A5032455453- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- Electrospun Nanofibers in Biomedical Applications
- Mesenchymal stem cell research
- Oral microbiology and periodontitis research
- Polymer Surface Interaction Studies
- Dental Implant Techniques and Outcomes
- Tendon Structure and Treatment
- Orthodontics and Dentofacial Orthopedics
- Tissue Engineering and Regenerative Medicine
- Periodontal Regeneration and Treatments
- Electrocatalysts for Energy Conversion
- Silk-based biomaterials and applications
- Advanced battery technologies research
- Temporomandibular Joint Disorders
- Immunotherapy and Immune Responses
- Wound Healing and Treatments
- Dental Trauma and Treatments
- Fuel Cells and Related Materials
- TGF-β signaling in diseases
- Cardiovascular Health and Risk Factors
- Infant Nutrition and Health
- Wnt/β-catenin signaling in development and cancer
- Neonatal and Maternal Infections
- Parkinson's Disease Mechanisms and Treatments
The First Affiliated Hospital, Sun Yat-sen University
2007-2025
Chongqing Medical University
2016-2025
Second Affiliated Hospital of Chongqing Medical University
2023-2025
Ningbo University
2023-2025
Dalian Medical University
2023-2025
Zhongshan Hospital
2024-2025
Fudan University
2024-2025
Sun Yat-sen University
2007-2025
Ningbo University Affiliated Hospital
2025
Taiyuan University of Technology
2019-2024
Abstract Exploring and developing high‐efficiency electrocatalysts for the oxygen evolution reaction (OER) is desirable yet challenging cost‐effective transformation of renewable electricity into fuels chemicals. Herein, a self‐supported electrode nanoflower‐like Ce‐modified Ni(OH) 2 grown on high‐conductivity NiSe octahedra nanoparticles designed fabricated first time. By virtue i) high conductivity support favorable electron transfer; ii) open porous structure from beneficial mass...
Nanohydroxyapatite (HA) synthesized by biomimetic strategy is a promising nanomaterial as bone substitute due to its physicochemical features similar those of natural nanocrystal in tissue. Inspired mussel adhesive chemistry, novel nano-HA was our work employing polydopamine (pDA) template under weak alkaline condition. Subsequently, the as-prepared pDA-templated HA (tHA) introduced into polycaprolactone (PCL) matrix via coelectrospinning, and bioactive tHA/PCL composite nanofiber scaffold...
Abstract In recent years, growing concerns regarding energy efficiency and heat mitigation, along with the critical goal of carbon neutrality, have drawn human attention to zero‐energy‐consumption cooling technique. Passive daytime radiative (PDRC) can be an invaluable tool for combating climate change by dispersing ambient directly into outer space instead just transferring it across surface. Although significant progress has been made in mechanisms, materials design, application...
Abstract Nanodrug delivery systems (NDDSs) for the treatment of periodontitis remain a significant clinical challenge. The low biocompatibility, singular effect, and lack disease specificity conventional nanoparticles limit their biomedical application. Recent studies have highlighted pivotal role cell membrane‐coated nanotechnology in anti‐inflammatory strategies due to its improved biocompatibility superior biointerface properties. Herein, combined with pathological heterogeneity revealed...
Poly(lactic-glycolic acid) (PLGA) is a biocompatible bio-scaffold material, but its own hydrophobic and electrically neutral surface limits application as cell scaffold. Polymer materials, mimics ECM organic material have often been used coating materials for PLGA scaffolds to improve the poor adhesion of enhance tissue adaptation. These can be modified on via simple physical or chemical methods, multiple simultaneously confer different functions scaffold; not only does this ensure stronger...
The design and development of functional biomimetic systems for programmed stem cell response is a field topical interest. To mimic bone extracellular matrix, we present an innovative strategy constructing drug-loaded composite nanofibrous scaffolds in this study, which could integrate multiple cues from calcium phosphate mineral, bioactive molecule, highly ordered fiber topography the control fate. Briefly, inspired by mussel adhesion mechanism, polydopamine (pDA)-templated...
