A5046378271- Antifungal resistance and susceptibility
- Pneumocystis jirovecii pneumonia detection and treatment
- Fungal Infections and Studies
- Tuberculosis Research and Epidemiology
- Infective Endocarditis Diagnosis and Management
- Long-Term Effects of COVID-19
- Pneumonia and Respiratory Infections
- Cytomegalovirus and herpesvirus research
- Antimicrobial Resistance in Staphylococcus
- Mycobacterium research and diagnosis
- Bacterial Identification and Susceptibility Testing
- Antibiotics Pharmacokinetics and Efficacy
- Streptococcal Infections and Treatments
- Antibiotic Resistance in Bacteria
- Neutropenia and Cancer Infections
- Respiratory viral infections research
- COVID-19 and healthcare impacts
- Herpesvirus Infections and Treatments
- Infectious Diseases and Mycology
- Urinary Tract Infections Management
- COVID-19 Clinical Research Studies
- Central Venous Catheters and Hemodialysis
- Pain Mechanisms and Treatments
- Disaster Response and Management
- Hepatitis B Virus Studies
Hospital de Nens de Barcelona
2017-2024
Agència de Qualitat i Avaluació Sanitàries de Catalunya
2016-2023
Hospital General de Catalunya
2019-2020
Instituto de Salud Carlos III
2017
Red Espanola de Investigacion en Patologia Infecciosa
2017
Joint Commission
2017
Vall d'Hebron Hospital Universitari
2012-2015
Universitat Autònoma de Barcelona
2015
Instituto Ramón y Cajal de Investigación Sanitaria
2014
Hospital Universitario Ramón y Cajal
2012
Tuberculosis is a particularly important condition in solid-organ transplant recipients because of the delay treatment caused by difficulties involved its diagnosis and pharmacological toxicity associated with this treatment. Both are responsible for many clinical complications high mortality tuberculosis population. The Consensus Statement from Spanish Group Study Infectious Diseases Transplant Recipients defines indications latent infection recipients, especially patients risk toxicity, as...
A study was designed to assess the reliability of serial detection Aspergillus sp. DNA diagnose invasive aspergillosis (IA) in patients with febrile neutropenia. Two blood and two serum samples were taken weekly from 83 patients. total 2,244 analyzed by real-time quantitative PCR. Twelve (14.4%) diagnosed IA. Taking consecutive positive results as diagnostic criterion, PCR detected 11 cases, 4 false positives, giving sensitivity, specificity, positive, negative predictive values 91.6%,...
BackgroundNew techniques, such as those based on multiplex quantitative real-time PCR (MRT-PCR), can improve the detection of invasive candidiasis (IC).
ABSTRACT β-Lactam/β-lactamase inhibitors (BLBLIs) were compared to carbapenems in two cohorts of hematological neutropenic patients with extended-spectrum-β-lactamase (ESBL) bloodstream infection (BSI): the empirical therapy cohort (174 patients) and definitive (251 patients). The 30-day case fatality rates other secondary outcomes similar groups also propensity-matched cohorts. BLBLIs might be carbapenem-sparing alternatives for treatment BSI due ESBLs these patients.
Treatment failure occurs in about 25% of patients with methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia. We assessed whether cloxacillin plus fosfomycin achieves better treatment success than alone hospitalized adults MSSA conducted a multicenter, open-label, phase III-IV superiority randomized clinical trial. randomly assigned (1:1) to receive 2 g intravenous every 4 h or 3 6 for the initial 7 days. The primary endpoint was at day 7, composite following criteria: patient...
A. Garcia‐Reyne, F. López‐Medrano, J.M. Morales, C. García Esteban, I. Martín, Eraña, Y. Meije, Lalueza, Alastruey‐Izquierdo, J.L. Rodríguez‐Tudela, Aguado. Cutaneous infection by Phomopsis longicolla in a renal transplant recipient from Guinea: first report of human this fungus. Transpl Infect Dis 2011: 13: 204–207. All rights reserved Abstract: We the case 72‐year‐old female with nodular lesion distal phalange third left finger produced dematiaceous fungus that was identified as . She...
Relevance of viral and bacterial coinfection (VBC) in non-intensive care unit (ICU) hospitalized adults with community-acquired pneumonia (CAP) is poorly characterized. We aim to determine risk factors, features, outcomes VBC-CAP this setting.This a prospective cohort admitted conventional wards CAP. Patients were divided into VBC-CAP, CAP (V-CAP), (B-CAP) groups. Independent prognostic factors for identified.We documented 1123 episodes: 57 (5.1%) 98 (8.7%) V-CAP, 968 (86.1%) B-CAP. younger...
AimsTo characterize the distribution and severity of sensory neuropathy using a portable quantitative testing (QST) device in diabetic patients (DM) hospitalized with severe COVID-19 infection.MethodsFour diabetes SARS-CoV-2 requiring non-invasive ventilation for protracted duration underwent clinical, laboratory radiologic assessment detailed evaluation neuropathic symptoms, neurological assessment, QST on dorsum foot face NerveCheck Master taste smell.ResultsAll four subjects developed...
We assessed whether multiplex real-time PCR plus conventional microbiological testing is safe and more effective than alone for reducing antibiotic use in community-acquired pneumonia (CAP). In this randomised trial, we recruited adults hospitalised with CAP at four Spanish hospitals. Patients were randomly assigned (1:1) to undergo either non-invasive respiratory samples or alone. The primary endpoint was measured by days of therapy (DOT). Between February 20, 2020, April 24, 2023, 242...
Abstract Background This study aimed to characterize the dynamics of acquisition cytomegalovirus ( CMV )‐specific cell‐mediated immunity CMI ) in donor positive/recipient negative solid organ transplant SOT patients receiving long‐term antiviral prophylaxis, and determine whether development confers protection against disease. Methods A prospective multicenter was conducted Spain from September 2009 2012. Whole blood specimens were prospectively collected at 30, 90, 120, 200, 365 days after...
Abstract Background Cytomegalovirus ( CMV )‐negative recipients of a graft from ‐positive donor (D+/R−) are at high risk disease. Current preventive strategies include universal prophylaxis UP ) and preemptive therapy PT ). However, the best strategy to prevent disease achieve better long‐term outcomes remains matter debate. Methods We analyzed incidence including dysfunction patient mortality 5 years after transplantation with both strategies. High‐risk kidney liver transplant RESITRA...
Whether echinocandins could be used to treat candidemia of a urinary tract source (CUTS) is unknown. We aimed provide current epidemiological information CUTS and compare echinocandin fluconazole treatment on outcomes.A multicenter study adult patients with was conducted in 9 hospitals. defined as concomitant candiduria by the same organism associated significant urological comorbidity. The primary outcome assessed clinical failure (defined 7-day mortality or persistent candidemia) treated...