electrical signals when receiving mechanical stimuli in different directions. Herein, novel flexible electromagnetic (FETS) prepared by combining double‐layer coils tilted magnetic column array (TMCA) is presented. Flexible high‐density are fabricated using...
Abstract Motivation: One of the most promising applications biosynthetic methods is to produce chemical products high value from ready-made chemicals. To explore potentials a as synthesis precursor, databases and related chemoinformatics tools are urgently needed. In present work, web-based tool, BioSynther, developed precursor chemicals using BKM-react, Rhea, more than 50 000 in-house RxnFinder reactions manually curated. BioSynther allows researchers potentials, through so far known...