Abstract In recent years, the field of metal-halide perovskite emitters has rapidly emerged as a new community in solid-state lighting. Their exceptional optoelectronic properties have contributed to rapid rise external quantum efficiencies (EQEs) light-emitting diodes (PeLEDs) from <1% (in 2014) over 30% 2023) across wide range wavelengths. However, several challenges still hinder their commercialization, including relatively low EQEs blue/white devices, limited large-area poor device...
Abstract Achilles tendinopathy (AT) is an injury caused by overuse of the tendon or sudden force on tendon, with a considerable inflammatory infiltrate. As progresses, inflammation and factors affect remodeling extracellular matrix (ECM) tendon. Gastrodin(Gas), main active ingredient Astrodia has anti‐inflammatory, antioxidant, anti‐apoptotic properties. The small intestinal submucosa (SIS) naturally decellularized matrix(dECM)material high content growth as well good biocompatibility....
Abstract: The construction of functional biomimetic scaffolds that recapitulate the topographical and biochemical features bone tissue extracellular matrix is now topical interest in engineering. In this study, a novel surface-functionalized electrospun polycaprolactone (PCL) nanofiber scaffold with highly ordered structure was developed to simulate critical native via single step catechol chemistry. Specially, under slightly alkaline aqueous solution, polydopamine (pDA) coated on surface...
Reducing early nonbacterial inflammation induced by implanted materials and infection resulting from bacterial contamination around the implant-abutment interface could greatly decrease implant failure rates, which would be of clinical significance. In this work, we presented a facile versatile strategy for construction anti-inflammatory antibacterial surfaces. Briefly, surfaces polystyrene culture plates were first coated with polydopamine then decorated dexamethasone plus...
Endoplasmic reticulum (ER) dysfunction is a potential contributor to the impaired repair capacity of periodontal tissue in diabetes mellitus (DM) patients. Restoring ER homeostasis thus critical for successful regenerative therapy diabetic tissue. Recent studies have shown that metformin can modulate DM-induced dysfunction, yet its mechanism remains unclear. Herein, we show high glucose elevates intracellular miR-129-3p level due exocytosis-mediated release failure and subsequently perturbs...
Association of prodromal Parkinson's disease (PD) with risk PD and mortality in individuals warrant investigation through large-scale prospective study. We included 501,475 participants without at baseline. Eight features were measured. Incident cases identified via hospital admission, death register, self-report. Cox regression models used to compute hazard ratios (HRs) 95% confidence intervals (CIs). Multivariable-adjusted HRs3+vs.0 95%CIs 3.12 (2.58–3.78) for men 2.71 (2.11–3.47) women....
Abstract Bone regeneration is synergistically regulated by growth factors, which are expressed in a coordinated cascade of events. An ideal guided bone membrane (GBRM) shall present barrier and antibacterial functions, promote osteogenesis through time‐controlled release factors. In this study, therapy‐based Janus fibrous fabricated coaxial electrospinning layer‐by‐layer self‐assembly technology (LBL). Specifically, the oriented PCL/PLGA fibers loaded with zinc oxide nanoparticles (ZnO NPs)...
Bone morphogenetic protein 9 (BMP9) exhibits remarkable osteogenic potential. However, the intricate mechanisms driving this function of BMP9 remain elusive. This study endeavors to investigate potential role sirtuin 5 (SIRT5) in enhancing BMP9's capacity and decipher underlying molecular pathways. To achieve aim, we employed real-time PCR, western blotting, histochemical staining, a cranial defect repair model assess impact SIRT5 on BMP9-mediated osteogenesis. We utilized immunofluorescent...
This study mainly explores the possible role and mechanism of pyruvate dehydrogenase kinase 4 (PDK4) in onset development Glucocorticoid-induced osteoporosis (GIOP), seeks potential targets for treatment GIOP. Mesenchymal stem cells (MSCs) were treated with osteogenic induction medium. An vitro damage model was established by exposing MSCs to a high concentration (10− 6 M) dexamethasone (DEX). Osteogenic markers measured real-time quantitative polymerase chain reaction, western blot,...