A5015088031- Adipose Tissue and Metabolism
- Cancer-related molecular mechanisms research
- Genetic and phenotypic traits in livestock
- Liver Disease Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Gut microbiota and health
- Peroxisome Proliferator-Activated Receptors
- Plant Gene Expression Analysis
- Plant Stress Responses and Tolerance
- Endoplasmic Reticulum Stress and Disease
- Plant Molecular Biology Research
- MicroRNA in disease regulation
- Genetic Mapping and Diversity in Plants and Animals
- Cholesterol and Lipid Metabolism
- Ginger and Zingiberaceae research
- RNA modifications and cancer
- Exercise and Physiological Responses
- Animal Nutrition and Physiology
- Circular RNAs in diseases
- Grouting, Rheology, and Soil Mechanics
- Muscle Physiology and Disorders
- Livestock Farming and Management
- Lipid metabolism and biosynthesis
- Effects of Environmental Stressors on Livestock
- Folate and B Vitamins Research
Northeast Forestry University
2023-2025
Sichuan Agricultural University
2024
Guangxi University
2019-2024
Hebei University of Technology
2024
Beijing Chao-Yang Hospital
2024
Capital Medical University
2024
State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2020-2023
Northwest A&F University
2012-2023
Shantou University
2023
Shantou University Medical College
2023
MicroRNAs constitute a class of ~22-nucleotide non-coding RNAs. They modulate gene expression by associating with the 3' untranslated regions (3' UTRs) messenger RNAs (mRNAs). Although multiple miRNAs are known to be regulated during myoblast differentiation, their individual roles in muscle development still not fully understood. In this study, we showed that miR-199a-3p was highly expressed skeletal and induced C2C12 myoblasts differentiation. We also identified confirmed several genes...
MicroRNAs (miRNAs), a class of small non-coding RNAs, have emerged as novel and potent regulators adipogenesis. However, few miRNAs been fully investigated in porcine adipogenesis, given the fact that pig is not only an apropos model human obesity research, but also staple meat source diet. In this study, we showed miRNA-199a-5p highly expressed subcutaneous fat deposits compared to several other tissue types organs measured alongside. Overexpression miR-199a-5p preadipocytes significantly...
Zinc deficiency is a risk factor for the development of obesity and diabetes. Studies have shown lower serum zinc levels in obese individuals those with We speculate that supplementation can alleviate diabetes and, to some extent, their complications. To test our hypothesis, we investigated effects on mice high-fat diet (HFD)-induced hepatic steatosis vivo vitro by adding medium HepG2 cells. Both results showed high could glucose lipid metabolic disorders induced HFD. High reduce production,...
Luchuan pig is a typical obese breed in China, and the diameter area of its longissimus dorsi muscle fibers are significantly smaller than those Duroc (lean) pig. Skeletal fiber characteristics related to meat quality livestock. There significant correlation between different breeds pork fiber, which an important factor affecting pork. The growth development. Therefore, we used assay for transposase-accessible chromatin using sequencing (ATAC-seq) RNA (RNA-seq) analysis investigate potential...
Fat tail is a unique trait in sheep acquired during domestication. Several genomic analyses have been conducted breeds from limited geographic origins to identify the genetic factors underlying this trait. Nevertheless, these studies obtained different candidates. The results of regional were easily biased by breed structures.To minimize bias and distinguish true candidates, we used an extended data set 968 representing 18 fat-tailed 14 thin-tailed around world, integrated two statistical...
Iris laevigata Fisch. is an excellent ornamental plant in cold regions due to its unique ability and strong resistance. However, the flowering period of population only about 20 days, greatly limiting potential uses landscaping cutting flower industry. In addition, I. often challenged with various abiotic stresses including high salinity drought native habitats. Thus, breeding novel cultivars delayed time higher resistance stress importance. this study, we utilized sequencing data from...
Non-alcoholic fatty liver disease (NAFLD) affects over 25% of the general population and lacks an effective treatment. Recent evidence implicates disrupted mitochondrial calcium homeostasis in pathogenesis hepatic steatosis.In this study, uniporter (MCU) was inhibited through classical genetic approaches, viral vectors or small molecule inhibitors vivo to study its role steatosis induced by high-fat diet (HFD). In vitro, MCU overexpressed change homeostasis, endoplasmic...
Abstract Background In the livestock industry, intramuscular fat content is a key factor affecting meat quality. Many studies have shown that dietary calcium supplementation closely related to lipid metabolism. However, few examined relationship between and accumulation. Methods Here, we used C2C12 cells, C57BL/6 mice ( n = 8) three-way cross-breeding pigs (Duroc×Landrace×Large white) 10) study effect of addition on vitro, chloride adjust levels in medium (2 mmol/L or 3 mmol/L). Then...
