A5066500926- Bone Tissue Engineering Materials
- Dental materials and restorations
- Electrospun Nanofibers in Biomedical Applications
- Orthopaedic implants and arthroplasty
- Graphene and Nanomaterials Applications
- Dental Implant Techniques and Outcomes
- Advanced Nanomaterials in Catalysis
- Nanoparticle-Based Drug Delivery
- Bone Metabolism and Diseases
- Bone health and treatments
- Polymer Surface Interaction Studies
- Metal and Thin Film Mechanics
- Surface Treatment and Residual Stress
- biodegradable polymer synthesis and properties
- Laser Applications in Dentistry and Medicine
- Curcumin's Biomedical Applications
- Laser-Ablation Synthesis of Nanoparticles
- Silk-based biomaterials and applications
- Cancer, Lipids, and Metabolism
- Intestinal and Peritoneal Adhesions
- Titanium Alloys Microstructure and Properties
- Calcium Carbonate Crystallization and Inhibition
- Nanocluster Synthesis and Applications
- Advancements in Transdermal Drug Delivery
- Lubricants and Their Additives
Wenzhou Medical University
2014-2025
Wenzhou University
2021
Sichuan University
2014
State Key Laboratory of Oral Diseases
2014
Stomatology Hospital
2012
The excessive accumulation of reactive oxygen species (ROS) under osteoporosis precipitates a microenvironment with high levels oxidative stress (OS). This could significantly interfere the bioactivity conventional titanium implants, impeding their early osseointegration bone. We have prepared series strontium (Sr)-doped implants via micro-arc oxidation (MAO) to verify efficacy and differences in osteoinduction capabilities normal osteoporotic (high OS levels) conditions. Apart from chemical...
The aim of the study was to investigate a porous nanohydroxyapatite/polyamide 66 (n-HA/PA66) scaffold material that implanted into muscle and tibiae 16 New Zealand white rabbits evaluate biocompatibility osteogenesis osteoinductivity materials in vivo. samples were harvested at 2, 4, 12 26 weeks respectively, subjected histological analysis. At 2 weeks, experiment showed detected n-HA/PA66 composite density new bone formation similar surrounding host weeks. indicated three-dimensional pore...
Abstract Background Oral squamous cell carcinoma (OSCC) is one of the most prevalent and fatal oral cancers. Mitochondria-targeting therapies represent promising strategies against various cancers, but their applications in treating OSCC are limited. Alantolactone (ALT) possesses anticancer properties also regulates mitochondrial events. In this study, we explored effects ALT on related mechanisms. Methods The cells were treated with varying concentrations duration N -Acetyl- l -cysteine...
Antibacterial and osteogenic functionalization of titanium (Ti) implants will greatly expand their clinical indications in immediate implant therapy, accelerate osteointegration, enhance long-term prognosis. We had recently shown that the high-energy shot peening (HESP)-assisted micro-arc oxidation (MAO) significantly improved bioactivity coating stability Ti-based substrates. In this study, we further functionalized Ti with antibacterial properties by doping silicon (Si) and/or copper (Cu)...
Zirconia (ZrO2) has emerged as a preferred material for dental implants due to its excellent chemical inertness, absence of metal allergies and esthetic appeal. However, limited bioactivity regarding infection resistance early osseointegration hinders implantation success rate compared titanium implants. Herein, we developed PDPA@Sr/BP coating ZrO2 address these limitations. First, inspired by the adhesive properties mussel foot proteins, PDPA@Sr enriched with positively charged amine groups...
Surface characteristics of and in vitro behavior osteoblast-like cells on titanium with nanotopography prepared by high-energy shot peening Zhennan Deng,1,2 Baodi Yin,1 Weihong Li,1 Jinsong Liu,1 Jingyuan Yang,1 Tieli Zheng,1 Dafeng Zhang,1 Haiyang Yu,2 Xiaoguang Liu,3 Jianfeng Ma1 1School Hospital Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic China; 2State Key Laboratory Oral Diseases, West China 3National Engineering Research Center for Biomaterials, Sichuan...
The accelerating bone healing process is still a major challenge in clinical orthopedics, especially critical-sized defects. Recently, Nanofiber membranes are showing increasing attention the biomedical field due to their good biocompatibility, mechanical stability, and ability work as drug carrier achieve localized sustained delivery. Herein, multifunction nanofiber membrane loaded with vitamin D (Vit D) curcumin (Cur) was successfully fabricated using electrospinning technology. In...
Phosphorus incorporation further boosted the OER activity of cation-doped Co-based spinel oxides <italic>via</italic> remarkably tuning oxygen vacancies, crystallinity and electrochemically active surface area on surface.
Background: Although titanium dioxide nanotubes (TNTs) had great potential to promote osteogenesis, their weak bonding strength with substrates greatly limited clinical application. Purpose: The objective of this study was maintain porosity and improve the stability TNT coatings by preparing some micro-patterned mesoporous/nanotube (MP/TNT) structures via a photolithography-assisted anodization technology. Methods: adhesion different studied ultrasonic cleaning machine scratch tester. early...
BACKGROUND:Ideal bone repair material should be of good biocompatibility and high bioactivity. Besides, their mechanical properties equivalent to those natural bone. The objective this study was fabricate a novel biocomposite suitable for load-bearing defect repair. MATERIAL AND METHODS:A composed carbon fiber, hydroxyapatite polyamide46 (CF/HA/PA46) fabricated, its performances preliminary cell responses were evaluated explore feasibility RESULTS:The resultant CF/HA/PA46 showed bending...