Drought and high salinity greatly affect plant growth development. WRKY transcription factors play a key role in tolerance to abiotic stress, but the functions of WRKYs ornamental monocotyledon Iris laevigata remain largely unexplored. In this study, we cloned IlWRKY70 found that it is Group III localized nucleus. The expression was induced by NaCl PEG-6000, which reached peaks (4.38 5.65 times) after 3 h 1 h, respectively. exogenous overexpression N. tabacum significantly improved...
Emerging evidence indicates that air pollutants contribute to the development and progression of gastrointestinal diseases. However, there is scarce an association with appendicitis in mainland China.In this study, Linfen city, one most polluted cities China, was selected as study site explore whether could affect admissions identify susceptible populations. Daily data on three principal pollutants, including inhalable particulate matter (PM10), nitrogen dioxide (NO2), sulfur (SO2) were...
Abstract Aging, chronic high-fat diet feeding, or housing at thermoneutrality induces brown adipose tissue (BAT) involution, a process characterized by reduction of BAT mass and function with increased lipid droplet size. Single nuclei RNA sequencing aged mice identifies specific adipocyte population Ucp1 -low cells that are pyroptotic display in the longevity gene syntaxin 4 ( Stx4a ). Similar to adipocytes, Ucp1-STX4KO loss thermogenic dysfunction concomitant pyroptosis. Restoration STX4...
Type 2 diabetes (T2D) is a chronic metabolic disorder characterized by hyperglycemia and dyslipidemia. The termite fungus comb an integral component of nests termites, which are global pest. Termite polysaccharides (TFCPs) have been identified to possess antioxidant, anti-aging, immune-enhancing properties. However, their physicochemical characteristics role in fighting not previously reported. In the current study, TFCPs were isolated structurally characterized. yield was determined be...
The adverse effect of ambient PM2.5 exposure on very early pregnancy (VEP) remains controversial among epidemiological studies but is supported by toxicological evidence. We adopted a multicenter retrospective cohort 141,040 cycles to evaluate the VEP using in vitro fertilization and embryo transfer platform high-resolution data China. first investigated association between 1 week before after date VEP. average concentrations 2 weeks were approximately 47 μg/m3. pooled results revealed...
To tackle the high resource consumption in occluded person re-identification, sparse attention mechanisms based on Vision Transformers (ViTs) have become popular. However, they often suffer from performance degradation with long sequences, omission of crucial information, and token representation convergence. address these issues, we introduce AIRHF-Net: an Adaptive Interaction Representation Hierarchical Fusion Network, named AIRHF-Net, designed to enhance pedestrian identity recognition...
An excessive high-fat/energy diet is a major cause of obesity and linked complications, such as non-alcoholic fatty liver disease (NAFLD). Betaine has been shown to effectively improve hepatic lipid metabolism. However, the mechanistic basis for this improvement largely unknown. Herein, integration mRNA sequencing ribosome footprints profiling (Ribo-seq) was used investigate means by which betaine alleviates metabolic disorders induced high-fat diet. For transcriptome, gene set enrichment...
Taking the sandstone subjected to pH = 1 and 3 HCl solutions as research object, a dynamic chemical damage model was established based on mineral dissolution theory kinetics principles. A mechanical of also by continuous mechanics theory. Moreover, coupled deduced through microstress analysis, constitutive for acid-corroded constructed Weibull distribution D–P criterion. The results showed that acid–rock reaction evident time dependence, rate decreased with prolongation corrosion time....
Cyclin C (CCNC) is the most conserved subunit of Mediator complex, which an important transcription cofactor. Recently, we have found that CCNC facilitates brown adipogenesis in vitro by activating C/EBPα-dependent transcription. However, role adipose tissue (BAT) vivo remains unclear.We generated conditional knock-out mice crossing Ccncflox/flox with Myf5Cre, Ucp1Cre or AdipoqCre transgenic to investigate BAT development and function. We applied glucose insulin tolerance test, cold exposure...
The broiler industry frequently encounters 2 common problems: excessive deposition of abdominal fat and poor quality meat. However, there are limited nutritional manipulation strategies to address these issues. While Anoectochilus roxburghii (Wall.) Lindl., a traditional Chinese herb, has been shown have multiple beneficial effects in humans, its potential roles chickens remain unexplored. In this study, the dietary supplementation with extract (ARE) on growth performance, deposition, meat...